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(newest | oldest) View (newer 20 | older 20) (20 | 50 | 100 | 250 | 500)- 22:11, 29 June 2011 Braunt (talk | contribs) uploaded File:Active site of 2NT0.png
- 22:09, 29 June 2011 Braunt (talk | contribs) uploaded File:Mutations mapped to 2NT0.png
- 22:03, 29 June 2011 Braunt (talk | contribs) uploaded File:Cartoon scwrl mutations glucocerebrosidase.png (Cartoon representation of 2NT0, chain A (gray) superimposed with the resulting structures of SCWRL (green).)
- 21:55, 29 June 2011 Braunt (talk | contribs) uploaded File:Mutation mapping glucocerebrosidase.jpg (10 Mutations mapped onto 2NT0. red: wildtype, green: scwrl, orange: mutagenesis (pymol).)
- 16:29, 26 June 2011 Braunt (talk | contribs) uploaded File:SIFT multiple alignment GBA.png
- 15:36, 26 June 2011 Braunt (talk | contribs) uploaded File:Protein blast results for GBA.pdf
- 00:32, 26 June 2011 Braunt (talk | contribs) uploaded File:Secondary structure prediction of mutated GBA sequence.pdf
- 17:15, 25 June 2011 Braunt (talk | contribs) uploaded a new version of File:Comparison mutation wildtype glucocerebrosidase.jpg (Mutation 8 changed to H350R)
- 17:14, 25 June 2011 Braunt (talk | contribs) uploaded a new version of File:Selected subset of mutations glucocerebrosidase.png (Mutation 8 changed to H350R)
- 22:47, 21 June 2011 Braunt (talk | contribs) uploaded File:Comparison mutation wildtype glucocerebrosidase.jpg (Wildtype is shown in red, and the mutation in blue. Structure is 1OGS.)
- 22:46, 21 June 2011 Braunt (talk | contribs) uploaded a new version of File:Selected subset of mutations glucocerebrosidase.png (Most common mutation included.)
- 18:40, 21 June 2011 Braunt (talk | contribs) uploaded a new version of File:Selected subset of mutations glucocerebrosidase.png
- 18:38, 21 June 2011 Braunt (talk | contribs) uploaded File:Selected subset of mutations glucocerebrosidase.png (The subset of mutations, selected for the analysis in task 6 is highlighted in the structure of 1OGS. blue : mutation only listed in dbSNP red : mutation only listed in HGMD green: mutation listed in both, dbSNP and HGMD )
- 17:25, 19 June 2011 Braunt (talk | contribs) uploaded a new version of File:Glucocerebrosidase ramachandran plots 3d jigsaw best models.pdf
- 17:20, 19 June 2011 Braunt (talk | contribs) uploaded File:Glucocerebrosidase best models 3d jigsaw.jpg (Models obtained with 3D-Jigsaw based on the following models: model based on 2WNW obtained with MODELLER, model based on 2WNW obtained with SWISS-MODEL (Alignment Mode), model obtained with I-TASSER Run 2/ Model 1)
- 17:18, 19 June 2011 Braunt (talk | contribs) uploaded File:Glucocerebrosidase ramachandran plots 3d jigsaw best models.pdf
- 09:02, 16 June 2011 Braunt (talk | contribs) uploaded File:Additional swiss model output.pdf
- 08:06, 16 June 2011 Braunt (talk | contribs) uploaded File:Glucocerebrosidase superposition 1ogs 2nt0.png (Superposition of 1OGS and 2NT0. 1OGS is shown in red, and 2NT0 in blue. )
- 00:34, 14 June 2011 Braunt (talk | contribs) uploaded File:Comparison area around active site glucocerebrosidase.jpg (Area around active site (30 residues) in different models compared to the reference structure 1OGS.)
- 04:02, 13 June 2011 Braunt (talk | contribs) uploaded File:I tasser results glucocerebrosidase.jpg (Results of the modelling process with I-TASSER. Run 1 = without template restriction Run 2 = exclude templates with sequence identity >80%)