Sequence-based predictions

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Revision as of 14:39, 31 May 2011 by Landerer (talk | contribs) (GOPET)

Sequence-based predictions

1. Secondary structure prediction

PSIPRED

Jpred3

Comparison with DSSP

2. Prediction of disordered regions

DISOPRED

POODLE

IUPRED

3. Prediction of transmembrane alpha-helices and signal peptides

TMHMM

Phobius and PolyPhobius

OCTOPUS and SPOCTOPUS

SignalP

TargetP

4. Prediction of GO terms

Generel

HFE is annotated with 27 GO Terms which are:

GOID GO Term Aspect
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Process
GO:0005515 protein binding Function
GO:0005737 cytoplasm Component
GO:0005769 early endosome Component
GO:0005886 plasma membrane Component
GO:0005887 integral to plasma membrane Component
GO:0006461 protein complex assembly Process
GO:0006810 transport Process
GO:0006811 ion transport Process
GO:0006826 iron ion transport Process
GO:0006879 cellular iron ion homeostasis Process
GO:0006898 receptor-mediated endocytosis Process
GO:0006955 immune response Process
GO:0007565 female pregnancy Process
GO:0010106 cellular response to iron ion starvation Process
GO:0016020 membrane Component
GO:0016021 integral to membrane Component
GO:0019882 antigen processing and presentation Process
GO:0031410 cytoplasmic vesicle Component
GO:0042446 hormone biosynthetic process Process
GO:0042612 MHC class I protein complex Component
GO:0045177 apical part of cell Component
GO:0045178 basal part of cell Component
GO:0048471 perinuclear region of cytoplasm Component
GO:0055037 recycling endosome Component
GO:0055072 iron ion homeostasis Process
GO:0060586 multicellular organismal iron ion homeostasis Process




GOPET

Gopet predicted 2 GO-Terms which have no overlab to the annotation.

GOID Aspect Confidence GO Term
GO:0004872 Molecular Function 91% receptor activity
GO:0030106 Molecular Function 88% MHC class I receptor activity

Pfam

ProtFun 2.2