Difference between revisions of "Gaucher Disease: Task 05 - Homology Modelling"
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Kalemanovm (talk | contribs) (→Structures from task 04) |
Kalemanovm (talk | contribs) (→Structures from task 04) |
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We assembled the following structures in [[Gaucher_Disease:_Task_04_-_Structural_Alignment]], now we divide them into two groups at |
We assembled the following structures in [[Gaucher_Disease:_Task_04_-_Structural_Alignment]], now we divide them into two groups at |
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* > 60% sequence identity |
* > 60% sequence identity |
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+ | ==Evaluation of models== |
Revision as of 00:04, 10 June 2013
Calculation of models
Structures from task 04
We assembled the following structures in Gaucher_Disease:_Task_04_-_Structural_Alignment, now we divide them into two groups at
- > 60% sequence identity
- < 30% sequence identity (ideally go towards 20%)
For not glucocerebrosidases, we calculated PID as follows:
- first aligned the two fasta sequences from PDB with ClustalW
- then calculated the PID using SIAS with default options
Homologous structures to 1ogs_A | |
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> 60% PID | < 30% PID |
2xwd_A (82.77%) | 2f7k_A (9.65%) |
2nsx_A | 2gep_A (9.66%) |
2nt1_A | 2isb_A (7.17%) |
2djf_B (5.68%) | |
2qgu (7.17%) |