TSD PolyPhen2 Full Ouput
From Bioinformatikpedia
#o_acc o_pos o_aa1 o_aa2 rsid acc pos aa1 aa2 nt1 nt2 prediction based_on effect pph2_class pph2_prob pph2_FPR pph2_TPR pph2_FDR site region PHAT dScore Score1 Score2 MSAv Nobs Nstruct Nfilt PDB_id PDB_pos PDB_ch ident length NormASA SecStr MapReg dVol dProp B-fact H-bonds AveNHet MinDHet AveNInt MinDInt AveNSit MinDSit Transv CodPos CpG MinDJxn PfamHit IdPmax IdPSNP IdQmin P06865 1 M V ? P06865 1 M V A G benign alignment_mz ? neutral 0.063 0.16 0.937 0.187 NO SIGNAL ? +1.023 -1.918 -2.941 3 22 20 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0 0 2 +253 NO 4.746 ? 68.62 P06865 39 L R ? P06865 39 L R T G probably damaging alignment ? deleterious 1 0.00026 0.00018 0.0109 NO PROPEP ? +2.829 -1.397 -4.226 2 143 20 8 2gk1 39 G 0.97 506 0.007 . B 6 1.75 0.28 ? ? ? 2 4.308 ? ? 1 1 2 +138 PF02838.10 2.588 ? 81.29 P06865 58 C Y ? P06865 58 C Y G A probably damaging sequence annotation 1.2 deleterious 1 0.00026 0.00018 0.0109 DISULFID PROPEP ? +3.177 -1.130 -4.307 2 157 20 8 2gk1 58 G 0.97 506 0.019 . b 85 0.25 -0.87 ? ? ? 1 5.995 ? ? 0 1 0 +81 PF02838.10 1.449 ? 80.53 P06865 127 L R ? P06865 127 L R T G probably damaging alignment ? deleterious 1 0.00026 0.00018 0.0109 NO NO ? +3.154 -0.995 -4.149 2 184 20 8 2gk1 127 G 0.97 506 ? E b 6 1.75 0.07 ? ? ? ? ? ? ? 1 1 2 +33 PF02838.10 0.971 ? 47.26 P06865 170 R W ? P06865 170 R W C T probably damaging alignment ? deleterious 1 0.00026 0.00018 0.0109 NO NO ? +4.550 -0.852 -5.402 2 184 20 8 2gk1 170 G 0.97 506 ? E b 54 1.67 -1.08 ? ? ? ? ? ? ? 0 0 1 -49 PF00728.17 0.234 ? 46.69 P06865 178 R H ? P06865 178 R H G A probably damaging structure 2.2.3 deleterious 1 0.00026 0.00018 0.0109 NO NO ? +3.460 -0.910 -4.370 2 184 20 8 2gk1 178 G 0.97 506 0.098 T A -20 1.03 -0.37 ? 1 2.763 2 3.248 1 5.536 0 1 1 +38 PF00728.17 1.430 ? 46.69 P06865 210 S F ? P06865 210 S F C T probably damaging alignment ? deleterious 1 0.00026 0.00018 0.0109 NO NO ? +3.402 -0.744 -4.146 2 188 20 8 2gk1 210 G 0.97 506 ? B B 101 0.85 0.14 ? ? ? ? ? ? ? 0 1 0 +44 PF00728.17 ? ? ? P06865 258 D H ? P06865 258 D H G C probably damaging alignment ? deleterious 1 0.00026 0.00018 0.0109 NO NO ? +3.876 -0.658 -4.534 2 187 20 8 2gk1 258 G 0.97 506 ? E B 42 0.58 -0.18 ? 1 5.060 ? ? ? ? 1 0 0 +34 PF00728.17 ? ? ? P06865 451 L V ? P06865 451 L V C G probably damaging alignment ? deleterious 0.994 0.0289 0.689 0.0537 NO NO ? +2.175 -1.080 -3.255 2 186 20 8 2gk1 451 G 0.97 506 0.387 T A -27 0.11 -0.25 ? ? ? ? ? ? ? 1 0 0 -21 PF00728.17 2.746 ? 56.71 P06865 482 E K ? P06865 482 E K G A probably damaging alignment ? deleterious 1 0.00026 0.00018 0.0109 NO NO ? +2.379 -0.707 -3.086 2 185 20 8 2gk1 482 G 0.97 506 ? H A 30 1.3 -1.23 ? ? ? ? ? ? ? 0 0 1 -23 PF00728.17 ? ? ? ## Sources: ## Predictions: PolyPhen-2 v2.2.2r398 ## Sequences: UniProtKB/UniRef100 Release 2011_12 (14-Dec-2011) ## Structures: PDB/DSSP Snapshot 03-Jan-2012 (78304 Structures) ## Genes: UCSC MultiZ46Way GRCh37/hg19 (08-Oct-2009)
