TSD PolyPhen2 Full Ouput

From Bioinformatikpedia
#o_acc               	 o_pos	o_aa1	o_aa2	rsid      	acc       	   pos	aa1	aa2	nt1	nt2	        prediction	            based_on	    effect	        pph2_class	 pph2_prob	  pph2_FPR	  pph2_TPR	  pph2_FDR	    site	  region	    PHAT	dScore	Score1	Score2	MSAv	  Nobs	 Nstruct	 Nfilt	PDB_id	PDB_pos	PDB_ch	 ident	length	NormASA	SecStr	MapReg	  dVol	 dProp	B-fact	 H-bonds	 AveNHet	 MinDHet	 AveNInt	 MinDInt	 AveNSit	 MinDSit	Transv	CodPos	CpG	 MinDJxn	     PfamHit	  IdPmax	  IdPSNP	  IdQmin
P06865              	     1	    M	    V	         ?	P06865    	     1	  M	  V	  A	  G	            benign	        alignment_mz	         ?	           neutral	     0.063	      0.16	     0.937	     0.187	      NO	  SIGNAL	       ?	+1.023	-1.918	-2.941	   3	    22	      20	     ?	     ?	      ?	     ?	     ?	     ?	      ?	     ?	     ?	     ?	     ?	     ?	       ?	       ?	       ?	       ?	       ?	       ?	       ?	     0	     0	  2	    +253	          NO	   4.746	       ?	   68.62
P06865              	    39	    L	    R	         ?	P06865    	    39	  L	  R	  T	  G	 probably damaging	           alignment	         ?	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	  PROPEP	       ?	+2.829	-1.397	-4.226	   2	   143	      20	     8	  2gk1	     39	     G	  0.97	   506	  0.007	     .	     B	     6	  1.75	  0.28	       ?	       ?	       ?	       2	   4.308	       ?	       ?	     1	     1	  2	    +138	  PF02838.10	   2.588	       ?	   81.29
P06865              	    58	    C	    Y	         ?	P06865    	    58	  C	  Y	  G	  A	 probably damaging	 sequence annotation	       1.2	       deleterious	         1	   0.00026	   0.00018	    0.0109	DISULFID	  PROPEP	       ?	+3.177	-1.130	-4.307	   2	   157	      20	     8	  2gk1	     58	     G	  0.97	   506	  0.019	     .	     b	    85	  0.25	 -0.87	       ?	       ?	       ?	       1	   5.995	       ?	       ?	     0	     1	  0	     +81	  PF02838.10	   1.449	       ?	   80.53
P06865              	   127	    L	    R	         ?	P06865    	   127	  L	  R	  T	  G	 probably damaging	           alignment	         ?	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	      NO	       ?	+3.154	-0.995	-4.149	   2	   184	      20	     8	  2gk1	    127	     G	  0.97	   506	      ?	     E	     b	     6	  1.75	  0.07	       ?	       ?	       ?	       ?	       ?	       ?	       ?	     1	     1	  2	     +33	  PF02838.10	   0.971	       ?	   47.26
P06865              	   170	    R	    W	         ?	P06865    	   170	  R	  W	  C	  T	 probably damaging	           alignment	         ?	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	      NO	       ?	+4.550	-0.852	-5.402	   2	   184	      20	     8	  2gk1	    170	     G	  0.97	   506	      ?	     E	     b	    54	  1.67	 -1.08	       ?	       ?	       ?	       ?	       ?	       ?	       ?	     0	     0	  1	     -49	  PF00728.17	   0.234	       ?	   46.69
P06865              	   178	    R	    H	         ?	P06865    	   178	  R	  H	  G	  A	 probably damaging	           structure	     2.2.3	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	      NO	       ?	+3.460	-0.910	-4.370	   2	   184	      20	     8	  2gk1	    178	     G	  0.97	   506	  0.098	     T	     A	   -20	  1.03	 -0.37	       ?	       1	   2.763	       2	   3.248	       1	   5.536	     0	     1	  1	     +38	  PF00728.17	   1.430	       ?	   46.69
P06865              	   210	    S	    F	         ?	P06865    	   210	  S	  F	  C	  T	 probably damaging	           alignment	         ?	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	      NO	       ?	+3.402	-0.744	-4.146	   2	   188	      20	     8	  2gk1	    210	     G	  0.97	   506	      ?	     B	     B	   101	  0.85	  0.14	       ?	       ?	       ?	       ?	       ?	       ?	       ?	     0	     1	  0	     +44	  PF00728.17	       ?	       ?	       ?
P06865              	   258	    D	    H	         ?	P06865    	   258	  D	  H	  G	  C	 probably damaging	           alignment	         ?	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	      NO	       ?	+3.876	-0.658	-4.534	   2	   187	      20	     8	  2gk1	    258	     G	  0.97	   506	      ?	     E	     B	    42	  0.58	 -0.18	       ?	       1	   5.060	       ?	       ?	       ?	       ?	     1	     0	  0	     +34	  PF00728.17	       ?	       ?	       ?
P06865              	   451	    L	    V	         ?	P06865    	   451	  L	  V	  C	  G	 probably damaging	           alignment	         ?	       deleterious	     0.994	    0.0289	     0.689	    0.0537	      NO	      NO	       ?	+2.175	-1.080	-3.255	   2	   186	      20	     8	  2gk1	    451	     G	  0.97	   506	  0.387	     T	     A	   -27	  0.11	 -0.25	       ?	       ?	       ?	       ?	       ?	       ?	       ?	     1	     0	  0	     -21	  PF00728.17	   2.746	       ?	   56.71
P06865              	   482	    E	    K	         ?	P06865    	   482	  E	  K	  G	  A	 probably damaging	           alignment	         ?	       deleterious	         1	   0.00026	   0.00018	    0.0109	      NO	      NO	       ?	+2.379	-0.707	-3.086	   2	   185	      20	     8	  2gk1	    482	     G	  0.97	   506	      ?	     H	     A	    30	   1.3	 -1.23	       ?	       ?	       ?	       ?	       ?	       ?	       ?	     0	     0	  1	     -23	  PF00728.17	       ?	       ?	       ?
## Sources:
##   Predictions: PolyPhen-2 v2.2.2r398
##   Sequences:   UniProtKB/UniRef100 Release 2011_12 (14-Dec-2011)
##   Structures:  PDB/DSSP Snapshot 03-Jan-2012 (78304 Structures)
##   Genes:       UCSC MultiZ46Way GRCh37/hg19 (08-Oct-2009)