Difference between revisions of "Fabry:Sequence alignments (sequence searches and multiple alignments):Results"

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=== Comparison ===
 
=== Comparison ===
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==== Comparing the hits ====
 
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| [[File:venn_blast_hhblits.png|thumb| Venn diagram of proteins found by BLAST, HHBlits and HHBlits with 8 iterations]]
 
| [[File:venn_blast_hhblits.png|thumb| Venn diagram of proteins found by BLAST, HHBlits and HHBlits with 8 iterations]]
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Venn diagrams created with [http://bioinfogp.cnb.csic.es/tools/venny/index.html Oliveros, J.C. (2007) VENNY. An interactive tool for comparing lists with Venn Diagrams.]
 
Venn diagrams created with [http://bioinfogp.cnb.csic.es/tools/venny/index.html Oliveros, J.C. (2007) VENNY. An interactive tool for comparing lists with Venn Diagrams.]
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==== Comparing the Evalues ====
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[[File:Fabry_animation.gif]]

Revision as of 07:06, 5 May 2012

Please see Task 2 for our scripts and line of action on this topic.

Sequence searches

Blast

GO terms of P06280 and each BLAST hit (with Evalue <= 0.003) compared. Percentage terms shared, in relation to number of GO terms of P06280 (AGAL_HUMAN) in the upper picture, in the secon picture in relation to number of each hit
Histogram of the logarithmic E-values of the BLAST hits for P06280
Histogram of the positive amino acids of the pairwise alignments of the BLAST hits for P06280
Histogram of the identical amino acids of the pairwise alignments of the BLAST hits for P06280
Histogram of the length of the BLAST hits for P06280

Number of hits with Evalue < 0.003: 663

Psi-Blast

HHblits

2 iterations - default

GO terms of P06280 and each HHblits hit (with Evalue < 0.003) compared. Percentage terms shared, in relation to number of GO terms of P06280 (AGAL_HUMAN) in the upper picture, in the secon picture in relation to number of each hit
Histogram of the logarithmic E-values of the HHblits hits for P06280

Number of hits with Evalue < 0.003: 326

Histogram of the similarity of the HHblits hits to P06280
Histogram of the identical amino acids of the pairwise alignments of the HHblits hits for P06280

8 iterations

GO terms of P06280 and each HHblits hit (with Evalue < 0.003 and 8 iterations) compared. Percentage terms shared, in relation to number of GO terms of P06280 (AGAL_HUMAN) in the upper picture, in the secon picture in relation to number of each hit
Histogram of the logarithmic E-values of the HHblits search with 8 iterations for P06280

Number of hits with Evalue < 0.003: 729

Histogram of the similarity of the BLAST hits (search with 8 iterations) to P06280
Histogram of the identical amino acids of the pairwise alignments of the BLAST hits (search with 8 iterations) for P06280

Comparison

Comparing the hits

Venn diagram of proteins found by BLAST, HHBlits and HHBlits with 8 iterations
Venn diagram of the proteins found by BLAST, Psi-BLAST (10 iterations and E-value cutoff 10e-10 ) and HHBlits with 8 iterations
Venn diagram of the first 100 proteins found by BLAST, HHBlits and HHBlits with 8 iterations
Venn diagram of the first 100 proteins found by BLAST, Psi-BLAST and HHBlits with 8 iterations

Venn diagrams created with Oliveros, J.C. (2007) VENNY. An interactive tool for comparing lists with Venn Diagrams.

Comparing the Evalues

Fabry animation.gif