Difference between revisions of "Canavan Disease: Task 06 - Protein Structure Prediction"

From Bioinformatikpedia
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==Dataset==
 
==Dataset==
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To gain the '''HRas''' multiple sequence alignment the instructions were followed and the full MSA provided by Pfam ([http://pfam.sanger.ac.uk/family/Ras '''PF00071''']) was downloaded and used for further calculations and statistics. Searching for a multiple sequence alignment for ASPA/ACY2 in Pfam revealed that the two criteria to gain meaningful insights out of the calculations of freecontact, evcouplings and evfold, namely over 1000 sequences in the MSA and large parts of the reference sequence are contained in the MSA, are satisfied. The multiple sequence alignment for the '''protein family containing ASPA''' ([http://pfam.sanger.ac.uk/family/PF04952 '''PF04952''']) includes '''2822 sequences''' and the region of ASPA that is used in the '''MSA spans from position 10 to 301''' with ASPA having a total length of 313 amino acids. Hence the Pfam MSA is regarded as viable input for the following calculations.
   
 
==HRAS==
 
==HRAS==

Revision as of 12:41, 18 August 2013

LabJournal

Dataset

To gain the HRas multiple sequence alignment the instructions were followed and the full MSA provided by Pfam (PF00071) was downloaded and used for further calculations and statistics. Searching for a multiple sequence alignment for ASPA/ACY2 in Pfam revealed that the two criteria to gain meaningful insights out of the calculations of freecontact, evcouplings and evfold, namely over 1000 sequences in the MSA and large parts of the reference sequence are contained in the MSA, are satisfied. The multiple sequence alignment for the protein family containing ASPA (PF04952) includes 2822 sequences and the region of ASPA that is used in the MSA spans from position 10 to 301 with ASPA having a total length of 313 amino acids. Hence the Pfam MSA is regarded as viable input for the following calculations.

HRAS

ASPA

Tasks