Talk:ASPA Sequence Alignments

It would be nice if you could add a few sentences of discussion of your results. E.g.

• What conclusion would you draw from the comparison of PSI-Blast runs (e.g. weighing compute time against result)?
• What is your conclusion concerning recall of HSSP hits?
• Which alignment would be most helpful for identifying important residues? Which would be best for modelling (-> gap placement)?

If you go a bit further in analysing your sequence hits, you will notice that your "Hepatitis C" protein is annotated in Uniprot (Q91XE4 ACY3_MOUSE) as Aspartoacylase-2. So this does make sense in your alignment.

Was Cytochrome the only structure hit you found? -- If I use HHpred online, then it finds quite a number of structures that look promising. You could have taken one in the low identity range.