Sequence-based predictions HEXA
Contents
- 1 General Information
- 2 Secondary Structure Prediction
- 3 Prediction of disordered regions
- 4 Prediction of transmembrane alpha-helices and signal peptides
- 5 Prediction of GO terms
- 6 Secondary Structure prediction
- 7 Prediction of disordered regions
- 8 Prediction of transmembrane alpha-helices and signal peptides
- 9 Prediction of GO terms
General Information
Secondary Structure Prediction
Prediction of disordered regions
Prediction of transmembrane alpha-helices and signal peptides
Prediction of GO terms
Secondary Structure prediction
Prediction of disordered regions
- Disopred
Disopred predicts two disordered regions in our protein. The first region is at the beginning of the protein (first two residues) and the second region is at the end (last three regions). This prediction is probably wrong, because it is normal, that the electrons from the first and the last amino acids lack in the electron density map. So, our protein Hexosamidase A has no disordered regions.
- POODLE
We decided to test several POODLE variants and to compare the results.
POODLE-I
POODLE-I predicted five disordered regions:
start position | end position | length |
1 | 2 | 2 |
14 | 19 | 6 |
83 | 89 | 7 |
105 | 109 | 5 |
527 | 529 | 3 |
POODLE-L
POODLE-L found no disordered regions. Therefore, there is no disordered region with a length more than 40aa in our protein.
POODLE-S (High B-factor residues)
TODO
POODLE-S predicted five disordered regions:
start position | end position | length |
0 | 2 | 2 |
13 | 19 | 7 |
83 | 88 | 6 |
105 | 109 | 5 |
526 | 529 | 4 |
POODLE-S (missing residues)
POODLE-S (missing residues) predicts regions as disordered, if there is a amino acid in the sequence record, but not on the electron density map.
Poodle-S found 6 disordered regions.
start position | end position | length |
17 | 18 | 2 |
53 | 61 | 9 |
78 | 109 | 33 |
153 | 153 | 1 |
280 | 280 | 1 |
345 | 345 | 1 |
Graphical Output:
TODO Comparison!!!