Normal mode analysis Gaucher Disease

Introduction

Technical details are reported in our protocol

WEBnm@

Deformation Energies

"Deformation energies and eigenvalues reflect the energy associated with each mode and are inversely related to the amplitude of the motion described by a the corresponding modes. The protein structure moves along all the normal modes at once. A mode should only be interpreted in isolation if it is energetically well separated from other modes. " - from Webnma@

Below are the values of the deformation energy for modes 7 to 20.

<figtable id="tab:defor_enery">

Mode Index	Deformation Energy	Mode Index	Deformation Energy
7	1663.91	14	6698.31
8	2377.48	15	9791.69
9	2720.71	16	9534.10
10	5191.86	17	10022.74
11	5033.67	18	11137.44
12	6174.70	19	11592.80
13	6360.72	20	12045.03

The deformation energy for modes 7 to 20 for protein structure 2NT0 chain A from Webnma@. </figtable>

<figure id="fig:Eingenvalues_plot">

The Eigenvalues Plot for for protein structure 2NT0 chain A from Webnma@.

</figure>