Task 9 (MSUD)

From Bioinformatikpedia
Revision as of 11:06, 12 July 2013 by Weish (talk | contribs) (Visualization of mutant structures)

Results

Lab journal

For this task we have chosen 5 mutations from HGMD and dbSNP. 2 of them are neutral mutations which do not have functional changes over the protein structure. Following are the 5 mutations: TODO: TABLE

Visualization of mutant structures

The mutagen tool of PyMOL was used to introduce mutations to the protein structure. Mutations and their neighboring residues are visualized and shown in following figures.

Mutant structures (SCWRL)

Energy comparisons

FoldX

Minimise

Gromacs