Difference between revisions of "Structure-based mutation analysis (PKU)"
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== Finding the right structure == |
== Finding the right structure == |
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As proposed we searched the [http://www.uniprot.org/uniprot/P00439 UNIProt entry] for our protein and then selected the entry with the highest resolution and the lowest r-Value. In our case this is [http://www.ebi.ac.uk/pdbe-srv/view/entry/1J8U 1J8U] which is the protein in a complex with its cosubstrate [http://en.wikipedia.org/wiki/Tetrahydrobiopterin BH4]. |
As proposed we searched the [http://www.uniprot.org/uniprot/P00439 UNIProt entry] for our protein and then selected the entry with the highest resolution and the lowest r-Value. In our case this is [http://www.ebi.ac.uk/pdbe-srv/view/entry/1J8U 1J8U] which is the protein in a complex with its cosubstrate [http://en.wikipedia.org/wiki/Tetrahydrobiopterin BH4]. |
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| + | IN the following we will only use this structure, if you like to have a look at all the possibilities, or try what we did on another similar example feel free to browse [[Structures for P00439 in PDB|all our results]] |
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Revision as of 13:39, 18 June 2012
short task description
Finding the right structure
As proposed we searched the UNIProt entry for our protein and then selected the entry with the highest resolution and the lowest r-Value. In our case this is 1J8U which is the protein in a complex with its cosubstrate BH4. IN the following we will only use this structure, if you like to have a look at all the possibilities, or try what we did on another similar example feel free to browse all our results
