Difference between revisions of "Structure-based mutation analysis TSD"

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(Dataset)
(Mutations)
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As the week before only disease causing SNPs were assigned to us some mutations had to be replaced. Additionally the reference pdb stricture limited the possibilities as only the second domain was retained fpr the following analzsis. Thus a almost new set of SNPs was chosen:
 
As the week before only disease causing SNPs were assigned to us some mutations had to be replaced. Additionally the reference pdb stricture limited the possibilities as only the second domain was retained fpr the following analzsis. Thus a almost new set of SNPs was chosen:
   
P183L, R178H, R178C, D207E, S293I, F434L, L451V, E482, L484Q, E506D
+
R178H, R178C, P183L, D207E, S293I, F434L, L451V, E482K, L484Q, E506D
   
 
= Structure preparation =
 
= Structure preparation =

Revision as of 14:51, 21 June 2012

No citations, I don't read THAT many books :P

The journal of this task can be found here here.

Mutations

As the week before only disease causing SNPs were assigned to us some mutations had to be replaced. Additionally the reference pdb stricture limited the possibilities as only the second domain was retained fpr the following analzsis. Thus a almost new set of SNPs was chosen:

R178H, R178C, P183L, D207E, S293I, F434L, L451V, E482K, L484Q, E506D

Structure preparation