Difference between revisions of "Gaucher Disease: Task 05 - Homology Modelling"
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Kalemanovm (talk | contribs) (→Structures from task 04) |
Kalemanovm (talk | contribs) (→Structures from task 04) |
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! style="background:#efefef;" | Structure |
! style="background:#efefef;" | Structure |
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− | ! style="background:#efefef;" | PID |
+ | ! style="background:#efefef;" | PID with target |
− | ! style="background:#efefef;" | |
+ | ! style="background:#efefef;" | Length |
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− | !2xwd_A || 91.51% | |
+ | !2xwd_A || 91.51% || 505 aa |
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|align="center"| 2nsx_A || align="center"| 92.53% || align="center"| 497 aa |
|align="center"| 2nsx_A || align="center"| 92.53% || align="center"| 497 aa |
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|align="center"| 2f7k_A || align="center"| 8.95% || align="center"| 327 aa |
|align="center"| 2f7k_A || align="center"| 8.95% || align="center"| 327 aa |
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− | !2gep_A || | |
+ | !2gep_A || 10.74% || 497 aa |
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|align="center"| 2isb_A || align="center"| 5.59% || align="center"| 192 aa |
|align="center"| 2isb_A || align="center"| 5.59% || align="center"| 192 aa |
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|align="center"| 2djf_C || align="center"| 4.47% || align="center"| 69 aa |
|align="center"| 2djf_C || align="center"| 4.47% || align="center"| 69 aa |
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− | |align="center"| 2qgu || align="center"| |
+ | |align="center"| 2qgu || align="center"| 5.59% || align="center"| 211 aa |
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Revision as of 22:07, 10 June 2013
Contents
Calculation of models
Structures from task 04
We assembled the following structures in Gaucher_Disease:_Task_04_-_Structural_Alignment, now we divide them into two groups at
- > 60% sequence identity to our template protein, P04062 (536 aa)
- < 30% sequence identity (ide ally go towards 20%)
We calculated PID as follows:
- first aligned the two fasta sequences from PDB with ClustalW
- then calculated the PID using SIAS with default options
Selected structures for modelling are written in bold.
Homologous structures to 1ogs_A | ||
---|---|---|
Structure | PID with target | Length |
2xwd_A | 91.51% | 505 aa |
2nsx_A | 92.53% | 497 aa |
2nt1_A | 92.53% | 497 aa |
2f7k_A | 8.95% | 327 aa |
2gep_A | 10.74% | 497 aa |
2isb_A | 5.59% | 192 aa |
2djf_A | 3.17% | 119 aa |
2djf_B | 2.98% | 164 aa |
2djf_C | 4.47% | 69 aa |
2qgu | 5.59% | 211 aa |