Difference between revisions of "Task diseaseInfo"
From Bioinformatikpedia
m |
m |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
| − | * For the disease that we have assigned to you, look up the diesease in |
+ | * For the disease that we have assigned to you, look up the diesease in Wikipedia, OMIM, HGMD and any other resource you find. |
* Document the resources you have found in this Wiki (resources section). |
* Document the resources you have found in this Wiki (resources section). |
||
* Produce a 5 min presentation for our first practical session. |
* Produce a 5 min presentation for our first practical session. |
||
| − | * Document the information about the disease in |
+ | * Document the information about the disease in [[Protein Structure and Function Analysis (SS 2013)|this Wiki]]: Fill the link in section Diseases. |
| + | ** see [[Example/Template]] for a suggestions how to structure the information |
||
| + | ** see [[Metachromatic leukodystrophy]] for an example protein (unfinished) |
||
* Here is a minimal list of aspects to look for: |
* Here is a minimal list of aspects to look for: |
||
** Phenotypic description of the disease. |
** Phenotypic description of the disease. |
||
** Biochemical disease mechanism. |
** Biochemical disease mechanism. |
||
| + | ** Info about the gene and inheritance. |
||
** Current knowledge about mutations associated with the disease. |
** Current knowledge about mutations associated with the disease. |
||
| + | * '''Try to find connections''' between your data, e.g. |
||
| + | ** How are the symptoms related? |
||
| + | ** Why does a defect in that gene cause the observed phenotype? |
||
| + | ** How does the treatment improve the phenotype? |
||
| + | ** Could you imagine any other treatment? Why might it not work? |
||
Latest revision as of 13:25, 21 February 2013
- For the disease that we have assigned to you, look up the diesease in Wikipedia, OMIM, HGMD and any other resource you find.
- Document the resources you have found in this Wiki (resources section).
- Produce a 5 min presentation for our first practical session.
- Document the information about the disease in this Wiki: Fill the link in section Diseases.
- see Example/Template for a suggestions how to structure the information
- see Metachromatic leukodystrophy for an example protein (unfinished)
- Here is a minimal list of aspects to look for:
- Phenotypic description of the disease.
- Biochemical disease mechanism.
- Info about the gene and inheritance.
- Current knowledge about mutations associated with the disease.
- Try to find connections between your data, e.g.
- How are the symptoms related?
- Why does a defect in that gene cause the observed phenotype?
- How does the treatment improve the phenotype?
- Could you imagine any other treatment? Why might it not work?
