Difference between revisions of "Talk:Gaucher Disease: Task 02 - Alignments"

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TODO:
 
TODO:
* Maybe an error in Psi-BLAST runs, because all results are the same --> no, only in the first iteration against big the number of hits is the same, but not in the second and not after pdb search (also the profiles are different)- add in the table.
+
* Maybe an error in Psi-BLAST runs, because all results are the same --> no, only in the first iteration against big the number of hits is the same, but not in the second (--> added in the table) and not after pdb search (also the profiles are different).
 
* Move all methods used into "lab journal" page for the task
 
* Move all methods used into "lab journal" page for the task
 
* Explain about checkpoint files in Psi-BLAST
 
* Explain about checkpoint files in Psi-BLAST

Revision as of 21:34, 9 May 2013

TODO:

  • Maybe an error in Psi-BLAST runs, because all results are the same --> no, only in the first iteration against big the number of hits is the same, but not in the second (--> added in the table) and not after pdb search (also the profiles are different).
  • Move all methods used into "lab journal" page for the task
  • Explain about checkpoint files in Psi-BLAST
  • Look at same hits in HHblits and Psi-BLAST: what E-values do they have?
  • Analyse the hits that overlap for both and those which are only found in one of the programs (distributions, evaluation)
  • Write down with which versions (dates) of the databases we worked

- Uniprot_20 (/mnt/project/rost_db/data/hhblits/uniprot_20): 02 Sep 2011 -> now Feb13 is available online! - Big & Big_80 (/mnt/project/rost_db/data/big/big[_80]): before 30 Apr 2013? -> Big is updatet with delay, especially on the student cluster! - pdb_seqres (/mnt/home/rost/kloppmann/data/blast_db/pdb_seqres): 3 May 2013 - pdb_full (mnt/project/rost_db/data/hhblits/pdb_full): before 30 Apr 2013? - COPS (/mnt/project/pracstrucfunc13/data/COPS/COPS-ChainHierarchy.txt): 27 Apr 2012

  • Software sharing: copy paste the code
    • share the evaluation script