Difference between revisions of "Task 7: Structure-based mutation analysis"

From Bioinformatikpedia
(Selection of protein structure)
Line 5: Line 5:
 
== Selection of protein structure ==
 
== Selection of protein structure ==
   
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We had the following choice of reference structures for [http://www.uniprot.org/uniprot/P00439#section_x-ref PAH]:
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  +
{| border="1"
  +
|-
  +
! Entry
  +
! Method
  +
! Resolution (A)
  +
! Chain
  +
! Positions
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|-
  +
| 1DMW
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| X-Ray
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| 2.00
  +
| A
  +
| 118-424
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|-
  +
| 1J8T
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| X-Ray
  +
| 1.70
  +
| A
  +
| 103-427
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|-
  +
| 1J8U
  +
| X-Ray
  +
| 1.50
  +
| A
  +
| 103-427
  +
|-
  +
| 1KW0
  +
| X-Ray
  +
| 2.50
  +
| A
  +
| 103-427
  +
|-
  +
| 1LRM
  +
| X-Ray
  +
| 2.10
  +
| A
  +
| 103-427
  +
|-
  +
| 1MMK
  +
| X-Ray
  +
| 2.00
  +
| A
  +
| 103-427
  +
|-
  +
| 1MMT
  +
| X-Ray
  +
| 2.00
  +
| A
  +
| 103-427
  +
|-
  +
| 1PAH
  +
| X-Ray
  +
| 2.00
  +
| A
  +
| 117-424
  +
|-
  +
| 1TDW
  +
| X-Ray
  +
| 2.10
  +
| A
  +
| 117-424
  +
|-
  +
| 1TG2
  +
| X-Ray
  +
| 2.20
  +
| A
  +
| 117-424
  +
|-
  +
| 2PAH
  +
| X-Ray
  +
| 3.10
  +
| A/B
  +
| 118-452
  +
|-
  +
| 3PAH
  +
| X-Ray
  +
| 2.00
  +
| A
  +
| 117-424
  +
|-
  +
| 4PAH
  +
| X-Ray
  +
| 2.00
  +
| A
  +
| 117-424
  +
|-
  +
| 5PAH
  +
| X-Ray
  +
| 2.10
  +
| A
  +
| 117-424
  +
|-
  +
| 6PAH
  +
| X-Ray
  +
| 2.15
  +
| A
  +
| 117-424
  +
|}
   
 
== Mapping mutations to the structure ==
 
== Mapping mutations to the structure ==

Revision as of 17:11, 30 June 2011

Task description

A detailed task description can be found here.

Selection of protein structure

We had the following choice of reference structures for PAH:

Entry Method Resolution (A) Chain Positions
1DMW X-Ray 2.00 A 118-424
1J8T X-Ray 1.70 A 103-427
1J8U X-Ray 1.50 A 103-427
1KW0 X-Ray 2.50 A 103-427
1LRM X-Ray 2.10 A 103-427
1MMK X-Ray 2.00 A 103-427
1MMT X-Ray 2.00 A 103-427
1PAH X-Ray 2.00 A 117-424
1TDW X-Ray 2.10 A 117-424
1TG2 X-Ray 2.20 A 117-424
2PAH X-Ray 3.10 A/B 118-452
3PAH X-Ray 2.00 A 117-424
4PAH X-Ray 2.00 A 117-424
5PAH X-Ray 2.10 A 117-424
6PAH X-Ray 2.15 A 117-424

Mapping mutations to the structure