Difference between revisions of "Gaucher Disease: Task 10 - Normal mode analysis"

From Bioinformatikpedia
Line 5: Line 5:
 
'''WEBnm@'''
 
'''WEBnm@'''
 
* Deformation energy
 
* Deformation energy
  +
* atomic fluctuations
*
 
   
   
Line 16: Line 16:
 
==WEBnm@==
 
==WEBnm@==
 
WEBnm@ uses only alpha-carbon atoms in the models for th normal mode analysis.
 
WEBnm@ uses only alpha-carbon atoms in the models for th normal mode analysis.
  +
  +
<figtable id="energy">
  +
{| border="1" cellpadding="2" cellspacing="0" align="center"
  +
! style="background:#adceff;" | Mode
  +
! style="background:#adceff;" | Deformation Energy
  +
|-
  +
|7 1633.42
  +
|-
  +
|8 2358.92
  +
|-
  +
|9 2686.12
  +
|-
  +
|10 4886.37
  +
|-
  +
|11 5221.34
  +
|-
  +
|}
  +
<center><small>'''<caption>''' Range and score distribution of all predicted HRas contacts and HRas contacts between residues with a sequence distance of >5 residues.</caption></small></center>
  +
</figtable>
   
   

Revision as of 22:44, 3 September 2013

lab journal

With normal mode analysis (NMA), you are able to simulate or analyse the natural resonant movements of proteins. There are two different webserver available to do a NMA, WEBnm@ and ElNemo. They provide the following information.

WEBnm@

  • Deformation energy
  • atomic fluctuations


ElNemo


WEBnm@

WEBnm@ uses only alpha-carbon atoms in the models for th normal mode analysis.

<figtable id="energy">

Mode Deformation Energy
7 1633.42
8 2358.92
9 2686.12
10 4886.37
11 5221.34
Range and score distribution of all predicted HRas contacts and HRas contacts between residues with a sequence distance of >5 residues.

</figtable>


ElNemo