Homology modelling Gaucher Disease
From Bioinformatikpedia
Template selection
<figtable id="tab:ss_mapping">
| Hit Nr | Template | Identity | HHsearch prob |
|---|---|---|---|
| > 80% sequence identity | |||
| 1 | 2nt0_A | 100.0 | 100.0 |
| 40% - 80% sequence identity | |||
| < 30% sequence identity | |||
| 2 | 2wnw_A | 28.0 | 100.0 |
| 3 | 3clw_A | 14.0 | 100.0 |
| 4 | 2y24_A | 18.0 | 100.0 |
| 5 | 3kl0_A | 19.0 | 100.0 |
| 6 | 3zr5_A | 17.0 | 100.0 |
| 7 | 3ik2_A | 14.0 | 99.2 |
| 22 | 3nco_A | 11.0 | 97.7 |
</figtable>
Modeller
Results
<figtable id="tab:modeller_results">
| Template | DOPE | DOPE z-score | QMEAN6 | RMSD | TM-score | GDT_TS | GTD_HA |
|---|---|---|---|---|---|---|---|
| 2wnw_A | -55925 | -0.471 | 0.689 | 1.006 | 0.824 | 0.661 | 0.479 |
| 2y24_A | -47194 | 0.777 | 0.376 | 1.222 | 0.550 | 0.294 | 0.223 |
| 3nco_A | -44033 | 1.224 | 0.139 | 2.158 | 0.252 | 0.093 | 0.043 |
</figtable>
