Difference between revisions of "Task 8 (MSUD)"

Revision as of 14:44, 27 June 2013

The following table shows the prediction of mutation effects by SIFT. 6 out of 10 mutations are predicted to affect protein function.

mutation	prediction	score	median sequence conservation	sequences represented at position
P38H	tolerated	0.16	3.16	17
M82L	tolerated	0.56	3.03	43
T151M	tolerated	0.05	3.03	46
A222T	affect protein function	0.04	3.03	46
C264W	affect protein function	0.00	3.03	46
R265W	affect protein function	0.00	3.03	46
R314Q	affect protein function	0.01	3.03	46
R346H	affect protein function	0.00	3.03	46
I361V	tolerated	0.12	3.03	46
Y413H	affect protein function	0.00	3.03	46

@@ Line 4: / Line 4: @@
 === SIFT ===
+The following table shows the prediction of mutation effects by SIFT. 6 out of 10 mutations are predicted to affect protein function.
+{| class='wikitable' border='1' style='width:700px'
+! mutation !! prediction !! score !! median sequence conservation !! sequences represented at position
+|-
+| P38H || tolerated || 0.16 || 3.16 || 17
+|-
+| M82L || tolerated || 0.56 || 3.03 || 43
+|-
+| T151M || tolerated || 0.05 || 3.03 || 46
+|- style="background-color: #FFBBBB;"
+| A222T || affect protein function || 0.04 || 3.03 || 46
+|- style="background-color: #FFBBBB;"
+| C264W || affect protein function || 0.00 || 3.03 || 46
+|- style="background-color: #FFBBBB;"
+| R265W || affect protein function || 0.00 || 3.03 || 46
+|- style="background-color: #FFBBBB;"
+| R314Q || affect protein function || 0.01 || 3.03 || 46
+|- style="background-color: #FFBBBB;"
+| R346H || affect protein function || 0.00 || 3.03 || 46
+|-
+| I361V || tolerated || 0.12 || 3.03 || 46
+|- style="background-color: #FFBBBB;"
+| Y413H || affect protein function || 0.00 || 3.03 || 46
+|}
 === Polyphen2 ===