Task 5: Homology Modeling

lab journal task 5

1A6Z chain A was used as modeling target in all three methods.

Modeller

We used Modeller to create models based on a single template and multiple templates.

Single template

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<figtable id="Modeller single">

Table 1:Template structures and their sequence identity to the target, as computed by Blast.

Template	Seq. identity	std Alignment		2d alignment		curated Alignment
		GDT score	RMSD	GDT score	RMSD	GDT score	RMSD
1QVO_A	39%
1S7X_A	29%
1cd1_A	21%

</figtable>

<xr id="Modeller single"/> list the selected templates and the results of the different

MSA:

"close" homology
1rjz_D	0.34
1zag_A	0.36
1QVO_A	0.39

distant homology:
3huj_C	0.23
1cd1_A	0.21
1VZY_A	0.14

MIX:

1cd1_A 0.21

1QVO_A 0.39