Difference between revisions of "Task 9 (MSUD)"

From Bioinformatikpedia
m (Results)
m (Visualization of mutant structures)
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===Visualization of mutant structures===
 
===Visualization of mutant structures===
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The mutagen tool of PyMOL was used to introduce mutations to the protein structure. Mutations and their neighboring residues are visualized and shown in following figures.
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<gallery caption="Visualization of mutations in BCKDHA (2BFF)" widths="300" heights="300" perrow=3>
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File:2bff_m82l.png
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File:2bff_a222t.png
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File:2bff_c264w.png
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File:2bff_r346h.png
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File:2bff_i361v.png
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</gallery>
   
 
===Mutant structures (SCWRL)===
 
===Mutant structures (SCWRL)===

Revision as of 12:01, 12 July 2013

Results

Lab journal

For this task we have chosen 5 mutations from HGMD and dbSNP. 2 of them are neutral mutations which do not have functional changes over the protein structure. Following are the 5 mutations: TODO: TABLE

Visualization of mutant structures

The mutagen tool of PyMOL was used to introduce mutations to the protein structure. Mutations and their neighboring residues are visualized and shown in following figures.

Mutant structures (SCWRL)

Energy comparisons

FoldX

Minimise

Gromacs