Difference between revisions of "Predicting the Effect of SNPs (PKU)"

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(Short Introduction)
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==Short Introduction==
 
==Short Introduction==
   
This week's task builds on the data gathered [[Researching_SNPs_(PKU)|last week]]. We blindly choose 5 disease causing and 5 harmless SNPs and will try to predict their effect from the sequence change alone. You may find a detailed task description [[Task_6_-_Sequence-based_mutation_analysis|at the usual place]].
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This week's task builds on the data gathered [[Researching_SNPs_(PKU)|last week]]. We blindly choose 5 disease causing and 5 harmless SNPs and will try to predict their effect from the sequence change alone. You may find a detailed task description [[Task_6_-_Sequence-based_mutation_analysis|at the usual place]] and consult our [[PKU journal Task6|task journal]].
 
   
 
== Our dataset ==
 
== Our dataset ==

Revision as of 12:43, 13 June 2012

Short Introduction

This week's task builds on the data gathered last week. We blindly choose 5 disease causing and 5 harmless SNPs and will try to predict their effect from the sequence change alone. You may find a detailed task description at the usual place and consult our task journal.

Our dataset

we propose the following dataset:

  • GLU76GLY
  • SER87ARG
  • GLN172HIS
  • ARG158GLN
  • ARG243GLN
  • LEU255SER
  • MET276VAL
  • ALA322GLY
  • GLY337VAL
  • ARG408TRP

You could check them, if you like.. I put them together 5 minutes ago and already forgot, which are which. ;-)

Prediction Methods

SIFT

PolyPhen2

SNAP