Difference between revisions of "Sequence-based mutation analysis HEXA/Mutation Summary"
From Bioinformatikpedia
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| − | === Visualisation of the mutations === |
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| − | {| border="1" style="text-align:center; border-spacing:0;" |
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| − | |SNP-id |
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| − | |mutation codon |
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| − | |picture original aa |
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| − | |picture mutated aa |
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| − | |combined picture |
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| − | |- |
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| − | |rs4777505 |
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| − | |Asn -> Ser |
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| − | |[[Image:N29_2.png|thumb|150px|Amino acid Asparagine]] |
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| − | |[[Image:29S_2.png|thumb|150px|Amino acid Serine]] |
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| − | |[[Image:N29S.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs121907979 |
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| − | |Leu -> Arg |
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| − | |[[Image:L39.png|thumb|150px|Amino acid Leucine]] |
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| − | |[[Image:39R.png|thumb|150px|Amino acid Arginine]] |
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| − | |[[Image:L39R.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs61731240 |
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| − | |His -> Asp |
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| − | |[[Image:H179.png|thumb|150px|Amino acid Histidine]] |
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| − | |[[Image:179D.png|thumb|150px|Amino acid Aspartate]] |
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| − | |[[Image:H179D.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs121907974 |
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| − | |Phe -> Ser |
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| − | |[[Image:F211.png|thumb|150px|Amino acid Phenylalanine]] |
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| − | |[[Image:211S.png|thumb|150px|Amino acid Serine]] |
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| − | |[[Image:F211S.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs61747114 |
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| − | |Leu -> Phe |
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| − | |[[Image:L248.png|thumb|150px|Amino acid Leucine]] |
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| − | |[[Image:248W.png|thumb|150px|Amino acid Phenylalanine]] |
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| − | |[[Image:L248W.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs1054374 |
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| − | |Ser -> Ile |
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| − | |[[Image:S293.png|thumb|150px|Amino acid Serine]] |
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| − | |[[Image:293I.png|thumb|150px|Amino acid Isoleucine]] |
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| − | |[[Image:S293I.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs121907967 |
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| − | |Trp -> TER |
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| − | |[[Image:W329.png|thumb|150px|Amino acid Tryptophan]] |
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| − | | |
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| − | |[[Image:prot_ter.png|thumb|150px|Visualization of the mutated protein]] |
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| − | |- |
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| − | |rs1800430 |
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| − | |Asn -> Asp |
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| − | |[[Image:N399.png|thumb|150px|Amino acid Asparagine]] |
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| − | |[[Image:399D.png|thumb|150px|Amino acid Aspartic acid]] |
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| − | |[[Image:N399D.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs121907982 |
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| − | |Ile -> Val |
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| − | |[[Image:I436.png|thumb|150px|Amino acid Isoleucine]] |
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| − | |[[Image:436V.png|thumb|150px|Amino acid Valin]] |
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| − | |[[Image:I436V.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |rs121907968 |
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| − | |Trp -> Arg |
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| − | |[[Image:W485.png|thumb|150px|Amino acid Tryptophan]] |
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| − | |[[Image:485R.png|thumb|150px|Amino acid Arginine]] |
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| − | |[[Image:W485R.png|thumb|150px|Picture which visualize the mutation]] |
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| − | |- |
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| − | |} |
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| − | [[http://i12r-studfilesrv.informatik.tu-muenchen.de/wiki/index.php/Sequence-based_mutation_analysis_HEXA#Summary_page Back to Sequence-based mutation analysis]] |
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| − | === Substitutions Matrices === |
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| − | {| border="1" style="text-align:center; border-spacing:0;" |
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| − | |rowspan="2" | SNP-id |
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| − | |rowspan="2" | mutation codon |
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| − | |colspan="3" | PAM 1 |
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| − | |colspan="3" | Pam 250 |
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| − | |colspan="3" | BLOSOUM 62 |
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| − | |- |
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| − | |value aa |
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| − | |most frequent substitution |
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| − | |rarest substitution |
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| − | |value aa |
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| − | |most frequent substitution |
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| − | |rarest substitution |
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| − | |value aa |
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| − | |most frequent substitution |
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| − | |rarest substitution |
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| − | |- |
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| − | |rs4777505 |
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| − | |Asn -> Ser |
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| − | |20 |
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| − | |36 (Asp) |
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| − | |0 (Cys, Met) |
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| − | |5 |
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| − | |7 (Asp) |
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| − | |2 (Cys, Leu, Phe, Trp) |
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| − | |1 |
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| − | |1 (Asp, His, Ser) |
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| − | | -4 (Trp) |
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| − | |- |
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| − | |rs121907979 |
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| − | |Leu -> Arg |
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| − | |1 |
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| − | |22 (Ile) |
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| − | |0 (Asp, Cys) |
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| − | |4 |
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| − | |20 (Met) |
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| − | |2 (Cys) |
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| − | | -2 |
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| − | |0 (Phe) |
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| − | | -4 (Asp, Gly) |
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| − | |- |
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| − | |rs61731240 |
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| − | |His -> Asp |
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| − | |3 |
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| − | |20 (Gln) |
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| − | |0 (Ile, Met) |
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| − | |4 |
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| − | |7 (Gln) |
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| − | |2 (Ala, Cys, Gly, Ile, Leu, Met, Phe, Thr, Trp, Val) |
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| − | | -1 |
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| − | |2 (Tyr) |
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| − | | -3 (Cys, Ile, Leu, Val) |
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| − | |- |
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| − | |rs121907974 |
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| − | |Phe -> Ser |
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| − | |2 |
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| − | |28 (Tyr) |
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| − | |0 (Asp, Cys, Glu, Lys, Pro, Val) |
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| − | |2 |
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| − | |20 (Tyr) |
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| − | |1 (Arg, Asp, Cys, Gln, Glu, Gly, Lys, Pro) |
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| − | | -2 |
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| − | |3 (Tyr) |
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| − | | -4 (Pro) |
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| − | |- |
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| − | |rs61747114 |
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| − | |Leu -> Phe |
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| − | |13 |
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| − | |45 (Met) |
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| − | |0 (Asp, Cys) |
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| − | |13 |
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| − | |20 (Met) |
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| − | |2 (Cys) |
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| − | |0 |
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| − | |2 (Ile, Met) |
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| − | | -4 (Asp, Gly) |
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| − | |- |
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| − | |rs1054374 |
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| − | |Ser -> Ile |
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| − | |2 |
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| − | |38 (Thr) |
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| − | |1 (Leu) |
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| − | |5 |
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| − | |9 (Ala, Gly, Pro, Thr) |
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| − | |3 (Phe) |
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| − | | -2 |
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| − | |1 (Ala, Asn, Thr) |
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| − | | -3 (Trp) |
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| − | |- |
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| − | |rs121907967 |
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| − | |Trp -> TER |
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| − | |X |
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| − | |2 (Arg) |
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| − | |0 (all, except Arg, Phe, Ser, Tyr) |
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| − | |X |
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| − | |2 (Arg) |
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| − | |0 (all, except Arg, His, Leu, Phe, Ser, Tyr) |
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| − | |X |
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| − | |2 (Tyr) |
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| − | | -4 (Asn, Asp, Pro) |
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| − | |- |
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| − | |rs1800430 |
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| − | |Asn -> Asp |
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| − | |36 |
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| − | |36 (Asp) |
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| − | |0 (Cys, Met) |
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| − | |7 |
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| − | |7 (Asp) |
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| − | |2 (Cys, Leu, Phe, Trp) |
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| − | |1 |
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| − | |1 (Asp, His, Ser) |
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| − | | -4 (Trp) |
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| − | |- |
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| − | |rs121907982 |
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| − | |Ile -> Val |
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| − | |33 |
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| − | |33 (Val) |
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| − | |0 (Gly, Pro, Trp) |
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| − | |9 |
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| − | |9 (Val) |
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| − | |1 (Trp) |
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| − | |3 |
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| − | |3 (Val) |
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| − | | -4 (Gly) |
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| − | |- |
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| − | |rs121907968 |
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| − | |Trp -> Arg |
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| − | |2 |
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| − | |2 (Arg) |
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| − | |0 (all, except Arg, Phe, Ser, Tyr) |
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| − | |2 |
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| − | |2 (Arg) |
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| − | |0 (all, except Arg, His, Leu, Phe, Ser, Tyr) |
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| − | | -3 |
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| − | |2 (Tyr) |
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| − | | -4 (Asn, Asp, Pro) |
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| − | |- |
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| − | |} |
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| − | |||
| − | [[http://i12r-studfilesrv.informatik.tu-muenchen.de/wiki/index.php/Sequence-based_mutation_analysis_HEXA#Summary_page Back to Sequence-based mutation analysis]] |
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