Difference between revisions of "Task6-MSUP-journal"

From Bioinformatikpedia
(→‎PSI-BLAST - PSSM)
(→‎PSI-BLAST - PSSM)
 
Line 458: Line 458:
 
PSI Ungapped 0.1713 0.3175
  
PSI Ungapped 0.1713 0.3175
 
PSI Gapped 0.0524 0.2670
  
PSI Gapped 0.0524 0.2670
  +
  +
  +
CLUSTAL 2.0.12 multiple sequence alignment
  +
  +
  +
gi|39943658|ref|XP_361366.1| ----MR--VRLPGAASSIGR---RCRNHGR--------------------
  +
gi|164422564|ref|XP_960181.2| ----MKRICRSSQRSPSLLRPLTPVTHQPR--------------------
  +
gi|21355903|ref|NP_649905.1| ---------------MSFLRKSVHLLGS----------------------
  +
gi|158291301|ref|XP_312823.4| -------------------------LSS----------------------
  +
gi|11386135|ref|NP_000700.1| --------MAVAIAAARVWRL-NRGLSQ----------------------
  +
gi|148727347|ref|NP_001092034. --------MAVAIAAARVWRL-NRGLSQ----------------------
  +
gi|297277135|ref|XP_001101959. --------MAVAIAAARVWRP-NRGLSQ----------------------
  +
gi|73947481|ref|XP_866392.1| --------MAVAAAAARVWGS-SRGLGQ----------------------
  +
gi|27806229|ref|NP_776931.1| MQGSAKMAMAVAVAVARVWRP-SRGLGR----------------------
  +
gi|183396774|ref|NP_031559.3| --------MAIVMSAAKIWRP-SRGLRQ----------------------
  +
gi|77736548|ref|NP_036914.1| --------MAVAMSAAKIWRP-SRGLRQ----------------------
  +
gi|66773104|ref|NP_001019590.1 --------MAAARAVKKLYGIGLHAIRQN---------------------
  +
gi|86563355|ref|NP_001033376.1 -------------------------MHR----------------------
  +
gi|18415939|ref|NP_568209.1| ----MALHLRSSFSSKSTLLNILRHNLGFGSRSHVTR--------HIRQI
  +
gi|115487674|ref|NP_001066324. ----MAPWRAAAMASSQLARRAARRLLSSQHRRHCAAPACPWLLGSAPPV
  +
  +
  +
gi|39943658|ref|XP_361366.1| --------GAP-KIGSLHQTAPGSASSMRAASTLKQKP-----DSSFVSF
  +
gi|164422564|ref|XP_960181.2| --------LVPIAIQPSTTTTSKTVASRRHASSLSQRP-----DASHVMF
  +
gi|21355903|ref|NP_649905.1| ------------VARRQRHLKVIEGAISTAARDFSSKP-----SEDYANF
  +
gi|158291301|ref|XP_312823.4| ------------DAASQ--------------QQGASGP-----SSLHAKF
  +
gi|11386135|ref|NP_000700.1| --------AALLLLRQPGARGLARSHPPR--QQQQFSS-----LDDKPQF
  +
gi|148727347|ref|NP_001092034. --------AALLLLRRPGARGLARSHPRR--QQQQFSS-----LDDKPQF
  +
gi|297277135|ref|XP_001101959. --------AALLLLWRPGARGLARSHPHR--QQQQFSS-----LDDKPQF
  +
gi|73947481|ref|XP_866392.1| --------AGLLLLRRPWARGLARSHPQR-QEQQHFPS-----LDDKPQF
  +
gi|27806229|ref|NP_776931.1| --------TGLPLLRLLGARGLARFHPHRWQQQQHFSS-----LDDKPQF
  +
gi|183396774|ref|NP_031559.3| --------AALLLLGRSGVRGLARSHPSR-QQQQQFPS-----LDDKPQF
  +
gi|77736548|ref|NP_036914.1| --------AALLLLGRPGARGLARFHPSR-QQQQQFPS-----LDDKPQF
  +
gi|66773104|ref|NP_001019590.1 --------TALKATTLLQQRGFRVNGVLR---QQSIDD-----SDEKPQF
  +
gi|86563355|ref|NP_001033376.1 --------ALLNASRRVATVRSMASTVEG----DAFRL-----SEYSSKY
  +
gi|18415939|ref|NP_568209.1| LPHDPPLRGSQNPISRLCNT---MAEPETLSSFVQHEY---ANNHQVMDF
  +
gi|115487674|ref|NP_001066324. LAPSPVAAAAAGDRRGFCSVRRFTGESNAAAAVEEAENGLVAGGDQAIDF
  +
:
  +
  +
gi|39943658|ref|XP_361366.1| PGAVKSEFTTKFQFERPEQYPAMPTYRVVDQHGVVVDPEFEQDLNDEGVI
  +
gi|164422564|ref|XP_960181.2| PGAVKSAFCNTMTFEEPSKYDALPTYRAVDQHGQVVDPSFKPDLSDKEVI
  +
gi|21355903|ref|NP_649905.1| PGA-KAPFVSKLNLIQPEDYAPIPIYRVMDQDGYIADETQDPQLGREVVE
  +
gi|158291301|ref|XP_312823.4| PGALEASFVTTPKLALPESIEPIPIYRVMNSEGVIDDPSQEPNLEQATVQ
  +
gi|11386135|ref|NP_000700.1| PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVL
  +
gi|148727347|ref|NP_001092034. PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVL
  +
gi|297277135|ref|XP_001101959. PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVL
  +
gi|73947481|ref|XP_866392.1| PG-ASAEFIDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQEKVL
  +
gi|27806229|ref|NP_776931.1| PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVL
  +
gi|183396774|ref|NP_031559.3| PG-ASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVL
  +
gi|77736548|ref|NP_036914.1| PG-ASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVL
  +
gi|66773104|ref|NP_001019590.1 PG-ASAEFIDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPQLSKETVL
  +
gi|86563355|ref|NP_001033376.1 LGHRKAAFTEKLEIVNADDTPALPIYRVTNAVGDVIDKSQDPNFDEQTSL
  +
gi|18415939|ref|NP_568209.1| PG-GKVAFTPEIQFISESDKERVPCYRVLDDNGQLITNSQFVQVSEEVAV
  +
gi|115487674|ref|NP_001066324. PG-GKVSFVAEMNFLPESQRDRINCYRVLDDDGRTISGSRFQEVSKELAL
  +
* . * : . : **. : * ..
  +
  +
gi|39943658|ref|XP_361366.1| KLYEDMVAVSVMDSIMFDAQRQGRVSFYMVSAGEEAVCVGSASALEMRDV
  +
gi|164422564|ref|XP_960181.2| KLYHDMLTVSIMDLIMFDAQRQGRLSFYMVSAGEEAVCVGSASALSPEDV
  +
gi|21355903|ref|NP_649905.1| KMFRDMVLLNTMDKILYESQRQGRISFYMTNFGEEASHIGSAAALEMRDL
  +
gi|158291301|ref|XP_312823.4| KMFRDMVLLNTMDKILYESQRQGRISFYMTNFGEEASHIGSAAALSLEDW
  +
gi|11386135|ref|NP_000700.1| KLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
  +
gi|148727347|ref|NP_001092034. KLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
  +
gi|297277135|ref|XP_001101959. KLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
  +
gi|73947481|ref|XP_866392.1| KFYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
  +
gi|27806229|ref|NP_776931.1| KFYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDL
  +
gi|183396774|ref|NP_031559.3| KFYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDL
  +
gi|77736548|ref|NP_036914.1| KLYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDL
  +
gi|66773104|ref|NP_001019590.1 NFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHIGSAAALDPSDL
  +
gi|86563355|ref|NP_001033376.1 KMYKTMTQLNIMDRILYDSQRQGRISFYMTSFGEEGNHVGSAAALEPQDL
  +
gi|18415939|ref|NP_568209.1| KIYSDMVTLQIMDNIFYEAQRQGRLSFYATAIGEEAINIASAAALTPQDV
  +
gi|115487674|ref|NP_001066324. KMYNEMATLQVMDTIFFEAQRQGRISFYLTSHGEEAINIASAAALTIDDI
  +
::: * :. ** *::::*****:*** . ***. :.**:** *
  +
  +
gi|39943658|ref|XP_361366.1| IFCQYREQGVYRHRGMTFRDFMNQLFANKYDPGQGRNMPVHYGSKELNMH
  +
gi|164422564|ref|XP_960181.2| VFCQYREQGVFKQRGFQLSDFMNQLFANHKDSGKGRNMPVHYGSKELNIH
  +
gi|21355903|ref|NP_649905.1| IYGQYREAGVLVWRGFRIDQFIDQCYGNTDDLGRGKQMPVHYGSRELNFV
  +
gi|158291301|ref|XP_312823.4| VYGQYREAGVLVWRGFTISDFINQCYGNAEDQGKGRQMPVHYGSRKLNFV
  +
gi|11386135|ref|NP_000700.1| VFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFV
  +
gi|148727347|ref|NP_001092034. VFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFV
  +
gi|297277135|ref|XP_001101959. VFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFV
  +
gi|73947481|ref|XP_866392.1| VFGQYREAGVLMYRDYPLELFMAQCYGNVSDPGKGRQMPVHYGCKDRHFV
  +
gi|27806229|ref|NP_776931.1| VFGQYREAGVLMYRDYPLELFMAQCYGNVSDLGKGRQMPVHYGCRERHFV
  +
gi|183396774|ref|NP_031559.3| VFGQYREAGVLMYRDYPLELFMSQCYGNVNDPGKGRQMPVHYGCKERHFV
  +
gi|77736548|ref|NP_036914.1| VFGQYREAGVLMYRDYPLELFMAQCYGNVSDPGKGRQMPVHYGCKERHFV
  +
gi|66773104|ref|NP_001019590.1 VFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGSKDLNFV
  +
gi|86563355|ref|NP_001033376.1 IYGQYREAGVLLWRGYTMENFMNQCYGNADDLGKGRQMPMHFGTKERNFV
  +
gi|18415939|ref|NP_568209.1| IFPQYREPGVLLWRGFTLQEFANQCFGNKSDYGKGRQMPVHYGSNKLNYF
  +
gi|115487674|ref|NP_001066324. VLPQYREPGVLLWRGFTLQEFANQCFGNKLDYGKGRQMPIHYGSNRLNYF
  +
: **** ** *. : * * :.* * *:*::**:*:* . :
  +
  +
gi|39943658|ref|XP_361366.1| TISSPLATQIPQASGAAYAMKMQRIANPDAPERVAVVYFGEGAASEGDFH
  +
gi|164422564|ref|XP_960181.2| TISSPLATQLPQAAGAAYALKIQRMQNPTVPPRVVAAYFGEGAASEGDFH
  +
gi|21355903|ref|NP_649905.1| TISSPLSTQMPQAVGAAYAMKLRPNND-----ACVVCYFGEGAASEGDAH
  +
gi|158291301|ref|XP_312823.4| TISSPLGTQIPQAAGAAYAFKLQPNNQ-----RCVITYFGEGAASEGDTH
  +
gi|11386135|ref|NP_000700.1| TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
  +
gi|148727347|ref|NP_001092034. TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
  +
gi|297277135|ref|XP_001101959. TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
  +
gi|73947481|ref|XP_866392.1| TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
  +
gi|27806229|ref|NP_776931.1| TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
  +
gi|183396774|ref|NP_031559.3| TISSPLATQIPQAVGAAYAAKRA-NAN-----RIVICYFGEGAASEGDAH
  +
gi|77736548|ref|NP_036914.1| TISSPLATQIPQAVGAAYAAKRA-NAN-----QIVICYFGEGAASEGDAH
  +
gi|66773104|ref|NP_001019590.1 TISSPLATQIPQAAGAAYAVKRE-NAN-----RVVICYFGEGAASEGDAH
  +
gi|86563355|ref|NP_001033376.1 TISSPLTTQLPQAVGSAYAFKQQKDNN-----RIAVVYFGDGAASEGDAH
  +
gi|18415939|ref|NP_568209.1| TVSATIATQLPNAVGAAYSLKMD-KKD-----ACAVTYFGDGGTSEGDFH
  +
gi|115487674|ref|NP_001066324. TVSSPIATQLPHAVGAAYSLKMD-KKD-----ACAITYFGDGGTSEGDFH
  +
*:*:.: **:*:* *:**: * : . ***:*.:**** *
  +
  +
gi|39943658|ref|XP_361366.1| AALNIAATRACPVIFICRNNGYSISTPSLEQYKGDGIASR-GVGYGIDTV
  +
gi|164422564|ref|XP_960181.2| AALNIAATRGCPAVFICRNNGYAISTPTLEQYRGDGIASR-GLGYGIETI
  +
gi|21355903|ref|NP_649905.1| AAFNFAATLGCPAILFCRNNGFAISTPSHEQYKGDGIAGRGPMGYGITTI
  +
gi|158291301|ref|XP_312823.4| AAFNFAATLDSPVIFFCRNNGFAISTPSKEQYRGDGIAGR-AAGYGMAAL
  +
gi|11386135|ref|NP_000700.1| AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
  +
gi|148727347|ref|NP_001092034. AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
  +
gi|297277135|ref|XP_001101959. AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAR--GPGYGIMSI
  +
gi|73947481|ref|XP_866392.1| AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
  +
gi|27806229|ref|NP_776931.1| AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGILSI
  +
gi|183396774|ref|NP_031559.3| AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
  +
gi|77736548|ref|NP_036914.1| AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
  +
gi|66773104|ref|NP_001019590.1 AGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAAR-GPGYGLMSI
  +
gi|86563355|ref|NP_001033376.1 AAFNFAATLKCPIIFFCRNNGYAISTPTSEQYGGDGIAGK-GPAYGLHTI
  +
gi|18415939|ref|NP_568209.1| AALNIAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVK-GRAYGIRSI
  +
gi|115487674|ref|NP_001066324. AALNFAAVMEAPVIFFCRNNGWAISTPTSEQFRSDGAVIR-GQAYGMRSI
  +
*.:*::*. .* :::*****::****: :*: .** . .**: ::
  +
  +
gi|39943658|ref|XP_361366.1| RVDGNDIWAVRKATKKARELALENGGKPVLLECLTYRVGHHSTSDDSFAY
  +
gi|164422564|ref|XP_960181.2| RVDGNDFWAVREVTKRARELALQDGGKPVLIEAMTYRVSHHSTSDDSFAY
  +
gi|21355903|ref|NP_649905.1| RVDGTDVFAVYNAMKAAREYVLKE-NKPVVFEALAYRVGHHSTSDDSTAY
  +
gi|158291301|ref|XP_312823.4| RFDGTDVFATYNATKLAREYVLRE-NKPIVLEAMAYRIGHHSTSDDSTAY
  +
gi|11386135|ref|NP_000700.1| RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|148727347|ref|NP_001092034. RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|297277135|ref|XP_001101959. RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|73947481|ref|XP_866392.1| RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|27806229|ref|NP_776931.1| RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|183396774|ref|NP_031559.3| RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|77736548|ref|NP_036914.1| RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|66773104|ref|NP_001019590.1 RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
  +
gi|86563355|ref|NP_001033376.1 RVDGNDLLAVYNATKEARRVALT--NRPVLIEAMTYRLGHHSTSDDSTAY
  +
gi|18415939|ref|NP_568209.1| RVDGNDALAMYSAVHTAREMAIRE-QRPILIEALTYRVGHHSTSDDSTRY
  +
gi|115487674|ref|NP_001066324. RVDGNDALAVYSAVHTAREMAIKE-GRPILVEALTYRVGHHSTSDDSTKY
  +
*.**.* * .. : **. .: :*.:.*.::**:.******** *
  +
  +
gi|39943658|ref|XP_361366.1| RARVEVEDWKRRDNPISRLRKWMESKDMWDDDKEKVMRDRLRKEILKAFS
  +
gi|164422564|ref|XP_960181.2| RAKVEVEDWKRRDNPIGRLRKWMEAKGIWDENMEREARDSIRRDILKAFS
  +
gi|21355903|ref|NP_649905.1| RPAEEIEIWNSVEHPISKLKRYMVHKGWFDETVENEYVKDIRKKVLKQIA
  +
gi|158291301|ref|XP_312823.4| RPAEELEVWNTVEHPIAKLKHYMLRRGWFDEAKENEFVKSVRKQVLSQIN
  +
gi|11386135|ref|NP_000700.1| RSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFE
  +
gi|148727347|ref|NP_001092034. RSVDEVNYWDKQDHPVSRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFE
  +
gi|297277135|ref|XP_001101959. RSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFE
  +
gi|73947481|ref|XP_866392.1| RSVDEVNYWDKQDHPISRLRHYLQSRGWWDDEQEKAWRKQSRKKVMEAFE
  +
gi|27806229|ref|NP_776931.1| RSVDEVNYWDKQDHPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFE
  +
gi|183396774|ref|NP_031559.3| RSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFE
  +
gi|77736548|ref|NP_036914.1| RSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFE
  +
gi|66773104|ref|NP_001019590.1 RSVDEVNYWDKQDHPISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFE
  +
gi|86563355|ref|NP_001033376.1 RSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEMEWQKEVKKRVLTEFA
  +
gi|18415939|ref|NP_568209.1| RSAGEIEWWNKARNPLSRFRTWIESNGWWSDKTESDLRSRIKKEMLEALR
  +
gi|115487674|ref|NP_001066324. RPVDEIEHWRTARDPISRYRKWVQGNGWWCDEDESELRNNVRQELLKAIQ
  +
*. *:: * .*: : : : .. : : * . :: :: :
  +
  +
gi|39943658|ref|XP_361366.1| EAEKEKKPPIRAMFEDVYEEMTPDLKKQMAELKDHIERYPEEYD-VGEFE
  +
gi|164422564|ref|XP_960181.2| QAEKEKKPAIRTMFEDVYEEMTPEIKAQMKELKEHLEQYPEEYD-LGDFE
  +
gi|21355903|ref|NP_649905.1| VSEKKLKPNWREMFEGVYAEMPDHLIEQRSELEKHIEAHKEHYP-LKDFE
  +
gi|158291301|ref|XP_312823.4| QSERILKPDWREMFQDVYAEMPAHLKEQLRAMEEHVEQHREHYP-LKDFK
  +
gi|11386135|ref|NP_000700.1| QAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LDHFD
  +
gi|148727347|ref|NP_001092034. QAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LDHFD
  +
gi|297277135|ref|XP_001101959. QAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LEHFD
  +
gi|73947481|ref|XP_866392.1| QAERKPKPNPNLLFSDVYQEMPTQLRKQQEALARHLQTYGEHYP-LDHFE
  +
gi|27806229|ref|NP_776931.1| QAERKLKPNPSLIFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LDHFE
  +
gi|183396774|ref|NP_031559.3| QAERKLKPNPSLLFSDVYQEMPAQLRRQQESLARHLQTYGEHYP-LDHFD
  +
gi|77736548|ref|NP_036914.1| QAERKLKPNPSLLFSDVYQEMPAQLRRQQESLARHLQTYGEHYP-LDHFD
  +
gi|66773104|ref|NP_001019590.1 RAERRLKPNPDLMFTDVYDEMVPHIAKQKDSMWRHVQQYKEHYP-LDHYE
  +
gi|86563355|ref|NP_001033376.1 AAEKRKKAHYHDLFEDVYDELPLRLRRQRDELDAHVAEYKEHYPMLETLQ
  +
gi|18415939|ref|NP_568209.1| VAEKTEKPNLQNMFSDVYDVPPSNLREQELLVRQTINSHPQDYP--SDVP
  +
gi|115487674|ref|NP_001066324. VAERMPKPPLAELFTDVYDEVPSNLREQERLLRDTIKKHPADYP--ADVH
  +
:*: *. :* .** : * : : : .*
  +
  +
gi|39943658|ref|XP_361366.1| GGKDSLKP
  +
gi|164422564|ref|XP_960181.2| GGKDSLAR
  +
gi|21355903|ref|NP_649905.1| K-------
  +
gi|158291301|ref|XP_312823.4| Q-------
  +
gi|11386135|ref|NP_000700.1| K-------
  +
gi|148727347|ref|NP_001092034. K-------
  +
gi|297277135|ref|XP_001101959. K-------
  +
gi|73947481|ref|XP_866392.1| K-------
  +
gi|27806229|ref|NP_776931.1| K-------
  +
gi|183396774|ref|NP_031559.3| K-------
  +
gi|77736548|ref|NP_036914.1| K-------
  +
gi|66773104|ref|NP_001019590.1 K-------
  +
gi|86563355|ref|NP_001033376.1 SKP-----
  +
gi|18415939|ref|NP_568209.1| L-------
  +
gi|115487674|ref|NP_001066324. I-------

Latest revision as of 14:42, 18 June 2012

PSI-BLAST - PSSM

Command: 

 blastpgp -i ref_seq_BCKDHA.fas -d /mnt/project/rost_db/data/big/big -j 5 -Q BCKDHA.pssm -o blast.out


Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts 

          A  R  N  D  C  Q  E  G  H  I  L  K  M  F  P  S  T  W  Y  V   A   R   N   D   C   Q   E   G   H   I   L   K   M   F   P   S   T   W   Y   V
   1 M   -2 -3 -4 -5 -3 -2 -4 -4 -3  0  3 -3  8 -1 -4 -3 -2 -3 -2  1    0   0   0   0   0   0   0   0   0   0  27   0  63   0   0   0   0   0   0  10  1.00 inf
   2 A    3 -2 -1 -2 -2 -2 -2  1 -2 -3 -2 -2 -2 -3  2  3  1 -4 -3 -2   39   0   2   0   0   0   0   8   0   0   2   0   0   0   8  31  10   0   0   0  0.46 inf
   3 V    1  1 -2 -3 -2 -2 -2 -2 -2  1  1 -1  0  1  1  1 -1 -3 -1  1   17  13   0   0   0   0   0   0   0  10  19   0   0   9   7  13   2   0   0  11  0.13 inf
   4 A    1 -1 -2 -3 -2 -1 -2 -2 -3  0  2 -2  0 -1  2  2  0 -3 -2  0   17   3   0   0   0   2   0   0   0   1  31   0   0   1  12  24   4   0   0   5  0.25 inf
   5 I   -1  3 -2 -3 -3 -1 -2 -2 -2  2  2 -1  0  2 -3 -1 -1 -3 -1  0    5  30   0   0   0   1   0   3   0  17  24   1   1  10   0   6   1   0   0   1  0.24 inf
   6 A    0  2  0 -2 -1  0  0 -1  0  0  0  1 -1 -2 -1  2  1 -3 -1 -1    9  19   2   0   1   1   3   4   3   6  10   8   0   0   1  25   7   0   1   0  0.15 inf
   7 A    2  1 -2 -2  1  0  0  0 -2 -1 -1 -1  0 -3  1  1  1 -3 -3 -1   31  11   0   0   3   3   8   6   0   2   6   0   4   0   7  11   9   0   0   1  0.19 inf
   8 A    0  1  0 -2  1 -2 -2 -1 -2  0 -2 -1 -2 -3  5  1  1 -4 -3  0   10  11   4   0   3   0   0   5   0   8   1   2   0   0  30  10   8   0   0   9  0.41 inf
   9 R    2  4 -1 -3  2  0 -2 -2 -2  0  0  1 -1 -3  0 -1 -1 -3 -2  0   23  32   2   0   6   2   0   0   0   5  10   5   0   0   4   1   3   0   0   5  0.27 inf
  10 V   -2 -1 -3 -4  2 -3 -3 -1 -3  2  2 -3  2  2 -2 -2 -2  0 -1  2    0   3   0   0   6   0   0   5   0  13  27   0   6  12   2   3   0   1   0  23  0.27 inf
  11 W    1  2 -2 -2  0 -1 -2  0  1  0  0 -1 -1 -2 -2  1  0  4  0 -1   18  15   0   1   2   1   0   5   4   7  14   0   0   0   1  16   5   8   2   1  0.15 inf
  12 R    0  4  0 -2 -3  1  1  1  2 -2 -1  0 -2 -3  1 -1 -1 -4 -2 -2    8  31   4   0   0   4   8  13   7   3   7   3   0   0   6   2   2   0   0   1  0.25 inf
  13 L    0  0 -2 -2 -2 -1 -2 -2  1  0  1 -1  1 -2  2  2  0  2 -1  0    6   6   0   0   0   2   0   2   6   7  18   2   5   0  10  22   3   3   1   8  0.13 inf
  14 N    1  1  1  0 -1  0 -1  0 -2 -2  0  0 -1 -3  2  2  1 -3 -2 -1    9   9   9   4   1   3   0   4   0   0  10   5   0   0  11  20  10   0   1   4  0.17 inf
  15 R    0  5  0 -2 -1  1 -1 -1 -1 -1 -1  0 -2 -3 -2  1  0 -4 -3 -1    8  43   3   0   1   7   0   3   1   5   4   2   0   0   1  12   4   0   0   3  0.40 inf
  16 G    0  0 -1 -2 -3 -1 -2  3  3 -2 -2  0 -2 -2  3  1 -1 -4 -2 -1    7   4   2   0   0   2   0  28   9   1   3   5   1   2  16  14   2   0   0   5  0.33 inf
  17 L    1  1 -2 -2 -2 -1 -1 -2  0  0  2 -2  1  1  0 -1 -1  0  0  1   13   9   0   2   0   2   3   2   3   3  31   0   2   9   4   2   1   1   1  12  0.10 inf
  18 S    0  3 -1 -2 -2  2 -1 -1  2 -2 -1  0 -1 -2  1  2  1 -3 -1 -1    8  19   1   0   1  12   0   4   8   0   6   2   1   1   8  17   8   0   1   3  0.21 inf
  19 Q    0  3  0 -2 -3  2 -1 -2 -1 -2 -1  1 -2  2  0  1  0 -3 -1 -2   11  18   5   0   0  14   0   1   1   1   5   9   0  15   5   9   5   0   0   2  0.20 inf
  20 A    2 -1 -1 -2 -2 -1 -2 -1 -2  0  1 -1  1 -2  0  1  0 -3 -1  1   28   4   3   0   0   2   0   1   1   5  14   2   5   0   5  16   2   0   2   9  0.14 inf
  21 A    1  2 -1 -2  1  0 -1  0 -1 -1 -1  0 -1 -2  2  2  0 -3 -2 -1   14  15   0   0   4   4   2   5   1   4   6   2   1   1  11  22   5   0   1   2  0.19 inf
  22 L    0  1 -1 -2  2 -1 -2 -1  1 -1  1  0  0  0  3  0 -1 -3 -2 -1   11   8   3   0   7   1   0   4   6   3  17   5   1   5  17   8   2   0   0   3  0.16 inf
  23 L    1  1  1 -1  1  1 -1 -1  1  0  0  0 -1 -2  2  0  0 -3 -2  0   13  11   9   2   3   7   0   3   4   4  11   2   1   1  11   6   3   0   0  10  0.10 inf
  24 L    0  0 -1 -1 -1 -1 -1 -2  1  0  2  0  0  0 -2  0  1 -2  0  0   10   7   1   4   1   2   2   2   4   4  28   5   0   2   0  10   9   0   3   5  0.06 inf
  25 L    0  0 -1 -2 -1 -1 -1 -1 -1  0  2 -1  2  0  2 -1  0  0 -1  0    9   7   2   0   1   3   2   5   1   4  25   3   7   5  11   4   3   1   0   6  0.09 inf
  26 R    0  4  0 -2 -3  0 -1 -1  1 -1 -2  1 -2 -3 -1  2  1 -4 -2 -2    9  33   4   0   0   2   1   2   3   5   1   5   0   0   2  23   8   0   1   0  0.36 inf
  27 Q   -1  2  0  1 -3  0  0 -1  0 -1 -1  0 -1 -2  1  1  1  0 -2  0    2  20   3   7   0   5   2   5   2   3   6   4   0   2   6  10  14   1   0   8  0.12 inf
  28 P    1  0  0 -1 -1 -1 -1  0 -2 -1 -1  0 -1 -1  3  2  1 -3 -2  0   15   6   4   3   1   1   1   7   0   1   7   4   2   2  15  18   8   0   0   6  0.18 inf
  29 G    2  1 -1 -2  0 -1 -1  2 -1 -1 -1 -1  0 -1 -2  1  0 -3 -2  0   24  10   2   1   2   2   1  16   1   5   4   2   4   3   1  14   6   0   0   5  0.14 inf
  30 A    1  0  2 -1 -2  1  0  1  0 -1 -1  0  0 -3  0  1  1 -3 -2  0   15   3  13   1   0   8   3  10   2   4   4   4   2   0   3  14   7   0   0   7  0.12 inf
  31 R    0  3  0 -2  2  0 -1 -1  1 -1  0  0  0  0  0  1  0  0  1 -1    6  22   3   1   5   3   1   3   3   1  15   4   1   3   5  11   3   1   5   2  0.11 inf
  32 G   -1  0  1 -2 -1 -1 -2  2 -1 -2 -1 -1 -2 -3  4  1  1  1 -2 -1    2   8   6   0   1   1   1  20   1   1   6   2   0   0  20  13   9   3   1   5  0.30 inf
  33 L    1 -1 -1 -2 -2  0  1 -2 -2 -1  1 -1 -1 -1  3  1  1 -3 -2 -1   12   3   1   0   0   3   9   1   1   3  19   3   1   2  19  10  12   0   1   2  0.23 inf
  34 A    1 -2 -2 -3 -1 -2 -2 -2 -1 -1  2 -2  0  0  3  1  0 -1 -2 -1   18   0   1   0   1   1   2   1   2   2  34   1   1   3  14  11   6   1   0   1  0.26 inf
  35 R    0  5 -1 -2 -3  0  0 -2 -1 -3 -2  1 -2 -3 -3  1 -1  0 -2 -2    7  47   2   0   0   3   3   2   1   1   4   7   0   1   1  15   2   1   1   2  0.54 inf
  36 S    0 -1 -2 -1  0 -1 -1 -2 -1 -1  2 -1  0  0  3  2  0 -3 -2 -1    5   4   1   3   2   1   2   2   2   2  28   2   1   3  15  20   7   0   0   2  0.21 inf
  37 H    0 -1  0  0 -1 -1  0 -2  7 -2 -2 -2 -2 -1 -2 -1  0  1  1  0    7   3   3   5   1   2   6   1  38   1   3   1   0   2   1   4   7   2   5   7  0.51 inf
  38 P    1  0 -1 -2 -1 -1 -1 -1 -1  0 -1 -1 -1 -1  3  0 -1 -4 -2  3   11   7   2   1   1   1   2   3   1   4   2   3   0   3  18   9   2   0   0  30  0.25 inf
  39 P   -2  3 -1 -1 -2 -1 -1 -2 -2 -2 -1 -1 -2 -4  5  1  0  1 -3 -1    1  20   2   2   1   0   4   2   0   2   5   2   0   0  35  11   6   2   0   4  0.61 inf
  40 R    0  3 -1 -1 -3  2  4 -1  0 -3 -2  0 -1 -1 -1  0  0 -3 -2 -1    6  18   2   0   0  11  31   3   2   0   2   1   1   4   2   8   4   0   0   4  0.33 inf
  41 Q    0 -1 -2 -1 -3  2 -1 -2 -3 -2 -2 -1 -3 -4  6  1 -1 -4 -3 -2    6   3   0   3   0  14   2   1   0   2   3   1   0   0  43  15   3   0   0   3  0.82 inf
  42 Q    0  0 -1 -2 -1  4  0 -2 -1 -1 -2  0  1  0  1  2  0 -3 -2 -1    7   2   1   1   1  28   4   2   1   3   2   5   5   4   6  18   6   0   0   5  0.25 inf
  43 Q    0  1 -1 -1 -1  3  2  1 -1 -2 -2  0 -2  0 -1  1  0  0 -1 -1    8  10   2   1   1  18  14  10   1   2   2   4   0   6   1   9   4   1   2   5  0.15 inf
  44 Q   -1  5  0 -1 -4  2  2 -2  0 -3 -2  1 -2 -3  2  0 -2 -4 -3 -3    5  38   3   2   0  11  13   2   2   1   3   4   0   1   9   6   1   0   0   0  0.51 inf
  45 F    0 -3 -1 -2 -3 -1 -2 -3  1 -1 -1 -2 -2  4  5 -2 -2 -1  1 -1    8   0   3   1   0   2   2   1   4   2   6   1   0  21  37   1   1   1   5   5  0.68 inf
  46 S    0  0 -1 -1 -1 -1 -2  4  0 -3 -4 -1 -3 -3  1  3  0  0 -3 -2    3   5   1   3   1   1   1  38   2   1   0   2   0   0   7  25   5   1   0   2  0.48 inf
  47 S   -1 -1  1  3  2  1  0  0  0 -3 -3 -1 -3 -4  1  3  0 -4 -2 -3    2   2   5  16   5   6   6   6   3   2   1   1   0   0   6  36   2   0   1   1  0.35 inf
  48 L    1  0 -1 -1 -2  0 -1  0  0  0  1  0  0 -1 -1  0  1 -2 -1  0   14   6   1   3   0   5   2   6   2   2  24   7   0   2   2   3  12   0   2   7  0.05 inf
  49 D   -1 -2 -1  3 -3  0  2 -2 -1 -2 -3 -1 -2 -2  3  1  1 -3 -3 -1    4   1   1  21   0   3  17   2   1   1   2   1   0   2  18  13   8   0   0   5  0.40 inf
  50 D    0  0  0  5 -4  1  3 -1 -2 -3 -3 -1 -3 -4 -2  1 -1 -4 -2 -3    9   4   1  39   0   6  19   4   0   0   2   2   0   0   0   8   1   0   1   1  0.56 inf
  51 K   -1  1 -2 -3 -3  0  0 -1  0 -1 -1  3 -1  4 -1 -1 -2 -2  0  0    3   7   0   0   0   3   4   4   2   1   5  25   1  28   2   4   1   0   2   9  0.27 inf
  52 P    0 -2 -1  0  0  0 -1 -2 -1 -1 -2 -2 -1 -3  5  2 -1  0 -2  1    5   0   2   4   2   5   2   1   1   2   2   1   1   0  29  24   2   2   1  14  0.46 inf
  53 Q   -1  1  2  1 -3  4  0 -1  3 -4 -3  0 -2 -1  0 -1 -2 -2  3 -3    3   7  14  10   0  23   2   3   9   0   2   2   1   2   4   3   0   0  14   0  0.38 inf
  54 F   -3 -4 -5 -5 -4 -4 -3 -3 -4  0  2 -4 -1  7 -5 -4 -3 -2  1  1    1   1   0   0   0   0   1   2   0   3  18   0   0  59   0   0   0   0   1  12  1.08 inf
  55 P   -2 -1 -2  0 -5 -1 -1 -1  2 -4 -3 -1 -2 -4  7 -1 -2 -5 -4 -3    1   3   1   5   0   3   2   6   6   0   3   4   1   0  59   4   1   0   0   1  1.24 inf
  56 G   -1 -3 -1 -2 -4 -3 -3  5 -2  1  0 -1 -2 -2 -4 -1 -2 -4 -3 -1    2   0   2   1   0   0   1  56   1  11  11   5   1   2   0   4   0   0   0   3  0.66 inf
  57 A    3 -1 -2 -2 -2 -2 -2  1  1 -1 -1 -1 -1 -3  3  1 -1 -4 -1 -1   38   3   1   2   0   1   1   9   5   5   6   1   1   0  14  10   2   0   1   1  0.31 inf
  58 S   -1  2  2  0 -3  1  0 -2 -1 -4 -3  3 -2 -4  2  2 -1 -4 -3 -3    3  11  14   5   0   6   5   2   1   0   1  23   1   0   9  18   2   0   0   0  0.38 inf
  59 A    4 -2 -1 -2 -1 -2 -2 -2 -2  0 -2 -2  0 -3 -1  2  1 -4 -3  1   47   1   2   1   1   0   0   0   0   4   2   0   2   1   2  19   7   0   0  11  0.45 inf
  60 E    0  0 -1 -1 -4  2  3  2 -2 -3 -3  1 -2 -4  2  0 -1 -2 -3 -3    5   5   0   1   0   9  26  20   0   1   1  11   0   0  12   4   2   0   0   1  0.41 inf
  61 F    1 -3 -3 -3 -3 -2 -1 -4 -3 -1 -1 -3 -2  6 -2 -1  0  3  2 -1   12   0   1   1   0   1   4   0   0   2   2   1   0  49   2   5   7   3   6   4  0.67 inf
  62 I   -1 -3 -2 -2 -2  0 -3 -3 -3  2 -1 -2 -1 -2 -3  0  4 -4 -3  4    4   0   1   1   0   4   0   0   0  10   1   1   0   1   0   5  36   0   0  34  0.53 inf
  63 D   -1  1  2  3 -3  0  1 -1  2 -3 -3 -1 -3 -3  2  1  1 -4 -1 -3    4  10  11  22   0   2   6   3   7   0   1   1   0   1  10  11   9   0   1   0  0.34 inf
  64 K   -1  3  0  1 -2  2  2 -2 -1 -3 -3  4 -3 -4 -1  0  1 -4 -3 -3    3  16   4   7   1   7  14   1   1   0   0  30   0   0   1   6   8   0   0   0  0.44 inf
  65 L   -2 -4 -4 -5 -3 -3 -4 -5 -4  0  4 -3  5 -2  4 -3 -2 -4 -3  1    3   0   0   0   0   0   0   0   0   3  41   0  20   1  22   0   0   0   0   8  0.82 inf
  66 E   -1  0  0  2 -4  1  3 -2  0 -3 -3  2 -3 -4  1  1  0 -4 -2 -3    4   4   3  15   0   5  27   1   2   1   1  12   0   0   7  11   5   0   1   1  0.38 inf
  67 F   -3 -4 -4 -5 -4 -3 -3 -3 -2  1  0 -3  0  7 -2 -3  1  2  0  1    1   0   0   0   0   1   1   1   0   8   6   1   2  54   3   1   9   3   0   9  0.83 inf
  68 I    0 -1 -2 -1 -2 -1  1 -3 -2  4  1 -2  0  0 -3 -1  0 -3 -2  2    7   3   1   2   0   2  10   1   1  33  13   1   1   3   0   3   5   0   0  13  0.21 inf
  69 Q    1  0  2  2 -3  4  1 -2  1 -3 -1  0 -1 -3  0  0  0 -4 -3 -2   14   3  14  11   0  23   5   1   3   0   5   3   2   0   4   5   6   0   0   1  0.29 inf
  70 P   -1  1 -2  0 -2  0  3  0 -1 -4 -4  0 -4 -5  6 -1 -2 -5 -4 -4    3   7   1   5   1   3  21   6   2   0   0   4   0   0  43   4   1   0   0   0  0.91 inf
  71 N    1 -1  3  2 -2  0  2 -1 -1 -3 -3  0 -1 -3 -2  1  1 -2 -2 -1   13   3  19  12   0   1  14   2   1   1   2   3   1   0   1  12  10   0   1   3  0.27 inf
  72 V    1 -2 -1  2 -2  0  1 -1 -2  0 -1 -1 -1 -2  2  1  0 -3 -2  2   10   0   2  13   0   4   9   2   1   4   3   2   1   1  11  10   6   0   1  21  0.16 inf
  73 I   -1  0 -2  0 -2  0  1 -3 -1  2  0 -1  1  1 -3 -1  0 -2  2  0    4   4   1   6   0   5  13   1   1  20   7   3   6   5   0   3   5   0  12   5  0.11 inf
  74 S    0  1  0  2 -2  0  2 -2  0 -3 -2  0 -2 -4  2  2  1 -4 -3 -3    6   9   4  12   1   2  15   1   2   0   3   5   1   0   9  22   7   0   0   0  0.29 inf
  75 G    1  1 -1  1 -3  1  0  3 -2 -3 -2  0 -2 -3  2  0  0 -3 -2 -2   18   8   1   8   0   9   4  24   0   1   3   4   0   0   9   3   5   0   1   1  0.25 inf
  76 I   -2 -4 -3 -4 -3 -4 -3 -5 -3  5  2 -3  2  4 -4 -3 -1 -1  0  1    1   0   2   1   0   0   2   0   0  45  16   1   4  18   0   0   2   1   2   4  0.62 inf
  77 P   -2 -3 -3 -2 -5 -1  0 -1 -3 -4 -5 -2 -4 -5  8  0 -2 -5 -5 -4    1   1   1   1   0   2   8   5   1   1   0   1   0   0  69   8   1   0   0   0  1.70 inf
  78 I   -2 -3 -3 -4  3 -3 -3 -4 -4  4  2 -3  3 -1 -3 -2  3 -4 -3  2    0   0   0   0   8   1   0   0   0  28  16   1  11   1   1   0  22   0   0  11  0.51 inf
  79 Y   -3 -3 -5 -5 -4 -4 -4 -5 -1  2  0 -4 -1  4 -5 -4 -3  0  7  2    0   1   0   0   0   0   0   0   0  11   7   1   0  17   0   0   0   0  45  17  1.08 inf
  80 R   -3  7 -2 -4 -6  4 -2 -4  1 -6 -5  1 -4 -5 -4 -2 -2 -5 -4 -5    1  69   0   0   0  20   0   0   3   0   0   3   0   0   0   2   1   0   0   0  1.53 inf
  81 V   -2 -4 -5 -5 -2 -4 -5 -5 -5  4  0 -4 -1 -2 -5 -4 -1 -5 -2  6    1   1   0   0   1   0   0   0   0  21   7   0   0   0   0   0   3   0   1  66  1.09 inf
  82 M   -3 -4 -5 -6 -2 -4 -5 -6 -5  1  5 -4  6 -2 -5 -4 -2 -4 -3  0    0   0   0   0   1   0   0   0   0   6  61   0  28   0   0   0   1   0   0   3  1.22 inf
  83 D   -3 -2  4  7 -5  0 -1 -1 -3 -5 -6 -1 -5 -6 -4  0 -2 -6 -5 -5    2   1  19  64   0   3   1   3   0   0   0   3   0   0   0   5   1   0   0   0  1.34 inf
  84 R    0  3  0  2 -4  1  3 -2  0 -3 -2  1 -2 -3  0  0 -1 -4 -2 -3    6  17   2  14   0   6  24   2   1   0   4   6   1   1   5   7   3   0   1   0  0.33 inf
  85 Q   -1 -2  2  5 -3  3  3 -2  1 -4 -4  0 -3 -4 -3 -1 -1 -4 -2 -3    4   1  10  35   0  15  19   1   3   1   1   3   0   0   0   2   2   0   1   1  0.65 inf
  86 G   -2 -4 -2 -3 -5 -4 -4  7 -2 -6 -6 -4 -5 -5 -4 -2 -4 -5 -5 -5    1   0   1   1   0   0   0  92   1   0   0   0   0   0   0   2   0   0   0   0  1.94 inf
  87 Q   -1  1  2  0 -2  3  2 -2  0 -2 -3  1 -1 -3 -2  0  1 -4 -2 -1    3   9  13   4   1  19  15   0   2   1   1   8   1   0   0   6  10   0   1   5  0.31 inf
  88 I    2 -3 -4 -3 -2 -3 -3 -3 -3  4  2 -3  0 -1 -1 -2 -1  0 -2  3   19   0   0   1   0   1   1   1   0  29  20   1   1   1   2   0   2   1   0  19  0.39 inf
  89 I   -1 -2 -2 -3 -2 -2 -2 -4  1  3  1 -3 -1 -1 -3 -2 -1 -3  0  4    2   1   1   1   0   2   1   0   4  21  12   1   0   1   0   2   2   0   4  44  0.47 inf
  90 N   -1 -2  4  3 -2 -1  1  3 -2 -4 -4  0 -3 -4  0  0 -1 -4 -3 -3    3   1  26  21   1   1   9  21   0   1   1   4   0   0   5   5   1   0   0   1  0.52 inf
  91 P   -2 -2  0  2 -3 -1  2  2 -3 -4 -4  1 -3 -4  5 -1 -2 -4 -4 -4    2   0   4  11   0   2  16  14   0   0   1   8   0   0  36   4   2   0   0   0  0.74 inf
  92 S    2 -2 -1  0 -3  0  2 -1  0 -3 -3 -1 -2 -2 -1  2  0  7 -2 -2   17   1   2   6   0   2  14   3   2   1   2   3   0   1   3  22   3  16   0   1  0.43 inf
  93 E    1  0  0  0 -1  2  3 -1  1 -2 -1  0 -1 -1  0  0  0 -2  0 -1   15   4   2   4   2   9  22   2   3   1   4   5   1   3   3   5   6   0   4   5  0.14 inf
  94 D    0 -1  0  4 -2 -1  1  0 -1 -1  0 -1  2 -1 -2 -1 -1 -3 -2  0    7   1   4  31   1   1   7   6   2   2   7   4   8   3   0   2   2   0   1  11  0.21 inf
  95 P   -1 -3 -3 -2 -4 -2  0 -3 -2 -2 -2 -2 -3 -4  7 -1 -2 -4 -3 -2    3   1   0   2   0   2   5   1   1   2   4   1   0   0  69   3   1   0   1   3  1.59 inf
  96 H   -1  0  1  3 -2  3  2 -1  2 -3 -3  1 -2 -2  0 -1  0 -3 -2 -2    4   2   7  23   1  15  11   3   6   1   1  11   0   2   3   2   4   0   0   3  0.32 inf
  97 L   -2 -3 -4 -4 -3 -3 -3 -4 -4  3  4 -4  2  1 -4 -3 -2 -3 -1  1    1   0   0   0   0   0   1   1   0  18  55   0   3   7   0   0   1   0   1   9  0.65 inf
  98 P   -1 -3  0  3 -3 -2  0 -1 -2 -4 -4 -1 -3 -4  4  3  2 -4 -4 -3    3   0   2  20   0   0   5   3   0   0   1   2   0   0  21  30  12   0   0   0  0.61 inf
  99 K   -1  2  0  4 -4  1  2 -2 -2 -3 -3  3 -3 -4  2 -1 -2 -4 -3 -2    3  14   3  25   0   7  12   1   0   0   1  19   0   0  10   1   1   0   0   3  0.46 inf
 100 E    0 -2 -1  3 -5  1  6 -2 -1 -4 -4 -1 -4 -5 -3 -1 -2 -5 -4 -3    8   0   2  19   0   3  59   2   1   0   0   2   0   0   1   1   1   0   0   1  0.97 inf
 101 K   -1  0 -1 -1 -3  3  2 -3  0 -1  1  1  0 -1 -2 -1  1 -1 -2  0    4   3   1   1   0  19  19   1   2   2  14   7   2   3   0   2  14   1   1   6  0.20 inf
 102 V    2 -3 -4 -4  0 -3 -3 -3 -4  1  3 -3  1 -1 -3 -2 -1 -3 -2  3   20   0   0   0   2   0   0   1   0   4  43   0   2   1   0   0   2   0   1  23  0.47 inf
 103 L   -2  2 -2 -3 -3 -1 -1 -3 -2  2  3  0  1 -2 -3 -2 -1 -3 -2  2    0  12   1   0   0   3   2   1   1  10  37   8   2   0   0   0   2   0   0  19  0.31 inf
 104 K    0  3  0  0 -4  1  2 -2 -1 -4 -3  4 -3 -4 -2 -1  0 -2 -3 -3    8  13   3   4   0   5  18   1   1   0   1  37   0   0   0   2   4   0   0   1  0.51 inf
 105 L   -1 -3 -4 -4 -3 -3 -4  1 -2  2  2 -3  6  2 -4 -2 -2  2 -1  0    3   0   0   0   0   0   0  15   1  11  19   0  32  10   0   1   0   3   1   2  0.56 inf
 106 Y   -4 -4 -4 -5 -4 -3 -4 -4  1 -2  1 -4  4  1 -5 -4 -4 -1  8 -3    0   0   0   0   0   1   0   1   2   0  14   0  11   3   0   0   0   0  65   0  1.50 inf
 107 K   -2  6 -1  0 -4  1  1 -3  0 -4 -3  3 -3 -4 -3 -1 -1 -4 -3 -4    1  47   1   5   0   5   8   1   2   0   2  19   0   0   0   4   3   0   0   0  0.74 inf
 108 S    1  1  1  2 -2  1  0 -2  2 -2 -2  1 -2 -2 -2  1  1  1 -1 -2   12   8   9  12   1   5   3   1   8   2   3   7   0   1   0  13  12   2   2   1  0.17 inf
 109 M   -4 -4 -5 -6 -1 -3 -5 -5 -4 -1  0 -4 10 -2 -5 -4 -3 -4 -4 -2    0   0   0   0   2   0   0   0   0   1   4   0  90   1   0   0   0   0   0   0  2.44 inf
 110 T   -1 -1 -3 -3 -1 -1 -2 -3 -3  2  2 -1  2 -2 -3 -2  2 -2 -2  3    4   4   1   0   1   2   1   0   0   9  23   3   6   0   0   1  15   0   0  29  0.29 inf
 111 L   -1  2 -2 -3 -1  1 -1 -3 -2 -1  3  1  0  1 -3 -1  1  2  1 -1    3  12   0   0   1   6   2   1   0   0  35   8   1   7   0   2  13   3   6   1  0.21 inf
 112 L    0 -3 -2 -3 -2 -2 -3 -2 -2  1  3 -3  2 -1 -3 -1  3 -3 -2  1    9   0   1   0   0   1   0   2   1   7  35   0   5   2   0   2  23   0   0  10  0.32 inf
 113 N   -3  6  4 -2 -4  1 -1 -3 -1 -5 -4  0 -3 -4 -1  1 -2 -5 -3 -4    0  49  25   0   0   5   2   0   1   0   0   1   0   0   4  11   0   0   0   0  0.91 inf
 114 T    1 -2 -2 -3 -2 -1 -1 -3  1  3  0 -2  0 -2 -3  0  3 -3 -2  2   13   1   0   0   0   2   2   0   5  24   5   1   2   0   0   6  25   0   1  13  0.28 inf
 115 M   -2 -3 -3 -5 -3 -3 -4 -4 -3  0  2 -4  7  4 -4 -3 -3  3  1  1    2   0   1   0   0   0   0   0   0   3  18   0  36  22   0   0   0   4   5   7  0.82 inf
 116 D   -4 -4 -1  8 -6 -3 -1 -4 -4 -5 -6 -3 -5 -6 -4 -3 -3 -6 -5 -5    0   0   0  96   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  2.21 inf
 117 R    0  3  1  0 -3  2  2 -2 -1 -2 -2  1 -1 -3 -2  0  0 -3 -3 -1    9  21   7   5   0  11  19   2   0   1   4   6   1   0   0   3   6   0   0   4  0.27 inf
 118 I   -3  5 -3 -4 -4 -2 -3 -4 -3  5 -1  0 -1 -2 -4 -3 -2 -4 -3  0    0  42   0   0   0   0   0   0   0  41   3   5   1   0   0   0   1   0   0   4  0.83 inf
 119 L    1 -3 -4 -4  1 -3 -4 -4 -3 -1  3 -3  7  2 -4  0 -2 -2 -1 -1   11   0   0   0   3   0   0   0   0   0  30   0  38   8   0   6   0   0   1   0  0.72 inf
 120 Y   -3 -3 -3 -4 -3 -2 -4 -4  0  2  1 -3  1  3 -4 -3 -1 -1  6  1    0   0   1   0   0   2   0   0   1  12  16   0   4  11   0   1   3   0  37  11  0.68 inf
 121 E    0  1  2  1 -3  0  3 -1 -1 -2 -2  0  0 -3 -2  1  0 -4 -3 -2    6   7  11   8   0   2  31   4   0   3   2   2   4   0   0  15   3   0   0   1  0.31 inf
 122 S    3 -3 -2 -3 -2 -2 -2 -2 -3  0  2 -2  0 -2 -3  3 -1 -3 -1  0   36   0   0   0   0   0   0   1   0   4  26   0   2   0   0  24   0   0   1   3  0.41 inf
 123 Q   -3 -1  1 -3 -5  8 -1 -4  1 -3 -4 -1 -3 -5 -4 -2 -3 -4 -4 -4    0   0   8   0   0  84   0   0   3   1   0   0   0   0   0   1   0   0   0   0  1.83 inf
 124 R   -4  8 -3 -4 -6 -2 -3 -5 -3 -6 -5  0 -4 -6 -5 -4 -4 -6 -5 -5    0 100   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  2.34 inf
 125 Q   -4 -2 -3 -3 -6  9 -1 -5 -1 -5 -5 -1 -3 -6 -4 -3 -3 -5 -4 -5    0   0   0   0   0  97   0   0   1   1   0   0   0   0   0   0   1   0   0   0  2.33 inf
 126 G   -2 -4 -3 -4 -5  0 -4  7 -4 -6 -6 -1 -5 -6 -4 -3 -4 -5 -5 -5    0   0   0   0   0   4   0  88   0   0   0   4   0   0   0   0   0   0   0   0  1.76 inf
 127 R   -3  7 -3 -1 -5  0 -2 -4 -3 -2 -4  3 -3 -5 -4 -3 -3 -5 -4 -3    0  69   0   4   0   3   0   0   0   4   1  18   0   0   0   0   0   0   0   1  1.35 inf
 128 I   -3 -4 -4 -5 -3 -4 -4 -5  1  5  2 -4  3 -1 -4 -3  1 -4 -3  2    0   0   0   0   0   0   0   0   4  49  19   0   9   1   0   0  11   0   0   7  0.72 inf
 129 S   -1 -3 -2 -3 -3 -2 -3  3 -3 -4 -3 -3 -3 -4 -3  6 -1 -5 -4 -1    1   0   0   0   0   0   0  23   0   0   2   0   0   0   0  67   1   0   0   4  0.99 inf
 130 F   -4 -5 -5 -5 -4 -5 -5 -5 -4 -3 -2 -5 -2  8 -1 -4  2 -2  0 -3    0   0   0   0   0   0   0   0   0   0   0   0   0  80   4   0  13   0   0   0  1.77 inf
 131 Y   -3 -4 -4 -5 -5 -4 -4 -5 -1  0 -3 -4 -2  1 -5 -1 -4 -1  9 -3    2   0   0   0   0   0   0   0   0   5   0   0   0   2   0   4   0   0  84   0  2.12 inf
 132 M    2 -3 -4 -4 -3 -3 -4 -3 -4  0  1 -3  8 -2  0 -1 -2 -4 -3  0   17   0   0   0   0   0   0   2   0   5   8   0  55   0   4   4   0   0   0   4  1.00 inf
 133 T   -1 -2 -2 -3 -3  2 -2  0 -3 -3 -3  0 -3 -4  5 -1  4 -4 -3  0    2   0   0   0   0  14   0   6   0   0   1   7   0   0  27   2  32   0   0   8  0.67 inf
 134 N    1 -1  3 -2  4 -2 -2 -2  2 -3 -1 -2  0  0 -3  3  1 -3 -1 -2    9   4  17   0  13   0   0   1   7   0   5   0   3   5   0  26   7   0   1   1  0.33 inf
 135 Y    2  0 -2 -2 -2  0  0 -2  0 -1  0 -1  0  1 -2  0  1 -2  3 -1   20   5   1   2   0   4   6   1   1   3  11   2   1   6   0   7  13   0  17   1  0.16 inf
 136 G   -1 -4 -3 -4 -5 -4 -4  7 -4 -6 -6 -4 -5 -5 -4 -2 -4 -5 -5 -5    4   0   0   0   0   0   0  93   0   0   0   0   0   0   0   0   0   0   0   0  1.93 inf
 137 E   -3  0 -2 -1 -5  4  6 -1 -1 -5 -5 -1 -4 -5 -3 -2 -3 -5 -4 -4    0   4   0   0   0  22  66   4   1   0   0   0   0   0   0   0   0   0   0   0  1.28 inf
 138 E   -3 -3 -3 -1 -6  0  7 -1 -3 -5 -5 -2 -4 -5  0 -3 -3 -5 -4 -5    0   0   0   0   0   1  88   4   0   0   0   0   0   0   4   0   1   0   0   0  1.66 inf
 139 G    5 -4 -3 -4 -1 -3 -3  4 -4 -4 -4 -3 -3 -4 -3 -1 -2 -4 -4 -3   67   0   0   0   1   0   0  29   0   0   0   0   0   0   0   0   0   0   0   0  1.10 inf
 140 T    2 -1 -2 -3  2 -2 -2 -3 -3  2 -1 -2  1 -2 -3  1  3 -4 -3  1   18   4   1   0   4   0   0   0   0  19   4   0   5   0   0  14  21   0   0   8  0.27 inf
 141 H    0 -2  0  0  1  4 -1  0  4 -1 -1 -1 -1 -3 -2  1 -1  3 -2  0    9   0   4   4   3  26   0   5  13   3   4   0   2   0   1  10   2   4   0   8  0.25 inf
 142 V   -1 -4 -4 -4  2 -4 -4 -2 -4  4  1 -4  0  0 -4 -2 -1 -4 -2  4    2   0   0   0   5   0   0   4   0  26  11   0   1   3   0   1   3   0   0  43  0.58 inf
 143 G    3 -1 -3 -3 -1 -3 -3  6 -4 -4 -4 -3 -4 -5 -3 -1 -3 -4 -4 -4   30   4   0   0   1   0   0  62   0   0   0   0   0   0   0   1   0   0   0   0  1.16 inf
 144 S    0 -3 -2 -2 -1  0 -2  1  0 -2 -3 -2 -2  0 -3  5  1 -4 -3 -2    6   0   0   0   1   5   0   9   3   2   1   0   0   5   0  60   6   0   0   2  0.63 inf
 145 A    5  0 -3 -3 -2  0 -2  0  1 -2 -1 -2 -1 -3 -3  1 -1 -4 -3 -1   61   6   0   0   0   4   0   5   4   0   4   0   1   1   0   6   3   0   0   3  0.58 inf
 146 A    4 -1 -2 -3 -2 -2 -2  1  1 -2  0 -1  2  1 -2  0 -2 -3  0 -2   44   2   0   0   0   0   0   8   4   1  10   4   6   9   0   7   0   0   4   0  0.31 inf
 147 A    6 -1 -4 -4 -3 -2 -3  0 -4 -1 -3 -3 -2 -4 -2 -1 -2 -5 -4 -1   80   4   0   0   0   1   0   5   0   4   1   0   1   0   1   0   0   0   0   3  1.04 inf
 148 L   -3 -4 -2 -5 -3 -4 -1 -5 -4  0  6 -4  2 -2 -5 -4 -2 -1 -3  0    0   0   3   0   0   0   4   0   0   2  82   0   3   0   0   0   1   1   0   4  1.04 inf
 149 D    0  1  1  3 -3  0  2  0  0 -4 -3  0 -3 -4  1  1  0 -4 -3 -3    9   6   5  22   0   2  19   6   2   0   1   6   0   0   7   9   6   0   0   0  0.34 inf
 150 N    0  0  1  1 -3  0  0  0 -2 -2 -2  2  0 -3  4  1 -1 -4 -3 -2    5   4   6   9   0   4   5   5   0   2   3  15   3   0  22  14   1   0   0   1  0.35 inf
 151 T   -1  1  0  3 -4  1  2  2  0 -3 -4  0 -3 -4 -3  0  1 -4 -3 -2    2   8   4  21   0   7  17  17   2   0   0   3   0   0   0   4  11   0   0   4  0.35 inf
 152 D   -4 -4 -1  8 -6 -3 -1 -4 -4 -5 -6 -3 -5 -5 -4 -3 -4  3 -5 -5    0   0   0  92   0   0   0   0   0   0   0   0   0   0   0   0   0   4   0   0  2.11 inf
 153 L   -3 -3 -4 -4 -3 -2 -1 -4  0  0  1 -3  5  1 -2 -3 -2  8  0  2    1   0   0   0   0   0   5   0   3   3  14   0  23   7   2   0   2  21   1  17  0.72 inf
 154 V   -1 -3  0 -3  3 -3 -3 -3 -3  4  1 -3  2 -2 -3 -1 -1 -3 -2  3    2   0   5   0   7   0   0   1   0  29  11   0   6   1   0   5   1   0   0  31  0.44 inf
 155 F   -3 -4 -4 -5 -4 -4 -4 -4 -3 -2  1 -4  2  7  0 -4 -3  0  3 -1    1   0   0   0   0   0   0   0   0   0  12   0   5  59   4   0   1   1  10   3  1.12 inf
 156 G    3 -4 -4 -4  3 -3 -3  1 -4 -4 -3 -3 -3 -5  6 -1 -2 -5 -4 -3   27   0   0   0   6   0   0  12   0   0   2   0   0   0  49   2   1   0   0   0  1.22 inf
 157 Q   -1  0 -2 -3  0  6 -1  0  3 -4 -4 -1 -3 -4 -3  1  2 -4 -2 -4    2   4   0   0   2  48   0   8   7   0   0   0   0   0   0  12  16   0   1   0  0.77 inf
 158 Y   -4 -4 -5 -6 -5 -4 -5 -6 -1 -4  0 -5 -3  1 -1 -4 -4 -1  9 -4    0   0   0   0   0   0   0   0   0   0   9   0   0   1   4   0   0   0  85   0  2.20 inf
 159 R   -4  8 -3 -4 -6 -2 -3 -5 -3 -6 -5 -1 -4 -5  2 -3 -4 -5 -4 -5    0  88   0   0   0   0   0   0   0   0   0   0   0   0  11   0   0   0   0   0  1.94 inf
 160 E   -3 -2 -2  3 -5  3  6 -1 -2 -5 -5 -1 -2 -5 -3 -1 -3 -5 -4 -3    0   0   0  15   0  13  61   4   0   0   0   2   1   0   0   3   0   0   0   2  1.07 inf
 161 A    1 -2 -1 -2 -3  3 -1 -1  4 -1  0 -2 -1 -2  1  0  0 -3  1  0   18   0   1   0   0  20   2   4  15   2   8   0   1   0   7   4   5   0   4   9  0.25 inf
 162 G    1 -4 -2 -3 -4 -3 -4  6 -4 -5 -5 -2 -4 -5  1  0 -2 -5 -5 -4   12   0   0   0   0   0   0  71   0   0   1   2   0   0   7   5   1   0   0   1  1.24 inf
 163 V    2 -3 -4 -4 -2  1 -3 -3 -4  2  1 -3  0 -2 -3 -2 -1  1 -3  4   22   0   0   0   0   7   0   1   0   8  10   0   1   1   0   1   1   2   0  46  0.49 inf
 164 L   -1 -4 -4 -5  0 -3 -4 -3 -4  1  5 -3  2  2 -4 -3 -2  0 -1 -1    6   0   0   0   2   0   0   2   0   5  65   1   5   7   0   1   2   1   1   1  0.68 inf
 165 M   -2 -2 -4 -4 -3  0 -3 -4 -1  2  3 -2  5  0 -4 -3 -1 -2 -1  1    3   2   0   0   0   4   0   0   2  15  34   2  25   4   0   0   2   0   1   6  0.53 inf
 166 Y    1 -3 -3 -4 -2  0 -2 -4  1 -2 -1 -3 -1  0 -4 -2 -1  8  5  0   14   0   1   0   1   6   2   0   4   0   4   0   1   2   0   2   5  27  25   7  0.93 inf
 167 R   -3  7 -2 -2 -5  0 -2 -4  4 -5 -3  1 -2  0 -4 -2 -3 -5 -3 -5    1  71   0   2   0   2   0   1  11   0   2   4   1   4   0   1   0   0   0   0  1.35 inf
 168 D   -2 -4 -2  3 -5 -2 -2  6 -4 -6 -6 -3 -5 -5 -4 -1 -4 -5 -5 -5    0   0   1  15   0   1   1  78   0   0   0   0   0   0   0   2   0   0   0   0  1.54 inf
 169 Y   -3 -2 -4 -5 -1 -2 -4 -5  0 -1  1 -4  2  5 -5 -4 -3  3  6  0    1   2   0   0   1   2   0   0   2   2  13   0   6  33   0   0   0   3  30   5  0.88 inf
 170 P   -2 -2 -2 -1 -4 -2 -2 -2 -2 -3 -4 -2 -4 -5  6  2  4 -5 -4 -3    1   1   0   2   0   0   1   2   1   0   0   2   0   0  41  15  33   0   0   0  1.09 inf
 171 L   -2 -4 -5 -5 -3 -4 -4 -5 -4  2  5 -4  3 -1 -3 -3 -1 -2  0  1    1   0   0   0   0   0   1   0   0   8  69   0   6   1   1   0   4   0   3   5  0.83 inf
 172 E   -1 -1 -1  4 -3  1  2 -3 -1 -1 -1  1 -2 -2 -1 -1  0 -3 -1  0    3   2   1  27   0   7  17   0   1   3   4   9   0   1   2   3   4   0   3  11  0.27 inf
 173 L   -1  0  1  3 -4  4  2 -3 -1 -3  0  0 -1 -4 -2 -1  0 -4 -2 -3    2   4   8  19   0  25  15   0   1   0  12   3   2   0   1   3   4   0   0   0  0.40 inf
 174 F    0 -4 -4 -4 -2 -3 -3 -4 -3  1  1 -3  4  5 -4 -2  1 -2  1  0   10   0   0   0   0   0   1   0   0   8   9   0  13  38   0   0  11   0   3   6  0.57 inf
 175 M   -1 -4 -4 -5 -1 -3 -4 -5 -4  1  2 -4  7  3 -4 -3 -2 -3 -1  1    6   0   0   0   1   0   0   0   0   8  16   0  45  13   0   0   2   0   1   7  0.90 inf
 176 A    0 -2  4  1  3  0 -1 -1  0 -2  1 -2 -2 -3 -2  1 -1 -4 -3 -2   11   1  30   8   8   5   1   3   2   0  19   0   0   0   1  11   0   0   0   0  0.33 inf
 177 Q   -3 -1 -2 -2 -5  7 -1 -3  1 -5 -4 -2 -3  1 -4 -3 -3  2  3 -4    0   2   1   1   0  69   1   1   2   0   0   0   0   6   0   1   0   2  13   0  1.38 inf
 178 C   -2 -4 -3 -5  8 -4 -4 -4 -4  2  2 -4  1 -2 -4  0 -2  6 -2 -1    2   0   1   0  37   0   0   0   0  11  21   0   5   1   0   8   1  11   1   2  0.99 inf
 179 Y   -3  1 -2 -5 -2 -3 -4 -4 -2 -1  0 -2  4  6 -5 -3 -3 -1  5 -2    1   8   3   0   1   0   0   1   0   2   6   1  12  37   0   1   0   0  26   0  0.89 inf
 180 G    2 -3 -2 -3 -2 -1 -3  5 -3 -5 -5 -3 -4 -4 -3  3 -2 -4 -2 -4   15   0   0   0   1   2   0  55   0   0   0   0   0   0   0  24   1   0   2   0  0.96 inf
 181 N   -3  0  7  0 -5 -2 -1 -3  4 -5 -5 -2 -4 -5 -2 -1  1 -5 -3 -4    1   5  65   2   0   0   2   0  12   0   0   0   0   0   1   2   9   0   0   0  1.28 inf
 182 I    1  0 -1 -1  0  0  2 -2  2 -1 -2  1 -1  0 -2  0 -1 -3 -1  0   16   5   2   1   3   2  22   1   7   3   0  12   1   6   1   6   2   0   1   9  0.15 inf
 183 S    0  1  1  1 -1  0  1  1  0 -2  0  1 -1 -1 -2  1 -1 -2 -1 -1    7   6   5   9   1   3  13   9   3   1  12   7   1   2   1  13   1   0   3   2  0.08 inf
 184 D   -2 -1  0  7 -1 -2  0 -1 -2 -3 -3 -2 -3 -3 -2 -1 -2 -3 -3 -3    2   3   2  72   1   1   2   3   0   1   3   1   0   1   1   2   1   0   1   1  1.17 inf
 185 L   -1 -1  0 -1 -1  0  0 -2  0 -1  1  0 -1 -1  5 -1 -1 -2  0 -1    3   3   4   3   1   5   7   3   2   3  15   5   1   1  30   3   3   0   5   2  0.35 inf
 186 G    0 -2 -1 -2  0 -2 -2  5 -2 -1  1 -2  0 -2 -2 -1 -2 -1 -3 -2    5   2   3   2   2   1   1  50   0   3  18   1   3   1   1   3   1   1   1   2  0.50 inf
 187 K   -2  3 -2 -2 -4  1 -1 -2  1 -4 -3  6 -2 -4 -2 -1 -2 -4 -3 -3    1  13   1   1   0   3   1   2   3   1   3  65   1   0   1   2   1   0   0   1  0.93 inf
 188 G   -2 -5 -3 -4 -5 -4 -5  7 -5 -3 -6 -4 -5 -5 -5 -3 -4 -5 -5 -5    1   0   0   0   0   0   0  96   0   2   0   0   0   0   0   0   0   0   0   0  2.06 inf
 189 R   -3  7  2 -3  0 -1 -2 -2 -2 -4 -4  1 -3 -5 -2 -1 -3 -5 -4 -4    1  72   9   0   2   0   0   3   0   1   0   4   0   0   1   5   1   0   0   0  1.29 inf
 190 Q   -3  0  2 -2 -5  8  0 -4 -1 -5 -4 -1 -2 -2 -4 -2 -3 -4 -2 -2    1   4  10   1   0  74   1   0   1   0   0   1   1   2   0   1   0   0   1   2  1.43 inf
 191 M   -3 -4 -5 -5 -4 -3 -4 -5 -4  1  2 -4  9 -1 -1 -3 -3 -4  0 -1    1   0   0   0   0   0   0   0   0   5  15   0  67   2   4   1   1   0   3   1  1.51 inf
 192 P   -4 -5 -5 -3 -1 -4 -2 -4 -5 -5 -5 -4 -1 -6  8 -4 -4 -6 -6 -5    0   0   0   1   1   0   2   1   0   0   0   0   2   0  92   0   0   0   0   0  2.68 inf
 193 V   -1 -3 -2 -1  0 -2  1 -2 -3  4 -1 -3  0 -2 -3 -2 -1 -4 -3  4    2   0   1   4   2   0  10   3   0  28   1   0   2   0   0   2   3   0   0  40  0.44 inf
 194 H   -3 -2 -1 -3  1 -2 -2  1  9 -3 -2 -3  3 -2 -4 -2 -3 -4 -1 -3    1   1   2   1   3   0   1  11  59   1   4   1  11   1   1   3   1   0   0   1  1.35 inf
 195 Y   -3 -3 -3 -3 -3 -2 -2 -3  1 -2 -2 -2 -1  2 -2 -3 -3  0  8 -2    1   1   1   1   0   2   3   1   2   2   3   2   1   5   2   1   1   0  68   3  1.37 inf
 196 G    0 -2 -1 -2 -1 -2 -2  5 -2 -3 -3 -2 -2 -2 -1  2  0 -3 -3 -3    3   1   1   1   1   1   1  56   0   2   2   1   1   2   2  19   5   0   1   1  0.76 inf
 197 C    1 -2 -1 -1  4 -1 -1 -1 -2 -2 -2 -1 -2 -2 -1  4  0  2 -1 -2    8   1   1   2  12   1   3   3   0   1   2   4   1   1   3  48   2   3   2   2  0.45 inf
 198 K   -1  3  0 -2 -4  0  1 -2 -1 -3 -2  5 -2 -4  0 -1 -1 -3 -3 -3    5  18   5   1   0   3  10   1   1   1   2  43   0   0   4   2   2   0   0   1  0.55 inf
 199 E    0  0  0  4 -4  0  3 -1 -1 -3 -3  1 -3 -3 -1 -1 -2 -3 -2 -3    8   5   3  27   0   2  28   4   1   1   2  11   0   0   3   1   1   0   2   1  0.45 inf
 200 R   -1  0 -3 -4 -2 -2 -3 -1  3  0  3 -1  0 -1 -2 -2 -1 -3  1  1    5   5   0   0   1   1   0   4  12   1  43   3   0   1   1   2   2   0   4  14  0.28 inf
 201 H   -3  0  6 -1 -5 -1 -2  1  6 -5 -5  0 -4 -5 -4 -1 -3 -5 -2 -5    1   4  52   1   0   1   0  13  22   0   0   5   0   0   0   3   0   0   0   0  1.14 inf
 202 F   -1 -4 -4 -5 -3 -2 -4 -5 -2  3  0 -4  1  6 -5 -3 -2 -1  3  1    5   0   0   0   0   1   0   0   1  18   3   0   3  46   0   0   2   0  11   9  0.85 inf
 203 V   -2 -3 -3 -4 -3  0 -3 -2  4  0  0 -2  2  5 -4 -3 -2 -2  1  3    1   0   0   0   0   6   0   2  15   2   8   1   7  27   0   0   1   0   3  26  0.51 inf
 204 T   -1 -3 -2 -3 -3 -3 -3 -3 -3 -3 -4 -3  0 -4  3  3  6 -5 -1 -2    3   0   0   0   0   0   0   0   0   0   0   0   2   0  14  22  56   0   2   0  0.97 inf
 205 I   -2 -5 -5 -5 -3 -4 -5 -5 -5  6  0 -4  0 -2  2 -4 -2  0 -3  3    2   0   0   0   0   0   0   0   0  63   3   0   1   0  13   0   1   1   0  16  1.03 inf
 206 S    1 -3 -2 -3  0  2 -2 -2 -3 -5 -5 -2 -4 -5 -3  6  0 -5 -4 -4   10   0   0   0   2   9   0   1   0   0   0   0   0   0   0  75   3   0   0   0  1.15 inf
 207 S    0 -3 -2 -3 -3 -3 -3  2 -3  1 -3 -3 -3 -4 -2  5  0 -5 -4  1    3   0   0   0   0   0   0  15   0  12   0   0   0   0   1  56   3   0   0  10  0.66 inf
 208 P   -3 -4  3 -3 -1 -3 -3 -4 -4  1 -3 -3 -2 -5  7 -3  1 -6 -5 -3    0   0  15   0   1   0   0   0   0   9   2   0   1   0  63   0   9   0   0   0  1.56 inf
 209 L   -3 -4 -5 -3 -3 -4 -5 -6 -5  4  5 -5  0 -2 -5 -4 -3 -4 -3  0    0   0   0   2   0   0   0   0   0  29  67   0   0   0   0   0   0   0   0   2  1.08 inf
 210 A    5 -4 -1 -3 -3 -3 -3  3 -4 -4 -3 -3 -3 -4 -3  0  0 -5 -4 -3   63   0   2   0   0   0   0  27   0   0   1   0   0   0   0   2   5   0   0   0  0.96 inf
 211 T    1 -4 -3 -4 -3 -3 -3 -4 -4 -3 -4 -3 -3 -5 -3  1  7 -5 -4 -2    9   0   0   0   0   0   0   0   0   0   0   0   0   0   1   9  81   0   0   1  1.44 inf
 212 Q   -4  0 -2 -1 -6  8 -1 -5  0 -6 -5 -1 -3 -6 -4 -3 -2 -5 -4 -5    0   2   1   2   0  90   0   0   2   0   0   2   0   0   0   0   1   0   0   0  2.07 inf
 213 I   -3 -4 -5 -5 -3 -4 -4 -5 -3  5  3 -4  3  2 -4 -4 -2 -3  2  1    0   0   0   0   0   0   0   0   0  41  24   0  10   6   0   0   2   0  10   6  0.72 inf
 214 P   -3 -4 -3 -4 -4 -4 -4 -3 -4  0 -2 -3 -3 -5  8 -1 -2 -5 -5  0    0   0   1   0   0   0   0   2   0   7   4   0   0   0  71   4   2   0   0   8  1.71 inf
 215 Q   -3 -2 -2 -3 -5  7 -1 -4  7 -5 -5 -2 -3 -5 -3 -3 -3 -5 -3 -4    1   0   1   0   0  64   0   0  31   0   0   0   0   0   1   0   0   0   0   1  1.79 inf
 216 A    6 -3 -3  0 -3 -2 -1 -1 -3 -3 -3 -3 -3 -4 -3  0  0 -4 -4 -2   79   0   0   5   0   0   3   2   0   0   0   0   0   0   0   2   5   0   0   1  1.02 inf
 217 V    3 -3 -3 -3 -2 -3 -3 -3 -4  1 -2 -3 -1 -3 -3  1  1 -4 -3  4   29   0   0   0   0   0   0   0   0   5   0   0   1   0   0  12  10   0   0  42  0.54 inf
 218 G   -2 -5 -3 -4 -5 -4 -5  7 -4 -6 -6 -4 -5  1 -5 -1 -4 -5 -4 -5    0   0   0   0   0   0   0  90   0   0   0   0   0   6   0   3   0   0   0   0  1.87 inf
 219 A    4 -3 -3 -4  1 -3 -3  0 -3 -2 -2 -3 -2  0 -3  0 -1  6  1  1   42   0   0   0   3   0   0   6   0   1   1   0   0   5   0   8   3  14   5  12  0.55 inf
 220 A    6 -4 -3 -4 -3 -1 -3  2 -4 -3 -4 -3 -3 -4  0 -1 -2 -5 -4 -1   75   0   0   0   0   2   0  14   0   0   0   0   0   0   3   1   0   0   0   4  1.03 inf
 221 Y   -4 -4 -5 -6 -2 -4 -5 -5 -2 -2  0 -4  5  1  0 -4 -4  7  7 -3    0   0   0   0   1   0   0   0   0   1  10   0  17   2   4   0   0  14  50   0  1.45 inf
 222 A    6 -3 -3 -4 -3 -2 -3  2 -4 -4 -4  0 -2 -4 -3  1 -2 -5 -4 -2   74   1   0   0   0   0   0  12   0   0   0   5   1   0   0   7   0   0   0   1  1.01 inf
 223 A    1 -2 -2 -2  0  0  0 -2 -2  0  2 -2  1  2  0  1 -1 -1  0  0   12   0   1   0   2   5   6   1   0   3  25   0   5  10   3  19   1   0   2   5  0.14 inf
 224 K    1  2 -2 -2 -4  0 -1 -3 -3 -4 -4  6 -2 -4  1 -2 -2 -4 -4 -4   15  11   1   1   0   1   1   0   0   0   0  60   1   0   7   0   1   0   0   0  0.89 inf
 225 R   -2  2 -3 -4 -3 -2 -3 -4 -3  3  3  0  3 -1 -4 -3 -2 -1  1  0    1  17   0   0   0   1   0   0   0  18  35   6  12   1   0   0   1   1   5   2  0.41 inf
 226 A    1  3 -1  1 -3  3  0 -2 -2 -4 -3  3 -2 -4 -2  0 -1 -4 -3 -3   16  20   2   9   0  13   4   1   0   0   1  26   0   0   1   5   2   0   0   0  0.44 inf
 227 N   -1  2  3 -1 -4  1 -2  5 -1 -5 -4  1 -3 -4 -3 -1 -2 -4 -4 -4    1  10  17   3   0   6   1  47   1   0   0  11   0   0   0   1   0   0   0   0  0.73 inf
 228 A    0 -1  1  3 -3  0  3 -2 -1 -3 -3  2 -2 -4  1  0  0 -4 -3 -3    9   1   6  20   0   2  21   1   1   0   1  20   0   0   5   7   5   0   0   1  0.39 inf
 229 N   -1  1  2  3 -3  0  0  0 -1 -4 -4  2 -3 -4  1  0  1 -4 -3 -3    4  10  12  23   0   3   4   9   0   0   0  13   0   0   6   5  11   0   0   0  0.34 inf
 230 R    1  4  2 -2 -3  1 -1 -2  0 -3 -2  2 -1 -4 -3  0  0 -4 -3 -3   17  35  11   1   0   7   2   1   2   1   2  10   2   0   0   4   4   0   0   0  0.43 inf
 231 V    0 -4 -4 -4  5 -4 -4 -4 -4  4  0 -4 -1 -2 -4 -3 -2 -4 -3  4    8   0   0   0  15   0   0   0   0  29   6   0   0   0   0   0   1   0   0  40  0.76 inf
 232 V    4 -3 -3 -1  0 -3 -3 -2 -3  0 -2 -3 -2 -1  0  0  1 -4 -3  3   43   0   0   4   2   0   0   0   0   3   0   0   0   2   3   6   7   0   0  28  0.46 inf
 233 I    2 -4 -4 -4 -1 -3 -4 -4 -4  4  1 -3  1 -2  0 -1 -1 -4 -3  3   18   0   0   0   1   0   0   0   0  36  13   0   2   0   4   4   2   0   0  20  0.48 inf
 234 C    2 -4 -3 -4  8 -3 -4 -1  1 -2 -3 -3  0 -4 -4 -1  3 -4 -3  1   22   0   0   0  33   0   0   5   4   0   0   0   3   0   0   1  21   0   0  10  0.84 inf
 235 Y   -4 -4 -5 -6 -2 -4 -5 -2  2 -3 -1 -5 -3  3 -6 -4 -3  7  8 -3    0   0   0   0   1   0   0   3   4   0   5   0   0  11   0   0   1  13  62   0  1.71 inf
 236 F   -3 -5 -5 -5  0 -5 -5 -5 -4  2  1 -5  0  7 -5 -4  0 -2  0  0    1   0   0   0   2   0   0   0   0  12   9   0   1  63   0   0   8   0   0   4  1.21 inf
 237 G   -2 -5 -3 -4 -5 -4 -5  7 -5 -6 -6 -4 -5 -1 -1 -3 -4 -5 -5 -6    0   0   0   0   0   0   0  93   0   0   0   0   0   3   3   0   0   0   0   0  1.96 inf
 238 E   -3 -3 -1  6 -5 -1  5 -4 -3 -5 -5 -2 -4 -5 -3 -2 -3 -5 -4 -5    0   0   0  51   0   0  45   0   0   0   0   0   0   0   0   0   0   0   0   0  1.44 inf
 239 G   -2 -4 -3 -3 -4 -4 -4  7 -4 -2 -5 -4 -4 -5 -4 -1 -3 -4 -5 -5    0   0   0   0   0   0   0  89   0   3   0   0   0   0   0   4   0   0   0   0  1.76 inf
 240 A    5 -3 -3 -3 -1  0 -2  2 -3 -3 -3 -2 -3 -4 -3  1 -1 -4 -3 -1   64   0   0   0   1   4   0  13   0   0   0   0   0   0   0  10   3   0   0   3  0.76 inf
 241 A    4 -1 -2 -3 -2 -2 -2 -2 -3 -3 -3 -2 -3 -4  0  1  4 -4 -3 -2   43   3   0   0   0   0   0   0   0   0   0   0   0   0   4  10  37   0   0   0  0.73 inf
 242 S    2 -3 -2 -3 -3 -2 -1 -3 -3 -4 -5 -3 -4  0 -3  6 -1 -5 -4 -4   15   0   0   0   0   0   3   0   0   0   0   0   0   4   0  77   0   0   0   0  1.19 inf
 243 E   -2  1 -2 -1 -6  2  6 -4 -1 -5 -5 -1 -4 -5 -3  0 -1 -5 -4 -5    1   8   0   0   0   8  73   0   1   0   0   1   0   0   1   5   2   0   0   0  1.28 inf
 244 G   -1 -1 -1 -3 -5 -3 -4  7 -1 -6 -6 -3 -5 -5 -3  1 -3 -5 -5 -5    3   4   1   0   0   0   0  80   2   0   0   0   0   0   1   9   0   0   0   0  1.47 inf
 245 D   -4 -4 -1  8 -6 -3 -1 -4 -4 -6 -6 -3 -6 -6  0 -1 -4 -7 -6 -6    0   0   0  91   0   0   1   0   0   0   0   0   0   0   4   3   0   0   0   0  2.08 inf
 246 A    2 -1 -5 -5 -2 -5 -5 -4 -4 -3 -2 -4 -3  8 -5 -3 -3  0  0 -3   24   3   0   0   1   0   0   0   0   0   0   0   0  69   0   0   1   1   1   0  1.45 inf
 247 H   -4 -3 -3 -4 -5 -2 -3 -5 10 -5 -5 -4 -4 -2 -5 -3 -4 -1  4  0    1   0   0   0   0   0   0   0  76   0   0   0   0   0   0   1   0   1  13   8  2.24 inf
 248 A    4  0 -2 -2 -3 -1  3 -1 -3 -3 -2 -2 -3 -4 -2  1  0 -4 -3 -2   49   4   0   0   0   0  24   3   0   0   3   0   0   0   0   7   6   0   0   2  0.55 inf
 249 G    4 -4 -3 -3 -3 -3 -1  5 -4 -4 -4 -3 -4 -1 -3 -1 -3 -4 -4 -3   49   0   0   0   0   0   3  43   0   0   0   0   0   3   0   1   0   0   0   0  1.02 inf
 250 F   -3 -4 -5 -5  0 -4 -4 -5 -4  1  4 -4  4  3 -1 -4 -1 -3 -2  0    0   0   0   0   2   0   0   0   0   6  54   0  12  15   3   0   4   0   0   3  0.72 inf
 251 N   -3 -3  7 -1 -4 -2 -3 -2 -2 -4 -2  0 -3 -5 -4  0  1 -6 -4 -1    0   0  70   0   0   0   0   2   0   0   5   4   1   0   0   4  10   0   0   4  1.23 inf
 252 F   -2 -5 -5 -6  2 -5 -5 -5 -4  1  0 -5  3  8 -5 -4 -3 -1  0 -2    4   0   0   0   4   0   0   0   0   7   4   0   9  68   0   1   1   0   0   1  1.41 inf
 253 A    6 -3 -3 -4 -3  0 -3  0 -4 -4 -4 -1 -3 -5 -3 -1 -2 -5 -4 -3   86   0   1   0   0   3   0   5   0   0   0   3   0   0   0   2   0   0   0   0  1.26 inf
 254 A    4 -3 -2 -3 -3 -2 -2  3  1 -4 -4 -1  0 -4 -3  3 -1 -4 -3 -3   46   0   0   0   0   0   0  22   4   0   0   3   3   0   0  21   1   0   0   0  0.66 inf
 255 T    0 -3 -3 -4 -3 -1 -3 -4 -4 -1 -2 -1 -2 -4 -4 -2  5 -5 -3  5    8   0   0   0   0   3   0   0   0   0   1   3   0   0   0   0  40   0   0  45  0.80 inf
 256 L   -1  2 -3 -4 -3 -2 -3 -4  1 -1  2 -2  1  3 -4 -3 -2 -1  4  0    4  12   0   0   0   1   0   0   3   1  28   1   3  15   0   0   2   0  20   7  0.43 inf
 257 E   -2  3  2  2 -4  1  2  0  0 -4 -4  3 -3 -4 -2  0 -2 -4 -3 -4    1  20   9  10   0   6  16   7   2   0   0  21   0   0   1   8   0   0   0   0  0.45 inf
 258 C    3 -4 -3 -4  7 -3 -3  0 -4 -2 -2 -3 -3 -4 -2  1  1 -4 -4  1   33   0   0   0  29   0   0   5   0   1   1   0   0   0   2  11   9   0   0  10  0.75 inf
 259 P   -3 -1 -2 -4 -5  1 -3 -5 -2 -5 -2 -3 -4 -6  8 -3 -4 -6 -5 -5    0   3   2   0   0   8   0   0   1   0   4   0   0   0  81   0   0   0   0   0  2.21 inf
 260 I    1 -4 -2 -4  1 -3 -3 -4 -4  2 -1 -3 -1 -3  0  0  2 -4 -3  4   12   0   2   0   3   0   0   0   0  14   1   0   1   0   4   5  13   0   0  46  0.51 inf
 261 I   -3  0 -5 -5 -3 -4 -5 -5 -5  6  1 -4  1 -2 -5 -4 -2 -4 -3  4    0   8   0   0   0   0   0   0   0  54  10   0   2   0   0   0   0   0   0  26  0.93 inf
 262 F   -2 -5 -5 -6 -4 -5 -5 -5 -4  0  1 -5  0  8 -5 -1 -4  0  1 -2    3   0   0   0   0   0   0   0   0   5  15   0   1  69   0   4   0   1   1   0  1.40 inf
 263 F   -3 -4  2 -4  0 -3 -2 -4 -3  2  1 -4  1  5 -4 -3 -3 -2  0  2    1   0  13   0   2   0   3   0   0  17  11   0   4  37   0   0   0   0   0  13  0.59 inf
 264 C   -2 -5 -2 -5  9 -5 -5 -2  1  1 -3 -5 -3 -4  0 -3 -3 -5 -4  3    2   0   3   0  56   0   0   3   3   8   0   0   0   0   4   0   0   0   0  20  1.53 inf
 265 R   -3  6  0 -3 -5  4 -1 -4 -2 -2 -2  0 -3 -4 -4 -3 -1 -5 -4  1    0  53   4   0   0  22   1   0   0   1   3   1   0   0   0   0   2   0   0  11  0.95 inf
 266 N   -3 -3  8 -1 -5 -2 -3 -3 -2 -6 -6 -3 -5 -1 -5 -1 -3 -6 -4 -6    1   0  92   0   0   1   0   0   0   0   0   0   0   3   0   3   0   0   0   0  2.10 inf
 267 N   -4 -3  8  0 -6 -3 -3 -1 -2 -6 -6 -3 -5 -6 -5 -2 -3 -7 -5 -6    0   0  93   3   0   0   0   3   0   0   0   0   0   0   0   0   0   0   0   0  2.21 inf
 268 G   -2  0 -1 -3 -3  4 -2  5  0 -2 -3 -1 -3 -3 -4 -2 -3 -4 -4 -4    0   5   2   0   0  27   0  56   2   3   2   1   0   1   0   1   0   0   0   0  0.98 inf
 269 Y   -5 -5 -5 -6 -5 -4 -5 -5 -2 -4 -2 -5 -3  4 -6 -5 -4  9  7 -4    0   0   0   0   0   0   0   0   0   0   3   0   0  14   0   0   0  29  49   0  1.99 inf
 270 A    6 -4 -4 -4 -3 -3 -3 -2  3 -4 -4 -3 -3 -5 -3 -1 -2 -5 -4 -3   91   0   0   0   0   0   0   0   7   0   0   0   0   0   0   2   0   0   0   0  1.46 inf
 271 I   -4 -5 -5 -5 -4 -5 -6 -1 -6  8 -1 -5 -1 -3 -5 -5 -3 -5 -4  0    0   0   0   0   0   0   0   7   0  92   0   0   0   0   0   0   0   0   0   0  1.70 inf
 272 S   -1 -3 -2 -3 -4 -3 -3 -3 -4 -5 -5 -3 -4 -5 -3  7 -1 -5 -4 -4    0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  99   0   0   0   0  1.81 inf
 273 T   -2 -4 -3 -3 -3 -3 -3 -4 -4 -2 -3 -3 -2 -4  1  1  6 -5 -4  2    0   0   0   0   0   0   0   0   0   0   1   0   1   0   7   7  67   0   0  17  1.07 inf
 274 P   -3 -5 -4 -3 -3 -4 -4 -5 -1 -5 -5 -4 -4  3  8 -2 -3 -5 -1 -5    0   0   0   1   1   0   0   0   2   0   0   0   0  12  79   3   0   0   2   0  2.14 inf
 275 T    0  1 -1 -3 -1  1 -2 -3 -2  0 -2 -1 -1 -1  1  1  3 -3 -1  1    7  10   1   0   1   9   0   0   0   6   1   0   1   3   7  12  30   0   2  11  0.27 inf
 276 S    0  0  0  0 -2  1  2  1  1 -2 -1  0 -2 -3  1  2  0 -4 -2 -2    8   4   3   3   0   5  13  11   5   1   7   5   0   0   7  23   4   0   1   1  0.19 inf
 277 E   -2  1 -2  2 -4  1  4 -4 -1  1 -2  2 -1 -1  1 -1 -2 -4 -3 -2    0   9   0  10   0   3  38   0   1  11   1  11   1   3   7   3   0   0   0   2  0.43 inf
 278 Q    1  1 -3 -3 -5  8 -1 -4 -2 -5 -5 -1 -3 -6 -4 -3 -3 -5 -4 -5   15   7   0   0   0  79   0   0   0   0   0   0   0   0   0   0   0   0   0   0  1.71 inf
 279 Y   -3 -1 -3 -4 -4 -3 -4  1 -1 -3  0 -3  1  3 -4  0  2 -1  6 -3    0   3   0   0   0   0   0  10   0   0   7   0   3  15   0   6  17   0  38   0  0.71 inf
 280 R    3  4 -1 -3 -3 -1 -2  1  0 -4 -4  2 -2 -4  1 -1 -2 -4 -3 -2   28  28   2   0   0   0   0  12   2   0   0  16   1   0   7   2   1   0   0   1  0.48 inf
 281 G    1 -3 -2 -3 -4 -2 -2  5 -2 -5 -5 -3 -4 -5 -3  3 -1 -5 -4 -4   12   0   0   0   0   1   2  53   1   0   0   0   0   0   0  27   3   0   0   0  0.96 inf
 282 D   -1  0  0  6 -4 -1  1 -3 -3 -4 -1  1 -3 -4 -1 -1  0 -5 -4 -3    4   4   2  52   0   2   8   1   0   0   7   8   0   0   3   3   7   0   0   0  0.71 inf
 283 G    0 -4 -2 -3 -4 -3 -4  5 -4 -4 -4 -3 -4 -5 -4 -1  4 -5 -5 -3    7   0   0   0   0   0   0  55   0   0   0   0   0   0   0   0  38   0   0   1  1.18 inf
 284 I    0 -5 -5 -5 -3 -5 -5 -5 -5  6  1 -4 -1  3 -5 -4 -3 -4 -1  2    7   0   0   0   0   0   0   0   0  62  10   0   0  14   0   0   0   0   1   7  0.96 inf
 285 A    6 -4 -4 -4 -3 -3 -3  0 -4 -3 -3 -3 -3 -3 -3 -1 -2 -5 -3  0   86   0   0   0   0   0   0   5   0   1   2   0   0   1   0   0   0   0   0   6  1.24 inf
 286 A    3 -2 -2 -1 -1  4 -1  1 -2 -1 -3 -2 -2 -4  1  2  0 -4 -3 -1   30   0   0   2   1  22   1   8   0   3   1   0   0   0   5  18   6   0   0   3  0.38 inf
 287 R   -4  7  0 -3 -6 -1 -2 -4 -3 -5 -5  4 -4 -5 -4 -3 -3 -5 -4 -5    0  63   4   0   0   0   1   0   0   0   0  32   0   0   0   0   0   0   0   0  1.50 inf
 288 G    4 -4 -3 -3 -4 -3 -4  6 -4 -5 -5 -3 -4 -5 -4  0 -3 -5 -5 -4   37   0   0   0   0   0   0  57   0   0   0   0   0   0   0   6   0   0   0   0  1.21 inf
 289 P   -1 -2 -3 -3 -3 -1 -2 -4  0  2  1 -2 -1 -2  5 -1 -1 -4 -2  2    4   2   1   0   0   3   1   0   3  15  12   1   1   1  31   2   2   0   1  19  0.54 inf
 290 G    4 -4 -3 -3 -3 -3 -3  5 -4 -5 -5 -3 -2 -5 -3  0 -3 -5 -5 -4   39   0   0   0   0   0   0  55   0   0   0   0   1   0   0   6   0   0   0   0  1.16 inf
 291 Y   -1 -4 -5 -6  1 -4 -5 -5  0 -4 -2 -5 -3  2 -5 -3 -4 -1  9 -2    6   0   0   0   3   0   0   0   1   0   4   0   0   6   0   1   0   0  79   2  1.95 inf
 292 G   -2 -4 -3  0  2 -4 -4  7 -2 -6 -6 -3 -5 -6 -5 -3 -4 -5 -5 -6    0   0   0   4   4   0   0  89   1   0   0   1   0   0   0   0   0   0   0   0  1.83 inf
 293 I   -3 -5 -5 -5 -3 -4 -5 -6 -5  6  1 -5  4  2 -5 -4 -3 -4 -2  1    0   0   0   0   0   0   0   0   0  64   8   0  13  10   0   0   0   0   0   5  1.13 inf
 294 M    1  0 -1  1 -4 -1  1 -3  2 -2 -2  0  3 -3  4 -1 -1 -4  1 -2   12   6   2  11   0   1   9   0   6   0   1   5  13   0  25   1   2   0   5   1  0.43 inf
 295 S    1 -3 -2 -3 -2 -2 -3  4 -3 -3 -4 -2 -3 -3 -3  3  3 -4 -3 -2   11   0   0   0   1   0   0  30   0   1   0   0   0   1   0  31  23   0   0   2  0.67 inf
 296 I   -2 -4 -5 -5 -3 -4 -3 -5 -5  6  2 -4  0 -1 -4 -4 -2 -4 -1  3    3   0   0   0   0   0   2   0   0  53  21   0   1   1   0   0   0   0   2  18  0.85 inf
 297 R   -4  7 -3 -4 -6  2 -2 -5 -3 -5 -2  0 -4 -5  0 -3 -4 -5 -4 -4    0  80   0   0   0  11   0   0   0   0   4   0   0   0   4   0   0   0   0   1  1.63 inf
 298 V   -3 -5 -5 -6 -1 -5 -5 -6 -5  1 -1 -5 -2 -2 -5 -4 -3 -5  1  7    0   0   0   0   1   0   0   0   0   5   0   0   0   1   0   0   0   0   4  89  1.49 inf
 299 D   -5 -4 -1  8 -6 -3 -1 -4 -4 -6 -6 -4 -6 -6 -4 -3 -4  3 -5 -6    0   0   0  96   0   0   0   0   0   0   0   0   0   0   0   0   0   4   0   0  2.30 inf
 300 G   -2 -5 -3 -4 -5 -4 -5  7 -5 -7 -6 -4 -5 -6 -5 -3 -4 -5 -6 -6    0   0   0   0   0   0   0 100   0   0   0   0   0   0   0   0   0   0   0   0  2.25 inf
 301 N   -3 -3  8 -1 -4 -1 -3 -2 -2 -4 -3 -3  4 -4 -4 -2  0 -5 -4 -4    1   0  76   0   0   1   0   1   0   0   1   0  13   0   0   1   4   0   0   0  1.54 inf
 302 D   -4 -4 -1  8 -6 -3 -1 -4 -4 -5 -6 -3 -5 -6 -4 -3 -3 -6 -5 -5    0   0   0  96   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  2.22 inf
 303 V    1 -3 -3 -4 -2 -3 -3 -3 -3  2  1 -3  0  2  2 -2 -1 -3  1  3   14   0   0   0   0   0   0   1   0  13  11   0   1  11  11   0   2   0   4  31  0.34 inf
 304 F   -4 -3 -5 -6 -4 -4 -4 -5 -4  0  5 -5  0  5 -5 -4 -3  3 -1 -1    0   1   0   0   0   0   1   0   0   3  57   0   1  32   0   0   0   4   0   1  1.07 inf
 305 A    7  0 -4 -4 -3 -3 -3 -2 -4 -4 -4 -3 -2 -5 -3 -1 -3 -5 -4 -3   95   4   0   0   0   0   0   0   0   0   0   0   0   0   0   1   0   0   0   0  1.54 inf
 306 V   -1 -5 -5 -5 -2 -4 -5 -5 -5  0 -1 -4  1 -3 -5 -1 -1 -5 -4  7    5   0   0   0   1   0   0   0   0   1   0   0   4   0   0   4   1   0   0  85  1.31 inf
 307 Y   -4  0 -4 -5 -5 -3 -4 -5  4 -3 -1 -4 -1  1 -5 -4 -3  3  8 -3    0   5   0   0   0   0   0   0  12   0   6   0   1   3   0   0   1   4  67   1  1.68 inf
 308 N    2 -1  3 -1 -3  1  1 -2  0 -3 -2  0 -1 -1 -3  0 -1 -3  1 -2   28   3  23   0   0   7  10   0   2   0   4   6   1   3   0   5   1   0   6   1  0.28 inf
 309 A    5 -4 -4 -4 -1 -3 -2 -2 -4 -2 -3 -3 -3 -3 -3 -1  0 -4  1  2   68   0   0   0   1   0   1   1   0   0   0   0   0   0   0   0   5   0   5  18  0.85 inf
 310 T    0 -3 -3 -3 -2 -3 -3 -4 -4 -1 -3 -3  2 -4  0  0  6 -5 -4  2    5   0   0   0   0   0   0   0   0   1   0   0   5   0   4   5  60   0   0  18  0.88 inf
 311 K   -1  4 -2 -3 -2  2  0 -3  1 -1 -2  5 -2 -4 -3 -1 -1 -4 -3 -3    3  23   0   0   1  10   2   1   3   4   4  43   0   0   0   3   2   0   0   1  0.63 inf
 312 E    0  1 -1  0 -4  1  4 -1 -1 -3 -3  1 -2 -2 -3 -1 -1  6 -1 -3    7   7   1   4   0   5  36   5   1   1   2  11   1   1   0   2   2  15   1   0  0.57 inf
 313 A    6 -4 -4 -4  3 -3 -3 -2 -4 -4 -4 -3 -2 -5 -3 -1 -3 -5 -4 -3   92   0   0   0   5   0   0   1   0   0   0   0   1   0   0   0   0   0   0   0  1.50 inf
 314 R    1  7 -3 -4 -4 -1 -2 -4 -3 -2 -1  0 -2 -3 -4 -3 -2 -5 -4  1   11  66   0   0   0   0   1   0   0   2   5   2   0   0   0   0   1   0   0  11  1.05 inf
 315 R   -1  4 -1  2 -5  1  5 -3 -1 -5 -4  2 -3 -5 -3 -1 -2 -5 -4 -4    6  24   2  10   0   6  41   0   0   0   0   9   0   0   0   1   0   0   0   0  0.74 inf
 316 R   -2  6 -3 -4 -4 -1 -2 -4 -2  1  1  1  2 -1 -4 -3 -3 -4  1 -2    1  53   0   0   0   1   1   0   1   9  13   6   7   2   0   0   0   0   5   1  0.74 inf
 317 A    6 -4 -4 -4  3 -3 -3 -2 -4  0 -3 -3 -3 -4 -3 -1 -1 -5 -4 -1   82   0   0   0   6   0   0   1   0   5   0   0   0   0   0   1   2   0   0   2  1.20 inf
 318 V   -2  4 -3 -4 -3 -2 -3 -4 -2  2  2 -1 -1 -2 -4 -2 -2 -4 -3  3    2  29   0   0   0   0   0   0   1  11  21   2   0   0   0   1   0   0   0  31  0.51 inf
 319 A    2  1  2  0 -2  1  2 -1  0 -3 -3  1 -2 -4 -2  1  0 -4 -3 -1   26  10  11   4   0   5  15   2   2   0   1   8   0   0   0   8   5   0   0   5  0.24 inf
 320 E   -2 -2  3 -1 -3  1  4  4  1 -4 -4 -1 -3 -4 -2 -1 -1 -4 -3 -4    1   1  16   1   0   5  29  34   3   0   0   1   0   0   2   2   3   0   0   0  0.62 inf
 321 N   -1 -1  4  1 -3  1  2  1  2 -3 -1  0 -1 -2 -2  0 -2 -4 -3 -3    2   1  26   7   0   6  17  13   5   0   9   5   1   2   1   6   0   0   0   0  0.32 inf
 322 Q   -1  3 -2 -3 -2  3  0  4 -2 -4 -4  2 -3 -4 -3 -2 -2  3 -3 -4    2  17   0   0   1  16   4  40   0   0   0  13   0   0   0   1   1   4   0   1  0.69 inf
 323 P   -1 -5 -5 -4 -6 -4 -4 -4 -5 -6 -6 -4 -5 -7  9 -3 -4 -7 -6 -5    5   0   0   0   0   0   0   1   0   0   0   0   0   0  94   0   0   0   0   0  2.81 inf
 324 F   -1 -4 -3 -4 -2 -3 -4 -4 -4  1 -2 -3  0  3 -4 -1  4  3 -1  3    2   0   0   0   1   0   0   0   0   8   0   0   2  14   0   2  36   4   0  31  0.63 inf
 325 L   -3 -4 -5 -6 -2 -4 -5 -6 -5  0  6 -4  1  1 -5 -4 -1 -4 -3  0    1   0   0   0   0   0   0   0   0   1  81   0   3   5   0   0   4   0   0   5  1.11 inf
 326 I   -3 -5 -6 -6 -3 -5 -5 -6 -6  7  1 -5  0 -2 -5 -5 -3 -5 -3  3    0   0   0   0   0   0   0   0   0  77   6   0   1   1   0   0   0   0   0  15  1.40 inf
 327 E   -4 -3 -3 -1 -7 -1  7 -5 -3 -6 -6 -2 -5 -6  0 -3 -4 -6 -5 -5    0   0   0   0   0   0  96   0   0   0   0   0   0   0   4   0   0   0   0   0  2.00 inf
 328 A    5 -3 -3 -4  1 -3 -3 -2  1 -2 -1 -3 -1  0 -3  0  2  3  0 -2   59   0   0   0   3   0   0   0   3   1   5   0   1   5   0   2  12   5   3   0  0.64 inf
 329 M   -3 -3 -4 -5 -3 -3 -4 -5 -4  1  2 -4  8  1 -5 -1 -2 -4 -2  3    0   1   0   0   0   0   0   0   0   4  13   0  49   7   0   4   0   0   1  21  1.02 inf
 330 T   -1 -3 -2 -3  2  0 -3 -4 -4 -3 -4 -3 -3 -4  0  1  6 -5 -4 -2    4   0   0   0   4   5   0   0   0   0   0   0   0   0   4  11  71   0   0   1  1.13 inf
 331 Y   -5 -1 -5 -6 -5 -4 -5 -6 -1 -4 -4 -5 -4  2 -6 -5 -5  3  9 -4    0   4   0   0   0   0   0   0   0   0   0   0   0   3   0   0   0   3  89   0  2.51 inf
 332 R   -4  8 -3 -4 -6 -2 -3 -5 -3 -5 -5  0 -4 -5 -5 -3 -4 -5 -4 -5    0  97   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  2.23 inf
 333 I    0 -3 -3 -4 -2 -2 -3 -3 -2  3  1 -3  1  1 -3 -2 -1 -2  3  3   11   1   0   0   0   2   0   1   0  23  13   0   2   6   0   2   1   0  13  24  0.34 inf
 334 G    0 -4 -2 -2 -4 -3 -1  6 -2 -5 -5 -3 -4 -5 -4  1 -2 -4 -4 -4    7   0   0   1   0   1   4  74   1   0   0   0   0   0   0  11   1   0   0   0  1.29 inf
 335 H    2 -3 -2 -2 -4 -2 -3  1  8 -5 -5 -3 -4 -4  3 -2 -3 -5 -2 -4   20   0   0   2   0   0   0   9  49   0   0   0   0   0  18   1   0   0   0   0  1.26 inf
 336 H   -5 -3 -2 -4 -6 -3 -3 -5 11 -6 -6 -4 -4 -4 -5 -4 -5 -5 -1 -6    0   0   0   0   0   0   0   0  97   0   0   0   0   0   0   0   0   0   0   0  3.16 inf
 337 S   -1 -3 -2 -2 -3 -2 -3 -3 -3 -4 -4 -3 -4 -5 -3  6  3 -5 -4 -3    0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  75  22   0   0   0  1.29 inf
 338 T   -2 -3 -2 -3 -3 -3 -3 -4 -4 -3 -3 -3  2 -4 -3  1  7 -5 -4 -2    0   0   0   0   0   0   0   0   0   0   1   0   7   0   0   8  81   0   0   0  1.46 inf
 339 S    2 -3 -2 -3 -3 -2 -3 -2 -3 -4 -4 -3 -4 -5 -3  6 -1 -5 -4 -4   17   0   0   0   0   0   0   0   0   0   0   0   0   0   0  81   0   0   0   0  1.32 inf
 340 D   -4 -4 -1  8 -6 -3 -1 -4 -4 -6 -6 -3 -5 -6 -4 -3 -4 -6 -5 -6    0   0   0  97   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  2.29 inf
 341 D   -4 -4 -1  8 -6 -3  0 -4 -2 -5 -6 -3 -5 -6 -4 -3 -4 -6 -4 -5    0   0   1  94   0   0   2   0   1   0   0   0   0   0   0   0   0   0   1   0  2.17 inf
 342 S   -1 -3 -3 -2 -4 -3 -3 -3 -2 -5 -5 -3 -4 -5  6  5 -2 -1 -4 -4    1   0   0   1   0   0   0   0   1   0   0   0   0   0  45  49   0   1   0   0  1.42 inf
 343 S   -1 -2 -1 -3 -3 -2 -2 -2 -3 -3 -3 -1 -3  2 -3  4  5 -4 -3 -2    1   2   1   0   0   0   0   2   0   0   0   2   0   9   0  44  37   0   0   1  0.77 inf
 344 A    3  3 -2 -3 -3  0 -2  1 -2 -2 -2  2 -1 -3 -3 -1 -2 -2 -3  0   40  21   0   0   0   3   0   9   0   1   4  14   2   0   0   0   1   1   0   5  0.42 inf
 345 Y   -5 -4 -5 -6 -5 -4 -5 -6 -1 -4 -4 -5 -4  0 -6 -4 -4 -1 10 -4    0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0   0  97   0  2.78 inf
 346 R   -4  8 -3 -4 -6 -1 -3 -5 -3 -5 -5  0 -4 -5 -5 -3 -4 -5 -4 -5    0  96   0   0   0   1   0   0   0   0   0   0   0   0   0   0   0   0   0   0  2.19 inf
 347 S    1 -2  0  1 -3 -2 -1 -1 -2 -4 -4 -1 -3 -4  4  4  1 -4 -4 -3    9   1   2  10   0   1   1   3   0   0   0   1   0   0  23  39   9   0   0   0  0.67 inf
 348 V    1  2 -1  0 -3  1  0 -1 -2 -1 -2  2 -1 -3 -1  0 -1 -4 -3  2   17  11   1   7   0   6   5   2   0   1   1  17   1   0   1   8   2   0   0  20  0.18 inf
 349 D   -1 -1  0  5 -4  0  4 -1 -2 -3 -4 -1 -3 -4 -3 -1 -1 -5 -4 -1    4   1   2  41   0   2  29   3   0   1   0   3   0   0   0   4   2   0   0   6  0.72 inf
 350 E   -2 -3 -3  1 -5 -1  7 -4 -3 -3 -2 -2 -3 -5 -3 -2 -3 -3 -4 -4    1   0   0   5   0   0  83   0   0   2   4   0   0   0   0   0   0   0   0   0  1.48 inf
 351 V    0 -2 -1  0 -1 -2  0 -3 -2  2  0 -3  0 -1 -3 -1 -1  2 -2  4    6   2   3   6   1   0   8   1   1  10   5   0   2   1   0   5   0   3   0  45  0.31 inf
 352 N    0  1  3  2 -4  1  4 -2 -2 -4 -4  0 -3 -4 -3  0 -1 -4 -3 -3   10   7  17   9   0   4  36   2   0   0   1   5   0   0   0   7   2   0   0   1  0.51 inf
 353 Y    1  0 -1  1 -2  1  2 -2  4 -2 -2  1 -1 -1 -1  0 -1 -1  3 -1   13   6   2   8   0   4  14   0  12   2   2   8   1   1   2   5   2   1  13   3  0.19 inf
 354 W   -5 -1 -6 -6 -5 -5 -5 -5 -5 -4 -4 -5 -4  2 -6 -4 -5 12 -1 -5    1   4   0   0   0   0   0   0   0   1   1   0   0   7   0   1   0  82   0   0  3.45 inf
 355 D   -1  3  0  3 -4  1  1 -2 -2 -4 -3  3 -3 -4  3 -1 -1 -4 -3 -3    4  15   4  17   0   5   7   1   0   0   1  22   0   0  15   3   3   0   1   1  0.44 inf
 356 K    0  2 -1 -1 -3  2  2 -3 -2 -2  1  3 -1 -3 -2  0  0 -3 -3 -2    7  10   1   1   0   8  13   0   0   1  17  27   1   0   0   5   5   0   0   2  0.25 inf
 357 Q   -1  2 -1 -2 -2  3  0  2  0 -2 -2  3 -1 -3 -3 -1 -1 -3 -2 -2    4  13   1   1   1  18   4  18   3   1   3  23   1   1   0   2   4   0   0   3  0.31 inf
 358 D   -3  1  0  6 -2 -2  0  0 -2 -3 -4 -1 -4 -1 -3 -2 -2 -4 -3 -3    1   8   3  63   1   1   3   7   1   1   1   2   0   3   0   1   2   0   1   1  0.98 inf
 359 H   -1 -1  3  2  1 -1  0 -1  6 -2 -2 -1 -2 -2 -1  0 -1 -2 -1 -2    3   2  19  12   3   2   3   3  25   2   4   2   1   2   2   7   4   1   1   3  0.38 inf
 360 P   -3 -5 -5 -5 -6 -4 -4 -5 -5 -6 -6 -4 -6 -7  9 -4 -4 -7 -6 -5    1   0   0   0   0   0   0   0   0   0   0   0   0   0  99   0   0   0   0   0  3.08 inf
 361 I   -3 -5 -5 -5 -3 -5 -5 -6 -5  6  3 -5  0 -2 -5 -4 -3 -4 -3  2    1   0   0   0   0   0   0   0   0  63  23   0   1   0   0   0   0   0   0  13  1.14 inf
 362 S    1 -1  0  0 -2  0  1 -2  0 -1  0  0 -1 -2  1  2  1 -3 -2  0   10   3   4   5   0   2  10   1   2   3   9   4   1   0   5  21  12   0   0   9  0.12 inf
 363 R   -4  8 -3 -4 -6 -2 -3 -5 -3 -5 -5  1 -4 -6 -5 -4 -4 -6 -5 -5    0  95   0   0   0   0   0   0   0   0   0   4   0   0   0   0   0   0   0   0  2.23 inf
 364 L   -3 -4 -5 -6 -4 -4 -5 -5 -4 -1  4 -4  4  5 -5 -4 -3 -2  1  0    0   0   0   0   0   0   0   0   0   0  54   0  12  27   0   0   1   0   3   3  1.00 inf
 365 R   -3  6 -2 -3 -4  0  1 -2 -2 -5 -4  4 -3 -3 -4 -2 -3 -5 -2 -4    1  57   0   0   0   3  10   2   0   0   0  22   0   1   0   0   0   0   1   0  1.12 inf
 366 H    0  3  1 -2 -4  1 -1 -3  4 -3  0  3 -2 -3 -3 -1  0 -4 -2 -2    6  18   7   0   0   6   0   0  14   0  11  25   0   0   0   2   6   0   0   2  0.38 inf
 367 Y   -4 -3 -4 -5 -5 -4 -4 -5  6 -4 -2 -4 -3  4 -5 -4 -4  7  7 -4    1   1   0   0   0   0   0   0  21   0   3   0   0  19   0   0   0  16  39   0  1.61 inf
 368 L   -4 -4 -6 -6 -2 -4 -5 -6 -5  0  6 -5  5 -2 -5 -5 -3 -4 -3  0    0   0   0   0   1   0   0   0   0   3  79   0  15   0   0   0   0   0   0   3  1.30 inf
 369 L   -2  0 -2 -1 -3  0  4 -4 -3  2  1  0  2 -2 -3 -2  0 -4 -3  1    1   5   0   1   0   3  32   0   0  19  14   5   5   1   0   0   5   0   0   9  0.32 inf
 370 S    1  1  2  1 -3  0  0  0  0 -3 -3  2 -3 -3 -2  2 -1 -4 -2 -3   11  10  14   8   0   3   4   7   2   0   2  13   0   0   0  22   2   0   0   1  0.29 inf
 371 Q   -2  4  0 -2 -4  3  0 -4  0 -1 -1  4 -1 -3 -3 -2 -1 -4 -3 -3    0  24   4   0   0  17   4   0   2   4   8  31   1   0   0   1   3   0   0   0  0.55 inf
 372 G   -2 -3  0 -1 -5 -2 -2  7 -4 -6 -6  0 -5 -5 -4 -2 -3 -5 -5 -5    1   1   4   3   0   1   2  81   0   0   0   5   0   0   0   1   0   0   0   0  1.50 inf
 373 W   -1 -2 -5 -3 -1 -2 -1 -4 -1  1  3 -3  0 -1 -5 -4 -4 10 -1 -1    6   2   0   1   1   1   6   0   1   8  28   1   1   0   0   0   0  39   1   3  1.24 inf
 374 W   -6 -6 -7 -8 -5 -5 -6 -6 -6 -3  1 -6 -3  1 -7 -6 -5 12  0 -5    0   0   0   0   0   0   0   0   0   2  12   0   0   4   0   0   1  80   2   0  3.43 inf
 375 D   -1 -3  3  5 -1 -2 -1  0 -3 -4 -5 -2 -4 -5 -3  4  1 -5 -4 -4    3   0  14  35   1   0   0   5   0   0   0   0   0   0   0  33   9   0   0   0  0.79 inf
 376 E   -2 -2 -1  4 -5  0  6 -3 -3 -5 -4 -1 -3 -5 -1 -2 -3 -5 -4 -4    3   1   1  19   0   3  63   1   0   0   1   2   0   0   3   1   0   0   0   1  1.11 inf
 377 E    1 -2 -1  2 -5  1  6 -2 -2 -5 -5  1 -3 -5 -3 -1 -2 -5 -4 -3   14   0   2  13   0   4  55   2   0   0   0   6   0   0   0   1   1   0   0   1  0.87 inf
 378 Q   -1  3 -2  1 -4  4  3 -3  0 -4 -3  2 -1 -4 -3 -1 -1  2 -3 -3    6  15   0   6   0  21  27   0   1   0   2  12   2   0   0   1   2   4   0   1  0.54 inf
 379 E   -1 -2 -1  3 -5  0  6 -4  5 -4 -5 -2 -4 -4 -3 -1 -2 -5 -3 -1    3   0   1  14   0   2  57   0  14   1   0   0   0   1   0   2   1   0   0   5  1.02 inf
 380 K    1  1  1  0 -4  2  2 -2 -2 -2 -3  3 -2 -4 -2  0  0 -4 -3 -2   14   6   8   4   0   7  16   1   0   2   1  29   1   0   1   6   4   0   0   1  0.36 inf
 381 A    3 -1 -1  0 -3  2  3 -2 -1 -3 -3  1 -3 -4 -3  0  1 -4 -3 -2   33   1   1   5   0   9  26   0   1   1   2   8   0   0   0   5   7   0   0   1  0.44 inf
 382 W    1 -2 -4 -4 -2 -1 -2 -3 -1  1  3 -3  1  0 -4 -2  0  7 -1  1   13   2   0   0   1   2   1   1   2   8  30   1   4   3   0   1   5  16   1  11  0.44 inf
 383 R   -1  4 -2 -1 -4  2  1 -3 -1  1 -1  1 -1 -3 -3 -1 -1 -1 -1  0    3  35   0   3   0  10  11   1   1   9   3   8   1   0   0   1   2   1   2   8  0.38 inf
 384 K    2  0 -1  2 -4  0  3 -2 -2 -4 -3  4 -2 -4 -3  0 -1 -5 -4 -3   21   4   2  10   0   2  22   1   0   0   1  29   0   0   0   5   3   0   0   0  0.49 inf
 385 Q   -1  1  1  1 -4  4  4 -3 -1 -4 -4  2 -3 -5 -3  1 -1 -4 -3 -4    4   6   5   6   0  25  30   1   1   0   0  10   0   0   0  10   4   0   0   0  0.62 inf
 386 S    2 -3 -2 -3 -1 -2 -1 -3 -2  2  1 -2  0  1 -3  1  0 -1  1  2   19   0   1   0   1   0   3   0   1  14  16   0   2   5   0  13   4   1   5  15  0.17 inf
 387 R   -1  6  0 -1 -5  1  0 -3 -2 -4 -2  3 -1 -5 -4 -2 -1 -5 -4 -3    4  48   3   4   0   5   6   0   0   0   3  21   2   0   0   1   3   0   0   1  0.80 inf
 388 R    1  1  0  2 -4  2  3 -2 -2 -4 -4  4 -2 -5 -3 -1 -1 -4 -3 -3   16   8   3   9   0   7  20   1   0   1   0  31   0   0   0   3   2   0   0   0  0.51 inf
 389 K   -1  0 -1  2 -4  2  4 -3 -2 -3 -1  1 -2 -3 -3 -1  0 -4 -2 -3    5   3   1  12   0  10  40   1   0   1   7  10   1   1   0   2   5   0   1   1  0.50 inf
 390 V   -2 -5 -5 -6 -3 -5 -5 -6 -5  4  0 -5  2 -3 -5 -4 -2 -5 -3  6    0   0   0   0   0   0   0   0   0  22   5   0   5   0   0   0   1   0   0  67  1.21 inf
 391 M    0  0 -2 -1 -3 -2 -1 -3 -2  1  3  1  4 -2 -4 -2 -1 -4 -3 -1    7   5   1   4   0   1   4   0   1   8  39  10  15   0   0   2   2   0   0   2  0.34 inf
 392 E    3  1 -1  1 -4  2  3 -3 -1 -3 -4  2 -3 -4 -3  0  0 -4 -3 -3   26   6   1   7   0  12  22   0   1   1   0  17   0   0   0   3   4   0   0   0  0.47 inf
 393 A    5 -3 -3 -3 -1 -1  1 -2 -3 -3 -3 -1 -1 -4 -3  1  0 -5 -4 -1   68   0   0   0   1   2   8   1   0   0   1   2   1   0   0   7   4   0   0   3  0.84 inf
 394 F   -3 -3 -4 -5 -3  1 -4 -4 -3  3  2 -4  2  5 -4 -3 -2 -1  0  1    1   0   0   0   0   8   0   0   0  20  22   0   6  27   0   0   1   0   2  11  0.57 inf
 395 E    1  1 -1 -1 -4  1  3 -1 -1 -3 -3  4 -2 -4 -3  0  0 -4 -3 -2   10   6   2   2   0   6  18   3   1   0   1  38   0   0   0   5   5   0   0   2  0.49 inf
 396 Q    2  2 -1  0 -3  2  4 -3 -1 -2 -3  1 -3 -4 -3 -1 -1 -4 -2  0   17  10   1   2   0  12  30   1   1   1   1  10   0   0   0   1   3   0   1   8  0.40 inf
 397 A    6 -4 -4 -4 -2 -1 -3 -1 -2 -3 -3 -3  0 -4 -3  0 -2 -5 -1  0   76   0   0   0   0   3   0   2   1   0   1   0   3   0   0   6   0   0   2   6  1.08 inf
 398 E   -3 -3 -2  1 -6  0  7 -4 -3 -5 -5 -2 -5 -6 -4 -2 -4 -6 -5 -4    2   0   0   7   0   2  86   0   0   0   1   1   0   0   0   1   0   0   0   1  1.76 inf
 399 R    2  3  0 -2 -4  1  0 -2 -2 -4 -3  4 -2 -4 -3  1 -1 -5 -3 -3   18  20   3   1   0   4   5   2   0   0   1  34   0   0   0   9   2   0   0   1  0.55 inf
 400 K   -1  0 -1 -1 -3  0  1 -3  1  0  1  2  1 -1 -3 -1  0 -1  1  1    5   3   3   1   0   2  10   0   5   7  13  20   4   2   0   2   7   1   6   9  0.09 inf
 401 P   -2 -2 -3 -2 -4 -1  1  2 -3 -4  0  2 -3 -4  6 -1 -3 -5 -4 -4    2   1   0   1   0   2   9  15   0   0  11  17   0   1  39   2   0   0   0   0  0.79 inf
 402 K   -1  2 -2 -2 -5 -1 -1 -4  2 -3 -2  6 -2 -5  1 -1 -1 -5 -4 -3    3  11   0   1   0   1   1   0   5   1   3  59   1   0   6   2   4   0   0   1  0.88 inf
 403 P   -1 -4 -4 -4 -1  1 -3 -3  1 -5 -4 -3 -4 -5  7 -1 -3  2 -2 -2    6   0   0   0   2   8   0   2   3   0   1   0   0   0  67   3   1   3   1   3  1.65 inf
 404 N    0 -1  3  1 -3 -1  0 -1  1 -4 -4  1 -2 -4  4  2 -1 -5 -3 -3    9   1  19   7   0   1   3   3   3   0   0   8   1   0  25  16   2   0   0   1  0.55 inf
 405 P   -1 -3 -4 -4 -3 -3 -4 -5 -4  2  2 -3  1 -1  4 -3 -2  3 -2  3    4   1   0   0   0   0   0   0   0  12  27   0   3   2  19   0   1   5   1  25  0.57 inf
 406 N    0  2  2  1 -3  1  2  0  0 -3 -3  1 -2 -4 -2  1  1 -4 -3 -2   10  11  12   8   0   5  18   5   2   1   1   8   0   0   1   9   8   0   0   2  0.27 inf
 407 L   -1 -2  0  3 -2  0  3 -1  0 -3  0 -2 -2 -3 -3  1  1 -1 -2 -2    3   0   3  19   0   1  25   4   2   0  12   0   1   1   0  14  11   1   1   1  0.32 inf
 408 L   -2 -4 -5 -6 -2 -4 -5 -6 -5  2  4 -4  7 -2 -5 -4 -3 -4 -3  0    3   0   0   0   0   0   0   0   0  13  45   0  36   1   0   0   0   0   0   2  1.17 inf
 409 F   -5 -6 -6 -6 -2 -6 -6 -6 -1  1 -1 -6  1  8 -6 -5 -5  0  0 -1    0   0   0   0   1   0   0   0   2   8   2   0   4  80   0   0   0   1   1   2  1.95 inf
 410 S   -1  0  0  3 -4  0  4 -3 -2 -4 -4  0 -3 -5 -3  2  2 -5 -3 -3    4   3   4  17   0   2  32   1   0   0   1   4   0   0   0  19  12   0   0   0  0.56 inf
 411 D   -4 -4  0  7 -4 -3 -1  0  2 -2 -5 -3 -5 -3 -4 -3 -4 -5  1 -4    0   0   4  71   0   0   1   7   5   4   0   0   0   1   0   0   0   0   6   0  1.43 inf
 412 V   -3 -5 -6 -6 -2 -5 -5 -6 -2  0 -1 -5  3 -3 -5 -4 -2 -6 -4  7    1   0   0   0   1   0   0   0   1   1   1   0   8   0   0   0   1   0   0  87  1.58 inf
 413 Y   -5 -5 -5 -6 -6 -5 -5 -6 -1 -4 -4 -5 -4  4 -6 -5 -5  1  9 -4    0   0   0   0   0   0   0   0   0   0   0   0   0  14   0   0   0   1  84   0  2.59 inf
 414 Q    2  0 -1  3 -4  2  3 -2  1 -4 -4  2 -3 -3 -3 -1 -2 -4 -2 -3   21   5   0  19   0   7  21   2   4   0   0  15   0   1   0   2   0   0   1   0  0.47 inf
 415 E   -2 -2 -1  2 -5  1  5 -3 -1 -3 -4  1 -3 -4 -3 -2  1 -5 -3 -1    2   0   2  13   0   4  54   1   1   1   0   7   0   0   0   1   8   0   0   4  0.82 inf
 416 M   -3 -3 -4 -4 -4 -2  0 -5 -4  0  1 -1  7 -3  4 -3 -2 -4 -4  0    1   1   0   0   0   1   6   0   0   4  14   4  42   0  21   0   2   0   0   6  0.95 inf
 417 P   -3 -4 -3  0 -5 -3 -4 -5 -2 -3 -1 -4 -4 -5  7 -2  3 -6 -5 -4    0   0   0   5   0   0   0   0   1   2   6   0   0   0  61   2  23   0   0   0  1.61 inf
 418 A    1 -1 -2 -2 -4  1  1 -3 -3 -4 -3  0 -4 -2  5 -1 -2  7 -1 -3   15   2   1   2   0   6   8   0   0   0   2   4   0   1  32   5   1  19   1   1  0.92 inf
 419 Q   -2  2  3  0 -5  2  1 -3  7 -3 -2 -2 -2 -3 -3 -2 -1 -5 -2 -3    2  10  18   5   0  10   7   0  35   1   3   0   1   1   0   1   3   0   0   1  0.78 inf
 420 L   -3 -5 -6 -6 -4 -1 -5 -6 -5  2  6 -5  0 -2 -5 -5 -3 -4 -4  0    2   0   0   0   0   3   0   0   0  10  82   0   1   0   0   0   0   0   0   2  1.26 inf
 421 R   -1  4 -2 -2 -2  4  1 -4  0 -1 -1  3 -1 -3 -3 -2 -1 -2 -3 -1    5  25   1   1   1  20   8   0   2   4   5  19   1   0   0   1   2   0   0   5  0.45 inf
 422 K    0  3 -2 -1 -5  2  5 -4 -2 -5 -5  3 -3 -5 -3 -1 -3 -5 -4 -4    6  17   1   2   0   6  47   0   0   0   0  19   0   0   0   2   0   0   0   0  0.93 inf
 423 Q   -3 -2 -3 -4 -6  9 -1 -5 -2 -6 -6 -2 -4 -7 -5 -3 -4 -6 -5 -6    2   0   0   0   0  97   0   0   1   0   0   0   0   0   0   0   0   0   0   0  2.57 inf
 424 Q   -2  4 -2 -3 -3  3  1 -4 -2 -2  0  1  4 -1 -4 -2 -3 -2  2 -2    1  28   0   0   0  17   8   0   0   1  11   9  13   2   0   1   0   0   8   1  0.53 inf
 425 E    0  1  0  3 -4  3  4 -3  0 -4 -3  2 -3 -5 -3 -1 -1 -5 -4 -3   10   7   3  15   0  14  32   1   1   0   1  11   0   0   0   1   2   0   0   0  0.56 inf
 426 S    0 -2 -1  0 -3  3  5 -1 -2 -1 -2 -1 -2 -3 -3  1 -2  0 -1 -3    8   1   1   2   0  15  41   4   0   5   4   1   1   0   0  10   0   1   2   1  0.51 inf
 427 L   -2 -4 -5 -5 -1 -4 -5 -5 -4  0  5 -4  4  2 -5 -3 -2 -1  3  1    2   0   0   0   1   0   0   0   0   2  56   0  11   7   0   1   1   0  12   7  0.80 inf
 428 A    1  2 -1 -1 -3  0  2 -2  0 -1  0  3  0 -2 -3 -1 -2 -1 -2 -1   14  11   1   2   0   3  16   1   2   3  12  26   2   2   0   1   0   1   0   2  0.25 inf
 429 R    1  4 -1  2 -4  2  3 -3 -1 -4 -4  1 -3 -5 -3  1 -2 -4 -3 -4   15  26   0  11   0   8  24   1   1   0   0   5   0   0   0   9   1   0   0   0  0.55 inf
 430 H   -3 -2 -2 -3 -4 -1  0 -4  8  1  0 -3 -1  1 -4 -2 -1  2  1 -1    1   2   0   0   0   2   7   0  50   8   8   0   1   5   0   2   5   3   4   3  0.99 inf
 431 L   -3  1 -4 -4 -3 -2 -3 -5 -3  3  4 -1  2  1 -3 -3 -2  1  0  1    0  10   0   0   0   1   1   0   0  18  44   3   5   4   1   0   0   2   3   9  0.48 inf
 432 Q    0  2  0  0 -4  3  4 -2 -1 -4 -3  4 -1 -4 -3 -1 -1 -4 -3 -4    6  11   3   5   0  13  27   2   0   0   1  27   1   0   0   2   2   0   0   0  0.56 inf
 433 T    0  3 -1 -2 -4  1  2 -3 -1 -3 -2  4 -2 -4 -3 -1  2 -4 -3 -3   10  19   1   1   0   4  12   0   1   0   3  30   0   0   0   1  19   0   0   1  0.49 inf
 434 Y   -2 -2  0 -4 -5 -2 -3 -5  6 -4 -4 -2 -3  2 -2 -2 -4  3  8 -4    2   1   6   0   0   0   1   0  19   0   0   3   0   5   2   2   0   3  56   0  1.42 inf
 435 G   -2 -1 -3 -3 -5 -2 -2  5 -2 -5 -5  2 -4 -5  5 -1 -3 -5 -5 -5    2   3   0   0   0   1   1  42   1   0   0  13   0   0  35   2   1   0   0   0  1.11 inf
 436 E   -2 -1  0  4 -5  2  5 -1  0 -5 -5  1 -4 -5 -2  0 -2 -5 -4 -4    2   2   4  25   0   7  42   3   1   0   0   8   0   0   1   4   0   0   0   0  0.76 inf
 437 H    1 -1  0  2 -2  0  3 -2  6 -3 -4 -1 -2 -1 -2 -1 -2 -4  0 -2   11   1   3  12   1   2  23   1  30   1   0   2   0   2   1   2   1   0   3   3  0.57 inf
 438 Y   -1 -3 -5 -5 -2 -4 -3 -5 -1 -4 -2 -4 -3  1 -5 -4 -3  4  9 -2    6   1   0   0   1   0   2   0   0   0   2   0   0   1   0   0   1   5  80   2  1.94 inf
 439 P   -3 -4  0  3 -5 -3 -2 -4 -4 -4 -1 -2 -4 -3  7 -3 -3 -6 -5 -4    0   0   4  19   0   0   1   0   0   0   8   2   0   1  64   0   1   0   0   0  1.58 inf
 440 L   -1 -3 -4 -4 -1 -1 -3 -4 -4  1  4 -2  2 -1 -2 -1  1 -3 -2  1    2   0   0   0   1   3   1   1   0   6  57   1   4   1   1   3   8   0   0  11  0.46 inf
 441 D   -2 -1  2  5 -4  0  3 -1  0 -4 -4  1 -3 -4 -3  1 -1 -4 -2 -4    1   2   8  35   0   1  24   4   1   0   0   9   0   0   0  11   1   0   1   0  0.59 inf
 442 H   -1  0  0  2 -4  3  2 -1  5 -3 -2  1 -2 -3 -1  0 -1 -4 -2 -2    2    3   3  11   0  15  18   3  19   0   5  12   0   0   2   6   0   0   0   1   0.37 inf
 443 F   -4 -4 -4 -5 -4 -3 -4 -5  5 -2 -1 -4 -2  7 -5 -4 -4 -1  5 -3    0    0   0   0   0   0   0   0  17   0   2   0   0  60   0   0   0   0  21   0   1.38 inf
 444 D   -1 -1 -1  3 -4  1  5 -3 -2 -3 -2  2 -3 -4 -2 -1 -2 -4 -3 -3    3    0   0  16   0   5  57   0   0   0   6  11   0   0   0   0   1   0   0   1   0.70 inf
 445 K   -2  3 -1 -1 -4  4  1 -3 -1 -4 -3  5 -2 -4 -2 -1 -1 -3 -2 -3    0   19   0   0   0  28   2   0   0   0   0  51   0   0   0   0   0   0   0   0   0.71 inf

                     K         Lambda
Standard Ungapped    0.1346     0.3196
Standard Gapped      0.0410     0.2670
PSI Ungapped         0.1713     0.3175
PSI Gapped           0.0524     0.2670



CLUSTAL 2.0.12 multiple sequence alignment


gi|39943658|ref|XP_361366.1|        ----MR--VRLPGAASSIGR---RCRNHGR--------------------
gi|164422564|ref|XP_960181.2|       ----MKRICRSSQRSPSLLRPLTPVTHQPR--------------------
gi|21355903|ref|NP_649905.1|        ---------------MSFLRKSVHLLGS----------------------
gi|158291301|ref|XP_312823.4|       -------------------------LSS----------------------
gi|11386135|ref|NP_000700.1|        --------MAVAIAAARVWRL-NRGLSQ----------------------
gi|148727347|ref|NP_001092034.      --------MAVAIAAARVWRL-NRGLSQ----------------------
gi|297277135|ref|XP_001101959.      --------MAVAIAAARVWRP-NRGLSQ----------------------
gi|73947481|ref|XP_866392.1|        --------MAVAAAAARVWGS-SRGLGQ----------------------
gi|27806229|ref|NP_776931.1|        MQGSAKMAMAVAVAVARVWRP-SRGLGR----------------------
gi|183396774|ref|NP_031559.3|       --------MAIVMSAAKIWRP-SRGLRQ----------------------
gi|77736548|ref|NP_036914.1|        --------MAVAMSAAKIWRP-SRGLRQ----------------------
gi|66773104|ref|NP_001019590.1      --------MAAARAVKKLYGIGLHAIRQN---------------------
gi|86563355|ref|NP_001033376.1      -------------------------MHR----------------------
gi|18415939|ref|NP_568209.1|        ----MALHLRSSFSSKSTLLNILRHNLGFGSRSHVTR--------HIRQI
gi|115487674|ref|NP_001066324.      ----MAPWRAAAMASSQLARRAARRLLSSQHRRHCAAPACPWLLGSAPPV
                                                                                      

gi|39943658|ref|XP_361366.1|        --------GAP-KIGSLHQTAPGSASSMRAASTLKQKP-----DSSFVSF
gi|164422564|ref|XP_960181.2|       --------LVPIAIQPSTTTTSKTVASRRHASSLSQRP-----DASHVMF
gi|21355903|ref|NP_649905.1|        ------------VARRQRHLKVIEGAISTAARDFSSKP-----SEDYANF
gi|158291301|ref|XP_312823.4|       ------------DAASQ--------------QQGASGP-----SSLHAKF
gi|11386135|ref|NP_000700.1|        --------AALLLLRQPGARGLARSHPPR--QQQQFSS-----LDDKPQF
gi|148727347|ref|NP_001092034.      --------AALLLLRRPGARGLARSHPRR--QQQQFSS-----LDDKPQF
gi|297277135|ref|XP_001101959.      --------AALLLLWRPGARGLARSHPHR--QQQQFSS-----LDDKPQF
gi|73947481|ref|XP_866392.1|        --------AGLLLLRRPWARGLARSHPQR-QEQQHFPS-----LDDKPQF
gi|27806229|ref|NP_776931.1|        --------TGLPLLRLLGARGLARFHPHRWQQQQHFSS-----LDDKPQF
gi|183396774|ref|NP_031559.3|       --------AALLLLGRSGVRGLARSHPSR-QQQQQFPS-----LDDKPQF
gi|77736548|ref|NP_036914.1|        --------AALLLLGRPGARGLARFHPSR-QQQQQFPS-----LDDKPQF
gi|66773104|ref|NP_001019590.1      --------TALKATTLLQQRGFRVNGVLR---QQSIDD-----SDEKPQF
gi|86563355|ref|NP_001033376.1      --------ALLNASRRVATVRSMASTVEG----DAFRL-----SEYSSKY
gi|18415939|ref|NP_568209.1|        LPHDPPLRGSQNPISRLCNT---MAEPETLSSFVQHEY---ANNHQVMDF
gi|115487674|ref|NP_001066324.      LAPSPVAAAAAGDRRGFCSVRRFTGESNAAAAVEEAENGLVAGGDQAIDF
                                                                                     :

gi|39943658|ref|XP_361366.1|        PGAVKSEFTTKFQFERPEQYPAMPTYRVVDQHGVVVDPEFEQDLNDEGVI
gi|164422564|ref|XP_960181.2|       PGAVKSAFCNTMTFEEPSKYDALPTYRAVDQHGQVVDPSFKPDLSDKEVI
gi|21355903|ref|NP_649905.1|        PGA-KAPFVSKLNLIQPEDYAPIPIYRVMDQDGYIADETQDPQLGREVVE
gi|158291301|ref|XP_312823.4|       PGALEASFVTTPKLALPESIEPIPIYRVMNSEGVIDDPSQEPNLEQATVQ
gi|11386135|ref|NP_000700.1|        PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVL
gi|148727347|ref|NP_001092034.      PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVL
gi|297277135|ref|XP_001101959.      PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVL
gi|73947481|ref|XP_866392.1|        PG-ASAEFIDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQEKVL
gi|27806229|ref|NP_776931.1|        PG-ASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVL
gi|183396774|ref|NP_031559.3|       PG-ASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVL
gi|77736548|ref|NP_036914.1|        PG-ASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVL
gi|66773104|ref|NP_001019590.1      PG-ASAEFIDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPQLSKETVL
gi|86563355|ref|NP_001033376.1      LGHRKAAFTEKLEIVNADDTPALPIYRVTNAVGDVIDKSQDPNFDEQTSL
gi|18415939|ref|NP_568209.1|        PG-GKVAFTPEIQFISESDKERVPCYRVLDDNGQLITNSQFVQVSEEVAV
gi|115487674|ref|NP_001066324.      PG-GKVSFVAEMNFLPESQRDRINCYRVLDDDGRTISGSRFQEVSKELAL
                                     *  .  *     :   .    :  **. :  *         ..      

gi|39943658|ref|XP_361366.1|        KLYEDMVAVSVMDSIMFDAQRQGRVSFYMVSAGEEAVCVGSASALEMRDV
gi|164422564|ref|XP_960181.2|       KLYHDMLTVSIMDLIMFDAQRQGRLSFYMVSAGEEAVCVGSASALSPEDV
gi|21355903|ref|NP_649905.1|        KMFRDMVLLNTMDKILYESQRQGRISFYMTNFGEEASHIGSAAALEMRDL
gi|158291301|ref|XP_312823.4|       KMFRDMVLLNTMDKILYESQRQGRISFYMTNFGEEASHIGSAAALSLEDW
gi|11386135|ref|NP_000700.1|        KLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
gi|148727347|ref|NP_001092034.      KLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
gi|297277135|ref|XP_001101959.      KLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
gi|73947481|ref|XP_866392.1|        KFYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDL
gi|27806229|ref|NP_776931.1|        KFYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDL
gi|183396774|ref|NP_031559.3|       KFYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDL
gi|77736548|ref|NP_036914.1|        KLYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDL
gi|66773104|ref|NP_001019590.1      NFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHIGSAAALDPSDL
gi|86563355|ref|NP_001033376.1      KMYKTMTQLNIMDRILYDSQRQGRISFYMTSFGEEGNHVGSAAALEPQDL
gi|18415939|ref|NP_568209.1|        KIYSDMVTLQIMDNIFYEAQRQGRLSFYATAIGEEAINIASAAALTPQDV
gi|115487674|ref|NP_001066324.      KMYNEMATLQVMDTIFFEAQRQGRISFYLTSHGEEAINIASAAALTIDDI
                                    :::  *  :. ** *::::*****:*** .  ***.  :.**:**   * 

gi|39943658|ref|XP_361366.1|        IFCQYREQGVYRHRGMTFRDFMNQLFANKYDPGQGRNMPVHYGSKELNMH
gi|164422564|ref|XP_960181.2|       VFCQYREQGVFKQRGFQLSDFMNQLFANHKDSGKGRNMPVHYGSKELNIH
gi|21355903|ref|NP_649905.1|        IYGQYREAGVLVWRGFRIDQFIDQCYGNTDDLGRGKQMPVHYGSRELNFV
gi|158291301|ref|XP_312823.4|       VYGQYREAGVLVWRGFTISDFINQCYGNAEDQGKGRQMPVHYGSRKLNFV
gi|11386135|ref|NP_000700.1|        VFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFV
gi|148727347|ref|NP_001092034.      VFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFV
gi|297277135|ref|XP_001101959.      VFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFV
gi|73947481|ref|XP_866392.1|        VFGQYREAGVLMYRDYPLELFMAQCYGNVSDPGKGRQMPVHYGCKDRHFV
gi|27806229|ref|NP_776931.1|        VFGQYREAGVLMYRDYPLELFMAQCYGNVSDLGKGRQMPVHYGCRERHFV
gi|183396774|ref|NP_031559.3|       VFGQYREAGVLMYRDYPLELFMSQCYGNVNDPGKGRQMPVHYGCKERHFV
gi|77736548|ref|NP_036914.1|        VFGQYREAGVLMYRDYPLELFMAQCYGNVSDPGKGRQMPVHYGCKERHFV
gi|66773104|ref|NP_001019590.1      VFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGSKDLNFV
gi|86563355|ref|NP_001033376.1      IYGQYREAGVLLWRGYTMENFMNQCYGNADDLGKGRQMPMHFGTKERNFV
gi|18415939|ref|NP_568209.1|        IFPQYREPGVLLWRGFTLQEFANQCFGNKSDYGKGRQMPVHYGSNKLNYF
gi|115487674|ref|NP_001066324.      VLPQYREPGVLLWRGFTLQEFANQCFGNKLDYGKGRQMPIHYGSNRLNYF
                                    :  **** **   *.  :  *  * :.*  * *:*::**:*:* .  :   

gi|39943658|ref|XP_361366.1|        TISSPLATQIPQASGAAYAMKMQRIANPDAPERVAVVYFGEGAASEGDFH
gi|164422564|ref|XP_960181.2|       TISSPLATQLPQAAGAAYALKIQRMQNPTVPPRVVAAYFGEGAASEGDFH
gi|21355903|ref|NP_649905.1|        TISSPLSTQMPQAVGAAYAMKLRPNND-----ACVVCYFGEGAASEGDAH
gi|158291301|ref|XP_312823.4|       TISSPLGTQIPQAAGAAYAFKLQPNNQ-----RCVITYFGEGAASEGDTH
gi|11386135|ref|NP_000700.1|        TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
gi|148727347|ref|NP_001092034.      TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
gi|297277135|ref|XP_001101959.      TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
gi|73947481|ref|XP_866392.1|        TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
gi|27806229|ref|NP_776931.1|        TISSPLATQIPQAVGAAYAAKRA-NAN-----RVVICYFGEGAASEGDAH
gi|183396774|ref|NP_031559.3|       TISSPLATQIPQAVGAAYAAKRA-NAN-----RIVICYFGEGAASEGDAH
gi|77736548|ref|NP_036914.1|        TISSPLATQIPQAVGAAYAAKRA-NAN-----QIVICYFGEGAASEGDAH
gi|66773104|ref|NP_001019590.1      TISSPLATQIPQAAGAAYAVKRE-NAN-----RVVICYFGEGAASEGDAH
gi|86563355|ref|NP_001033376.1      TISSPLTTQLPQAVGSAYAFKQQKDNN-----RIAVVYFGDGAASEGDAH
gi|18415939|ref|NP_568209.1|        TVSATIATQLPNAVGAAYSLKMD-KKD-----ACAVTYFGDGGTSEGDFH
gi|115487674|ref|NP_001066324.      TVSSPIATQLPHAVGAAYSLKMD-KKD-----ACAITYFGDGGTSEGDFH
                                   *:*:.: **:*:* *:**: *     :       .  ***:*.:**** * 

gi|39943658|ref|XP_361366.1|        AALNIAATRACPVIFICRNNGYSISTPSLEQYKGDGIASR-GVGYGIDTV
gi|164422564|ref|XP_960181.2|       AALNIAATRGCPAVFICRNNGYAISTPTLEQYRGDGIASR-GLGYGIETI
gi|21355903|ref|NP_649905.1|        AAFNFAATLGCPAILFCRNNGFAISTPSHEQYKGDGIAGRGPMGYGITTI
gi|158291301|ref|XP_312823.4|       AAFNFAATLDSPVIFFCRNNGFAISTPSKEQYRGDGIAGR-AAGYGMAAL
gi|11386135|ref|NP_000700.1|        AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
gi|148727347|ref|NP_001092034.      AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
gi|297277135|ref|XP_001101959.      AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAR--GPGYGIMSI
gi|73947481|ref|XP_866392.1|        AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
gi|27806229|ref|NP_776931.1|        AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGILSI
gi|183396774|ref|NP_031559.3|       AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
gi|77736548|ref|NP_036914.1|        AGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAAR-GPGYGIMSI
gi|66773104|ref|NP_001019590.1      AGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAAR-GPGYGLMSI
gi|86563355|ref|NP_001033376.1      AAFNFAATLKCPIIFFCRNNGYAISTPTSEQYGGDGIAGK-GPAYGLHTI
gi|18415939|ref|NP_568209.1|        AALNIAAVMEAPVLFICRNNGWAISTPTSDQFRSDGVVVK-GRAYGIRSI
gi|115487674|ref|NP_001066324.      AALNFAAVMEAPVIFFCRNNGWAISTPTSEQFRSDGAVIR-GQAYGMRSI
                                   *.:*::*.  .* :::*****::****: :*: .** .     .**: :: 

gi|39943658|ref|XP_361366.1|        RVDGNDIWAVRKATKKARELALENGGKPVLLECLTYRVGHHSTSDDSFAY
gi|164422564|ref|XP_960181.2|       RVDGNDFWAVREVTKRARELALQDGGKPVLIEAMTYRVSHHSTSDDSFAY
gi|21355903|ref|NP_649905.1|        RVDGTDVFAVYNAMKAAREYVLKE-NKPVVFEALAYRVGHHSTSDDSTAY
gi|158291301|ref|XP_312823.4|       RFDGTDVFATYNATKLAREYVLRE-NKPIVLEAMAYRIGHHSTSDDSTAY
gi|11386135|ref|NP_000700.1|        RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|148727347|ref|NP_001092034.      RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|297277135|ref|XP_001101959.      RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|73947481|ref|XP_866392.1|        RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|27806229|ref|NP_776931.1|        RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|183396774|ref|NP_031559.3|       RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|77736548|ref|NP_036914.1|        RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|66773104|ref|NP_001019590.1      RVDGNDVFAVYNATKEARRRAVAE-NQPFLIEAMTYRIGHHSTSDDSSAY
gi|86563355|ref|NP_001033376.1      RVDGNDLLAVYNATKEARRVALT--NRPVLIEAMTYRLGHHSTSDDSTAY
gi|18415939|ref|NP_568209.1|        RVDGNDALAMYSAVHTAREMAIRE-QRPILIEALTYRVGHHSTSDDSTRY
gi|115487674|ref|NP_001066324.      RVDGNDALAVYSAVHTAREMAIKE-GRPILVEALTYRVGHHSTSDDSTKY
                                    *.**.*  *  .. : **. .:    :*.:.*.::**:.********  *

gi|39943658|ref|XP_361366.1|        RARVEVEDWKRRDNPISRLRKWMESKDMWDDDKEKVMRDRLRKEILKAFS
gi|164422564|ref|XP_960181.2|       RAKVEVEDWKRRDNPIGRLRKWMEAKGIWDENMEREARDSIRRDILKAFS
gi|21355903|ref|NP_649905.1|        RPAEEIEIWNSVEHPISKLKRYMVHKGWFDETVENEYVKDIRKKVLKQIA
gi|158291301|ref|XP_312823.4|       RPAEELEVWNTVEHPIAKLKHYMLRRGWFDEAKENEFVKSVRKQVLSQIN
gi|11386135|ref|NP_000700.1|        RSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFE
gi|148727347|ref|NP_001092034.      RSVDEVNYWDKQDHPVSRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFE
gi|297277135|ref|XP_001101959.      RSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFE
gi|73947481|ref|XP_866392.1|        RSVDEVNYWDKQDHPISRLRHYLQSRGWWDDEQEKAWRKQSRKKVMEAFE
gi|27806229|ref|NP_776931.1|        RSVDEVNYWDKQDHPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFE
gi|183396774|ref|NP_031559.3|       RSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFE
gi|77736548|ref|NP_036914.1|        RSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFE
gi|66773104|ref|NP_001019590.1      RSVDEVNYWDKQDHPISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFE
gi|86563355|ref|NP_001033376.1      RSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEMEWQKEVKKRVLTEFA
gi|18415939|ref|NP_568209.1|        RSAGEIEWWNKARNPLSRFRTWIESNGWWSDKTESDLRSRIKKEMLEALR
gi|115487674|ref|NP_001066324.      RPVDEIEHWRTARDPISRYRKWVQGNGWWCDEDESELRNNVRQELLKAIQ
                                    *.  *:: *    .*: : :  :  .. : :  *    .  :: ::  : 

gi|39943658|ref|XP_361366.1|        EAEKEKKPPIRAMFEDVYEEMTPDLKKQMAELKDHIERYPEEYD-VGEFE
gi|164422564|ref|XP_960181.2|       QAEKEKKPAIRTMFEDVYEEMTPEIKAQMKELKEHLEQYPEEYD-LGDFE
gi|21355903|ref|NP_649905.1|        VSEKKLKPNWREMFEGVYAEMPDHLIEQRSELEKHIEAHKEHYP-LKDFE
gi|158291301|ref|XP_312823.4|       QSERILKPDWREMFQDVYAEMPAHLKEQLRAMEEHVEQHREHYP-LKDFK
gi|11386135|ref|NP_000700.1|        QAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LDHFD
gi|148727347|ref|NP_001092034.      QAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LDHFD
gi|297277135|ref|XP_001101959.      QAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LEHFD
gi|73947481|ref|XP_866392.1|        QAERKPKPNPNLLFSDVYQEMPTQLRKQQEALARHLQTYGEHYP-LDHFE
gi|27806229|ref|NP_776931.1|        QAERKLKPNPSLIFSDVYQEMPAQLRKQQESLARHLQTYGEHYP-LDHFE
gi|183396774|ref|NP_031559.3|       QAERKLKPNPSLLFSDVYQEMPAQLRRQQESLARHLQTYGEHYP-LDHFD
gi|77736548|ref|NP_036914.1|        QAERKLKPNPSLLFSDVYQEMPAQLRRQQESLARHLQTYGEHYP-LDHFD
gi|66773104|ref|NP_001019590.1      RAERRLKPNPDLMFTDVYDEMVPHIAKQKDSMWRHVQQYKEHYP-LDHYE
gi|86563355|ref|NP_001033376.1      AAEKRKKAHYHDLFEDVYDELPLRLRRQRDELDAHVAEYKEHYPMLETLQ
gi|18415939|ref|NP_568209.1|        VAEKTEKPNLQNMFSDVYDVPPSNLREQELLVRQTINSHPQDYP--SDVP
gi|115487674|ref|NP_001066324.      VAERMPKPPLAELFTDVYDEVPSNLREQERLLRDTIKKHPADYP--ADVH
                                     :*:  *.    :* .**      :  *   :   :  :  .*        

gi|39943658|ref|XP_361366.1|        GGKDSLKP
gi|164422564|ref|XP_960181.2|       GGKDSLAR
gi|21355903|ref|NP_649905.1|        K-------
gi|158291301|ref|XP_312823.4|       Q-------
gi|11386135|ref|NP_000700.1|        K-------
gi|148727347|ref|NP_001092034.      K-------
gi|297277135|ref|XP_001101959.      K-------
gi|73947481|ref|XP_866392.1|        K-------
gi|27806229|ref|NP_776931.1|        K-------
gi|183396774|ref|NP_031559.3|       K-------
gi|77736548|ref|NP_036914.1|        K-------
gi|66773104|ref|NP_001019590.1      K-------
gi|86563355|ref|NP_001033376.1      SKP-----
gi|18415939|ref|NP_568209.1|        L-------
gi|115487674|ref|NP_001066324.      I-------
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