Difference between revisions of "Task 8: Sequence-based mutation analysis"

From Bioinformatikpedia
(→‎Mutation selection)
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[[Lab journal task 8]]
  
[[Lab journal task 8]]
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== Mutation selection ==
  
== Mutation selection ==
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! nucleotide change || amino acid change
  
! nucleotide change || amino acid change
 
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| || Val53Met
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| || Val53Met
 
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| || His63Asp
 
| || His63Asp
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== Mutation analysis ==
  
== Mutation analysis ==
   
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<figtable id="summary>
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'''Val53Met'''
  
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<figtable id="Val53Met">
  
 
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{|class="colBasic2"
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!pyhsicochemical properties || pymol visualisation || secondary structure || substitution matrix || PSSM || MSA || SIFT || Polyphen2 || MutationTaster || SNAP
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! reference || mutation || pyhsicochemical properties || pymol visualisation || secondary structure || substitution matrix || PSSM || MSA || SIFT || Polyphen2 || MutationTaster || SNAP || consensus
 
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|-
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| || Val53Met
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|+ style="caption-side: bottom; text-align: left" |<font size=2>'''Table 2:''' Summary of the analysis of Val53Met.
  
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|}
  
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</figtable>
  
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''' His63Asp '''
  
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<figtable id="His63Asp">
  
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| || His63Asp
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|+ style="caption-side: bottom; text-align: left" |<font size=2>'''Table 2:''' Summary of the analysis of His63Asp.
  
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|}
  
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</figtable>
  
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''' Arg67His '''
  
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<figtable id="His63Asp">
  
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| || Arg67His
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|+ style="caption-side: bottom; text-align: left" |<font size=2>'''Table 2:''' Summary of the analysis of His63Asp.
  
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|}
  
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</figtable>
  
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''' Met97Ile '''
  
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<figtable id="His63Asp">
  
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| || Met97Ile
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|+ style="caption-side: bottom; text-align: left" |<font size=2>'''Table 2:''' Summary of the analysis of His63Asp.
  
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|}
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|-
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| || Asn130Ser
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</figtable>
  
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| || Glu168Gln
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''' Asn130Ser '''
  
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| || Leu183Pro
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<figtable id="His63Asp">
  
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| || Thr217Ile
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| || Cys282Tyr
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| || Arg330Met
 
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|+ style="caption-side: bottom; text-align: left" |<font size=2>'''Table 2:''' Summary of the analysis of His63Asp.
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|+ style="caption-side: bottom; text-align: left" |<font size=2>'''Table 2:''' Summary of the analysis for all mutations.
 
|}
  
|}
 
</figtable>
  
</figtable>
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''' Glu168Gln '''
  
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''' Leu183Pro '''
  
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''' Thr217Ile '''
  
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''' C282Y '''
  
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''' Arg330Met '''
  

Revision as of 15:57, 22 August 2013

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Lab journal task 8

Mutation selection

<figtable id="mutations">

mutations
nucleotide change amino acid change
Val53Met
His63Asp
Arg67His
Met97Ile
Asn130Ser
Glu168Gln
Leu183Pro
Thr217Ile
Cys282Tyr
Arg330Met
Table 1: List of the 10 selected mutations from HGMD and dbSNP.

</figtable>


Mutation analysis

<figtable id="summary>

reference mutation pyhsicochemical properties pymol visualisation secondary structure substitution matrix PSSM MSA SIFT Polyphen2 MutationTaster SNAP consensus
Val53Met
His63Asp
Arg67His
Met97Ile
Asn130Ser
Glu168Gln
Leu183Pro
Thr217Ile
Cys282Tyr
Arg330Met
Table 2: Summary of the analysis for all mutations.

</figtable>

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