Difference between revisions of "Sequence-based mutation analysis HEXA"
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Revision as of 17:03, 23 June 2011
Mutations
| SNP-id | codon number | mutation codon | mutation triplet |
| rs4777505 | 29 | Asn -> Ser | AAC -> AGC |
| rs121907979 | 39 | Leu -> Arg | CTT -> CGT |
| rs61731240 | 179 | His -> Asp | CAT -> GAT |
| rs121907974 | 211 | Phe -> Ser | TTC -> TCC |
| rs61747114 | 248 | Leu -> Phe | CTT -> TTT |
| rs1054374 | 293 | Ser -> Ile | AGT -> ATT |
| rs121907967 | 329 | Trp -> TER | TGG -> TAG |
| rs1800430 | 399 | Asn -> Asp | AAC -> GAC |
| rs121907982 | 436 | Ile -> Val | ATA -> GTA |
| rs121907968 | 485 | Trp -> Arg | gTGG -> CGG |
Analysis of the mutations
We created for each mutation an extra page. The summary of the analysis can be seen in the Summary Section.
Summary page
| method | mutations | |||||||||
| Asn -> Ser (rs4777505) | Leu -> Arg (rs121907979) | His -> Asp (rs61731240) | Phe -> Ser (rs121907974) | Leu -> Phe (rs61747114) | Ser -> Ile (rs1054374) | Trp -> TER (rs121907967) | Asn -> Asp (rs1800430) | Ile -> Val (rs121907982) | Trp -> Arg (rs121907968) | |
| pysiochemical properitites | neutral | non-neutral | non-neutral | non-neutral | neutral | non-neutral | non-neutral | neutral | neutral | non-neutral |
| visuale analysis | todo | non-neutral | non-neutral | non-neutral | todo | neutral | non-neutral | todo | neutral | non-neutral |
| PAM1 | neutral | non-neutral | non-neutral | non-neutral | no statement | non-neutral | no information | neutral | neutral | neutral |
| PAM250 | neutral | non-neutral | no statement | non-neutral | no statement | no statement | no information | neutral | neutral | neutral |
| BLOSUM62 | neutral | no statement | no statement | non-neutral | neutral | non-neutral | no information | neutral | neutral | non-neutral |
| multiple alignment | neutral | neutral | non-neutral | non-neutral | non-neutral | neutral | neutral | neutral | neutral | non-neutral |
| analysis with Jpred | non-neutral | non-neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral | neutral |
| analysis with PsiPred | non-neutral | non-neutral | neutral | neutral | neutral | neutral | neutral | non-neutral | neutral | neutral |
| analysis with real structure | non-neutral | no statement | neutral | neutral | non-neutral | neutral | non-neutral | no statement | non-neutral | non-neutral |
| SNAP Prediction | neutral | non-neutral | non-neutral | non-neutral | neutral | neutral | no information | neutral | neutral | non-neutral |
| SIFT Prediction | neutral | non-neutral | non-neutral | non-neutral | neutral | neutral | no information | neutral | neutral | non-neutral |
| PolyPhen2 Prediction | neutral | non-neutral | non-neutral | non-neutral | neutral | neutral | no information | neutral | neutral | non-neutral |
