Difference between revisions of "Glucocerebrosidase homology modelling"

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(Homologous Structures)
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{| border="1" style="text-align:center; border-spacing:0;"
 
{| border="1" style="text-align:center; border-spacing:0;"
 
|-
 
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|colspan="3" |''' > 60% sequence identity '''
+
|colspan="5" |''' > 60% sequence identity '''
 
|-
 
|-
| '''PDB-ID''' || '''name''' || '''identity'''
+
| '''PDB-ID''' || '''name''' || '''identity''' || organism || template
 
|-
 
|-
| 2nt0 || acid beta-glucosidase with pharmacological chaperone || 99%
+
| 2nt0 || Glucosylceramidase || Homo Sapiens || 99% ||
 
|-
 
|-
 
|colspan="3" |''' > 40% sequence identity '''
 
|colspan="3" |''' > 40% sequence identity '''
 
|-
 
|-
| '''PDB-ID''' || '''name''' || '''identity'''
+
| '''PDB-ID''' || '''name''' || '''identity''' ||
 
|-
 
|-
|colspan="3" |''' > 0% sequence identity'''
+
|colspan="3" |''' > 0% sequence identity'''
 
|-
 
|-
| '''PDB-ID''' || '''name''' || '''identity'''
+
| '''PDB-ID''' || '''name''' || '''identity''' ||
 
|-
 
|-
| 2wnw || Salmonella enterica serovar typhimurium virulence factor SrfJ || 29%
+
| 2wnw || SrfJ || Salmonella enterica subsp. enterica ||29% || x
 
|-
 
|-
| 3clw || conserved exported protein from Bacteroides fragilis || 14%
+
| 3clw || conserved exported protein|| Bacteroides fragilis || 13% ||
 
|-
 
|-
  +
| 3kl0 || Glucuronoxylan Xylanohydrolase || Bacillus subtilis || 18% || x
| 1nof || xylanase || 18%
 
 
|-
 
|-
  +
| 1nof || xylanase || Erwinia chrysanthemi || 18% ||
| 3kl0 || Glucuronoxylan Xylanohydrolase || 20%
 
 
|-
 
|-
| 3qw9 || betaglycan zona pellucida (ZP)-C domain || 15%
+
|| 2e4t || Endoglucanase || Clostridium thermocellum || 11% || x
 
|-
 
|-
  +
| 3ii1 ||Cellulase || Uncultured bacterium || 15% ||
| 2vrq || complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase || 14%
 
 
|-
 
|-
  +
| 1qw9 || Arabinosidase || Geobacillus stearothermophilus || 13% ||
| 1uhv || beta-D-xylosidase from Thermoanaerobacterium saccharolyticum || 13%
 
 
|-
 
|-
| 2c7f || family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum || 15%
+
| 1ik2 || Endoglucanase || Clostridium acetobutylicum || 12 %
 
|-
 
|-
  +
| 2c7f ||alpha-L-Arabinofuranosidase || Clostridium thermocellum || 16% ||
| 3ii1 || bifunctional glucanase-xylanase CelM2 || 15%
 
 
|}
 
|}
   

Revision as of 18:12, 7 June 2011

Homologous Structures

The 10 best results of the sequence search with HHSearch are listed in the table below.

> 60% sequence identity
PDB-ID name identity organism template
2nt0 Glucosylceramidase Homo Sapiens 99%
> 40% sequence identity
PDB-ID name identity
> 0% sequence identity
PDB-ID name identity
2wnw SrfJ Salmonella enterica subsp. enterica 29% x
3clw conserved exported protein Bacteroides fragilis 13%
3kl0 Glucuronoxylan Xylanohydrolase Bacillus subtilis 18% x
1nof xylanase Erwinia chrysanthemi 18%
2e4t Endoglucanase Clostridium thermocellum 11% x
3ii1 Cellulase Uncultured bacterium 15%
1qw9 Arabinosidase Geobacillus stearothermophilus 13%
1ik2 Endoglucanase Clostridium acetobutylicum 12 %
2c7f alpha-L-Arabinofuranosidase Clostridium thermocellum 16%

Calculation of Models

MODELLER

iTasser

SWISS-MODEL

SWISS-MODEL workspace was published by Arnold et al. in 2005. <ref> Arnold K., Bordoli L., Kopp J., and Schwede T. (2006). The SWISS-MODEL Workspace: A web-based environment for protein structure homology modelling. Bioinformatics, 22,195-201.</ref>

Usage - Automated Mode

Usage - Alignment Mode

References

<references />