Fabry:Sequence-based analyses/Journal

Fabry Disease » Sequence-based analyses » Journal

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Quidquid latine dictum sit, altum sonatur.

- Whatever is said in Latin sounds profound.

Transmembrane helices

First we obtained the fasta sequences with the help of the bash script [ get_sequences.sh]

./[ get_sequences.sh]

With these sequences we carried out a blast search, using Polyphobius' blastget. The output we used for a multiple sequence alignment derived from Kalign and used this MSA as input for PolyPhobius. All this was done with the script [ call_polyphobius.sh]

./[ call_polyphobius.sh]

All pictures were autogenerated by the databases and programs. We executed an extra Polyphobius online search for each protein to obtain additional data and plots.