Structure-based mutation analysis BCKDHA

Structure selection

The following table presents the PDB structures for BCKDHA to date:

PDB id	resolution [Å]	R-factor	coverage	ph-value
1DTW	2.70	0.224		7.5*
1OLS	1.85	0.172		5.5
1OLU	1.90	0.161		5.5
1OLX	2.25	0.161		5.5
1U5B	1.83	0.156		5.8
1V11	1.95	0.139*		5.5
1V16	1.90	0.132*		5.5
1V1M	2.00	0.130*		5.5
1V1R	1.80	0.158		5.5
1WCI	1.84	0.149		5.5
1X7W	1.73	0.148		5.8
1X7X	2.10	0.149		5.8
1X7Y	1.57	0.150		5.8
1X7Z	1.72	0.154		5.8
1X80	2.00	0.161		5.8
2BEU	1.89	0.171		5.5
2BEV	1.80	0.139		5.5
2BEW	1.79	0.147		5.5
2BFB	1.77	0.145		5.5
2BFC	1.64	0.144		5.5
2BFD	1.39*	0.150		5.5
2BFE	1.69	0.150		5.5
2BFF	1.46	0.150		5.5
2J9F	1.88	0.171		5.5

The following PDB Structure was chosen because of its good experimental resolution: <bold></bold>

• resultion:
• R-factor
• ph-value

Gromacs

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