Fabry:Structure-based mutation analysis

Preparation

<figtable id="tab:XXX"> ADD CAPTION HERE

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum	PDB	R-factor
1R46	X-ray	3.25	A/B	32-429	[»]	[»]	0.262
1R47	X-ray	3.45	A/B	32-429	[»]	[»]	0.285
3GXN	X-ray	3.01	A/B	32-429	[»]	[»]	0.239
3GXP	X-ray	2.20	A/B	32-429	[»]	[»]	0.204
3GXT	X-ray	2.70	A/B	32-429	[»]	[»]	0.245
3HG2	X-ray	2.30	A/B	32-429	[»]	[»]	0.178
3HG3	X-ray	1.90	A/B	32-429	[»]	[»]	0.167
3HG4	X-ray	2.30	A/B	32-429	[»]	[»]	0.166
3HG5	X-ray	2.30	A/B	32-429	[»]	[»]	0.192
3LX9	X-ray	2.04	A/B	32-429	[»]	[»]	0.178
3LXA	X-ray	3.04	A/B	32-429	[»]	[»]	0.216
3LXB	X-ray	2.85	A/B	32-429	[»]	[»]	0.227
3LXC	X-ray	2.35	A/B	32-429	[»]	[»]	0.186
3S5Y	X-ray	2.10	A/B	32-429	[»]	[»]	0.195
3S5Z	X-ray	2.00	A/B	32-429	[»]	[»]	0.211
3TV8	X-ray	2.64	A/B	32-429	[»]	[»]	0.203

</figtable>

Vizualisation

Map all the 10 mutations onto the crystal structure.

Create mutation

SCWRL