Homology Based Structure Predictions Hemochromatosis

Hemochromatosis>>Task 4: Homology based structure predictions

Riddle of the task

After endless battles and deadly traps you have finally reached the tomb's final chamber. As you enter it you notice that there is no sign of the treasures that were promised by the old map you found months ago. Suddenly you hear a loud noise behind you and a solid wall of stone blocks the only entrance into the room. You are trapped! You look around and notice something on the walls. On the left wall are four runes in an ancient language. Luckily its the same language as the notes on the map you deciphered and they translate into four single letters:

• C N O I

On the opposite wall you can see four simple symbols:

• a triangle
• a square
• a circle
• and a diamond (dt. Raute)

After further investigation you notice that the four symbols can be pushed into the wall, but you don't know what would happen and which one(s) to push.

What do you do?

Short Task Description

Detailed description: Homology based structure predictions

Protocol

A protocol with a description of the data acquisition and other scripts used for this task is available here.

PDB templates

<figtable id="coma_t">

TODO: COMA: Top10 (e-Value) sorted by Identities.

PDB ID	e-Value	Identities	Positives
1a6z_A	1.00E-63	100%	100%
1t7v_A	1.20E-63	34%	62%
3nwm_A	1.60E-57	30%	57%
1frt_A	4.90E-65	28%	66%
2wy3_A	2.80E-63	26%	66%
3ov6_A	2.70E-55	20%	67%
1u58_A	1.00E-54	19%	59%
3d2u_A	7.50E-60	16%	70%
3dbx_A	9.70E-59	16%	71%
3it8_D	3.40E-52	15%	65%

</figtable>

<figtable id="hhpred_t">

TODO: HHpred: Top10 (e-Value) sorted by Identities.

PDB ID	e-Value	Identities	Similarity
1a6z_A	1.80E-69	100%	1.623
1k5n_A	2.80E-68	40%	0.725
1s7q_A	5.80E-78	37%	0.655
1t7v_A	7.40E-68	36%	0.702
3p73_A	1.10E-69	35%	0.638
3bev_A	1.00E-69	34%	0.684
2yf1_A	2.40E-74	32%	0.617
1zs8_A	7.30E-68	30%	0.553
2wy3_A	3.30E-68	29%	0.496
1cd1_A	1.60E-67	21%	0.394

</figtable>