Difference between revisions of "Task 6: Sequence-based mutation analysis"

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(Mutation selection)
(Mutation selection)
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The encrypted output is as follows:
 
The encrypted output is as follows:
  +
[[File:Encrypted img.png]
 
 
VimCrypt~01!.
 
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F*tiv ~;o�/��r�7���~n��^��ιF
 
���.��s�Ɂ��9�%� r��_�K��މ�<�S����&1(�
 
��:[�b���=c �UY���@��#;��
 
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Revision as of 17:07, 23 June 2011

Task description

A detailed task description can be found here.

Task description

A detailed task description can be found here.

Mutation selection

We selected the following ten mutations:

  • I65T
  • R71H
  • R158Q
  • R261Q
  • T266A
  • P275S
  • T278N
  • P281L
  • G312D
  • R408W

5 of these mutations are associated with our disease phenylketonuria the other 5 not. However, at this point we are not going to tell which of these are the associated and which are not. We are going to lift this "secret" after our sequence based mutation analysis in order to validate our in silico generated predictions.

To keep our association secret we encrypted the file which contains the disease association for each mutation with the following linux command: "vim -x selected_mutations_and_association.txt"

The encrypted output is as follows: [[File:Encrypted img.png]


The decryption can be only performed with the correct password.