Structure-based mutation analysis (PKU)

Finding the right structure

As proposed we searched the UNIProt entry for our protein and then selected the entry with the highest resolution and the lowest r-Value. In our case this is 1J8U which is the protein in a complex with its cosubstrate BH4. IN the following we will only use this structure, if you like to have a look at all the possibilities, or try what we did on another similar example feel free to browse all our results