Difference between revisions of "BCKDHA"
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==References== |
==References== |
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+ | [http://www.ncbi.nlm.nih.gov/gene/593 branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA)] |
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+ | [http://www.ncbi.nlm.nih.gov/gene/594 branched chain keto acid dehydrogenase E1, beta polypeptide (BCKDHB)] |
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+ | [http://www.ncbi.nlm.nih.gov/gene/1629 dihydrolipoamide branched chain transacylase E2 (DBT)] |
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+ | [http://www.ncbi.nlm.nih.gov/gene/1738 dihydrolipoamide dehydrogenase (DLD)] |
Revision as of 13:51, 28 April 2013
The gene BCKDHA encodes the E1 subunit of the human branched-chain alpha-keto acid dehydrogenase complex (BCKDC). It locates on chromosome 19.
Contents
Reference sequence
Genomic sequence
>gi|260593636|ref|NG_013004.1| Homo sapiens branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA), RefSeqGene on chromosome 19 GGCAGCTGGTAGGGAGGAGCTGGGGGGGTGATTTTGACAAACTGGGCACCACTCAGAGGTTCAGCAGGGC CCAATTACCAGGCAGCCCAATCTTCGGCCTCAGGATCACTTCGAGTGTGGCCTTGTTGAAAATCTCTTTG CTGACCTTCACCTCGGCCGGCCCGTACACACCCGCCAGGACAGAGGTGTCACCTGAGGAGACAGCAGGGA GGGCCTCACTCACAGCTTCCCTGCTCCTGGGGCCCCATTTGTGGCACTGAGCCTGACGGCCAGGGCTCCC CACGTCACCCCCGCCATTTGTTGGTACTGATTCTTTGAGCACTCACTTCATTTCTCTCATTTGTAAAATG GGGAAAATAGCAGTCCCTCCCCGCTAGCGTCTTGTGAGGATCAAAGGACACAATTCACAGAAAACACTTA GAACACTGCGGGGCTCACGCTGAATGTGCAACAGACTTTAGCTGTATTAGTAACATTCGTCCATTCAGGC ATTCAGGCAGGGTCTCACTCTCATTGCCCAGGCTGGAGTGCAGTGGTGCCATCACGGCTCATTGCAGCCT TGACCTTCTGGGCTCAAGTGATCCTCCCGCCTCAGCCTCCCAAGTAGCTGGAACTACAGGCATGTGCCAC CATGCCTGACTAATTTTTATATTTTTAGTAGAGAGGGGATTTTGCCATGTTGCTCAGGCGGGTTTCGAAC TCCTGGGCAACTGTAATCCCAAGGTGCTAGGATTACAGGCGTGAGCTACCACGCCTGGCCCTGATATTAG TAATTTTTTTTTTTTTAATGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGTAATCTC GGCTCACCGCAACCTCTGCCTCCCGGGTTCAAGCAGTTCTCCTGCCTCAGCCTACTGAGTAGCTGGGATT ACAGGCGCGCGCCACCACACCTGGCTAATTTTTTTATTTTTAGTAGAGACTGGGTTTCACCATGTTGGTC AGGCTGGTCTCGAACTTCCTGACCTCATGATCTGCCCGCCTCCCAAAGCGCTGGGATTACAGGCGTGAGC CACTGTGCCCGGCTGGTATTAGTAACTTTTAACAGGAAGTTCTTCCTGAAAGCTAACCATCCTCCCTCTT ACTGCAGCTGCTCTCAACTTCTCTTTCCAAAGCTTCCCCAGCCCAGCTCTTCCCTTAGGCACTGGCCCCC AAATTTTGCATCAGTCTGGACACCTGAGAAAGGGATAATATCTGGAATGAATCCTGATTCCTTATTTCCC CAGAAGCTATGAACGGGGTACAGGAGGTAAAACCTAAGAAATAAACAGCCTGGCTTCTAGTACTGTCTGC TGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCATCCTAG TCAACATGGTGAAACCCTATCTCTACTAAAGATACAAAAATTAGCTGGGCATAGTGGTGGGTGCCTGTAA TCTCAGCTACTTGGGAGGCCGACGCAGGAGAATTGCTGGAACCGGGGAGGCGGAGGTTGCAGTGAGCCGA GATCACACCATTGCACTCCAGCCTGGACAATAACAGCAAGGCTTAGTCTCAATAAAAAAAAAAAAATACA TTTTAGGCCAGGCATGGTGGCTCACACCTGTAATCCCAGCACTATGGAGGCCCAGGTGGGAGGACTGCTT GAGGCCAGGAGTTTGAGACCAGCCTGAGCAGCATAGGAAGACTCCTGTCTCTATTTTCTTTTTTGGGACA GAGTTTCCCTCTGTCACCCAGGAGGCTGGAGTGCAGTGGCGCAATCTCAGTTCACTGCAACCTCCGCCTC CCAGGCTCAAGTGATTCTTGTACCTCAACCTCCAGAGTAGCTGAGATTACAGGTGCGTGCTACCACATCC GACTAATTTTTGTATTTTTAGTAGAGATGGGTTTTCACCATGTTGGCCAATCTGGTCTCAGAACTCCTGA CCTCAACCAAGCGAGGTGGCTCACGCCTGTAATCCCAGCACTGTGGGAGGCTGAGGCAGGTGGATCACAG GGTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAACCACAAAAATTAG CCGGGCGCGGTGGCACGCACCTGTGGTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATTGCTTGAACCC GGGAGGTGGAGGGTGCAGTGAGCCACGATCACTTCACTGCACTCCAGCCTGGGCGACAGGGCGAGACTCC ATCTCAAAAAAAAAAAAAGAAAAAAAAAAAAAGAACTCCTGACCTCAGAGGCCTCCCAAAGTGCTGGGAT TACCGCTGTGAGCAACTGCACCCGGCCTCTTCTTAATTCTTACGTTCGAAGAAACTTTAGGTATCTCAAT TCAGCATAAGCGCTAAGCCTGAGGGAGGGCCTGGGAAGGTCCTTGGTTAAGGCCGTATTTCCTGGGAAGC CCAATTTGCCCTTACACGGAAGGTATGCTTAGTTCCAGGAGAAACTGCCCTGAGGACTGGAGAAGTTACC AAAACAGAACTTGCCTCTGGCTCCAGATGAACTGCCTGTGTTTTGCCCGAGCACAAGAGTCTCTCCCCTC TCACCTTCTTGAAGACGTGGCTCCAGCAATTCTCTCCCCTGTTGACCCCACAACAATCTACAACTCCTGC CCCACTTATCTGATCCTCTTACAGCAGAACTCCTGAACAGCTGCCTCTTCTTCCTTTTCTGTGACCCCAC CACTCCATTGCGGCAGCTCAACATCGTCACCACTGACCTCCAAATGATCAACCCTCCCATGACCCGGCTG TCAGTAAGGCTGAAACAGCTGGTCAGCCCTCACATCTCAGACATGCTCTTTTCTTGGCCCCAGGTCACCA CCATCTCCTGGTTTCCCCCTAACTCTCTGGGCGTTCCTTCTGAGTCTCCTTTGCTAGCTTGTCACATGTC TCTGACTGCTCAAGTTGGAAGGCCTAGGGCTTGGTCCTGGGACCTCTTCTCTTTTCCATCTACACTCACT TCGTTCAGGCAATAGCCTGAAATACCATCTATATAGCCAGAGAGTTCCAAATTGCCTATGTCCAGCTTGG GTCTCTCTTCTGATTTCCAGACTTGTACAGATCTGGGCAGAAACCTTAGTTATGCCTGAATCTTTTTCCT CGCACTCAAACCAAACTATACGTAAGTTTTGTCCGTATTACTTTCAAACTACATCCAGAATCTCATCACC TCCACTACTCCTGCTCTGGCTGGAGCCACCATCACCTCCCTGTTTTCCCCCATACTCCCCACAATCAACA CAGCAGCCAAATTTTGTTAAAATGTATTGGGGCTGGGCGTGGTGGCTCATACCTGTATGAGCACTTTGGG AGGAGGATTGCTTGAGCCCAGGAGTTCAAGACCAACCTGGGTGACATCGTGAGACGCTGTCTCAATTTTT TTTTTTTTTGAGACAGAGTCTTGCTTTGTCGCTCACGCTGGAGTACAATGGCACGATCTCGGCCCACTGC AACTTCTGCCTCCCAGGTTCAAGTGATTGTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCGCCC GCCACCATGCCTGGCTAGTTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCT CGAACTCCTGACCTCAGGTGAGCCACAGGTCTTGGCCTCCCAAAGTGTGGGGATTACAGGCGTGAGCCAC CGCCCCCGGCCTCCCGTCTCAAACGTTAAAGAGAAATATTCTTGGAGTTAATCTACTTCTGAGAGTTATT TAGCTAGGAAAAGGGGATATTTGCTCTATAGGTAAGACTTGCCCTAATCTTTTTTTTTTTTTTTTTTTTG ACTTGCCCTAATCTTAGGGATATTTACTTGTGTGGAGAGATGCAGTGAGGTAGCGGTGGGGATGTATTTC TCAACCCAGCGCAATGACATTATCTTCAATTTGAGGAGTATTTACGTGGGTGAAAGATCCGCCACAGTCC ACAGTATGCAAATAGACAGGTTTGCTTCAGTCCGGGATGCAAGGACCTAGAGGGTGTGTGTGTGGGGGGT GGGGGTGGGAGGGTGGAGGAGGAATCGAGTTAAGGGGGATATTTACCCTGGCGAGGTGATTTTCCCTATT CTGAAATATCAATTCTTGGGCGGACAGTCTGCCCCTCCTCTCATTCTCAGAGATAGTTACAAAGATGGAA CTATCTTCTCCTTTCTAGTCGTGAGGGAGAGATGTGTGTATCCCTGCGTATTTAGTAGTATTCAATCGGA CAAGAAATCATGCATCAACGCAGGAGTGACATTTACCAGCTGGTATCGTGAGGAGGTGGGCACTCGGTTG CACAGTACACGGTAGTCCCTCTCCAAAAGAAAGACCTGGGTGAAGTTCTTACCTTGCAGGAAGGAAGCAG AGCCATCTGGCCGCGACAGCAGGTTCTGTTCGCAGGCAAAGTGCCGGAGGCTGCAGCCAGGACCCCGAGG GCTGGACCCTGTTCCATTTTCAGCACGGATTTTGGCGTCAGTATGCGTCTCCTCCTCCATCGCGCCGAGC CCACGTGCGGCTGCAGTTGTCACTTCCGCCTGGCAGCGCGCGCCGCAAACAGGCTGCGTAACCAGTGCGC ACGCGCCGGGCTGGGCCATCCTCCTGGGCGTCCGCACGTGGCTTAGCGTTTACCAACAATCTGGCTCCGC CCAGTCCCACCTCCTAACTCTGGCAACGCCATTGGACATTTGGGAACAGAAGGCAGGCCTTGGCATTGAT CCGCTTTACTCTGGGCCCCCGGGCCCTAAATCCCTGAGGCCCTGGTCAGGTTGCCCTCTTCTTTGCCTGT TACAGGAGTAACTACAATGAGGCGATTGGAGAAAATTTTGGGTAGATAGATTTTTTTTTCTCCAAATCTC TGTGCATTCTATCTACCACAGAACGGGAAGAAGATGGTTTTCTTGTCAGATGGTGCTGGAGTTTGCGTCA GGCACATAAAGAGGCAGCCCCGAATCTAGCCTACGTGAGTGCCGGACCGCTGAGTGGTTGTTAGCCAAGA TGGCGGTAGCGATCGCTGCAGCGAGGGTCTGGCGGCTAAACCGTGGTTTGAGCCAGGCTGCCCTCCTGCT GCTGCGGCAGCCTGGGGCTCGGGGACTGGCTAGATCTGTGAGTACCTGGGCCCCAGGCGGTTTTCCCAAA GGGGATTAGGGATGTAAAGGCTATCTTCAGAGTGTGGGGTCCCTGAAGGATATGAAGGAAGGGCTGTCAC AAAAGGGAAAAAGAGTGGGAGACTCCTTGGAGAAGACACCGAAGGGAAGATCTGCCACTTCCTTAGGAGA CGAAAAGAACTTCCACTTCTTTAGGAGAGGAAAAAACCCGTTTGCAACTTCTTTGTGGGCCCTGAGGGAG ACGACTTGAAGAGAGAGATGGGGGTTCCTTATTAGCTGCCACTGGTATTCAGGGGAGGCTCCTTGGAGGA ACAGGGGAAGACCGCAAGACCTTCTCCCTCAGGGTTTGGAGAATGAAACTGACTTTGTAAGGGAGGGACT TTCTTCTGGGCAAAGATCCCTCTTCAAGAAGAAGAAAGAAGAGAACAGGTCCCTGTCACAGGCTGCATAG GGCCTTGTATTTCTTTGCTCCTTTGCCACAATTCTGATTTTAAAATGAATTGTGTAAAAAATTTGTTTGA TTCCTGTGTCTCTTGATCGAATATCAAGACAGAGAATTCGTGTGTTCTGGACACTGTACAGAGGAGACGA TTAATATTTGTTGAATTAATGAGGGGAAAAAAGGAGGGAGAGAGGTACAGACAGGGCACTTTGCCCACAT TTCTTAGAAACACTTGAGAAGGCTTTGTTTCTTGTCAAAAGGGTCACAATCCCTTCAGGTGGATGCTGCT AAGGGCAAGATTACACTGCAAAAAACCTAGGTGGAAGCCTATCTTTAGACGGGGAGAGGCAATGGGTTGC AGAAGAGCTTTGAACTACAGTTGACAGATAGGAGAGTAGTGGTTACATGGGTGGATGCATGTCCTTGCTC TGCCGCTTTCCACTTGTGTAGCCTTGGCCAACGGACTGCACTTCTCTGGATCTATGGAGCTAATTTTCCT CTCTAAAATATTAACAGTGGCCACCTCATAGGGCTGTGAAAAATCAATATGTAAAATGCTAAGGACTGGA CCTGGCACATCCTAAGGGCAATAGGAATGTTGATAGTGAGGGTGGAGGGAAGGGACAGAAACTAACCTTG GAGATGGGGAGAAGAAAGGGGTGACCTTGGGAAGGCCTGGATTGGTGAGGCCCTGGGGAAAAAAATCTGA AAAGATATTGTGAGGTTGAGTCTGATCCTCTGATCCCCAATCCATAAGGAGGGGAAGATGGAATCTGTAG AAAGAAGCTCTGGGTAGGGGAACAAACGGGAGGAGGGTGAAGAAGATGGGCCAGGAGTAGGACGTAGTAG GTATCTAGGAACGGAGTCACTTGAAACAGGTAAATACAGAAGGGCTGCAGGAGCAAGGTGTGGGTAGGGC AGTCTCTTGCCTTTGGGCTGGAGACCTTTTCACTTTTTTTTTTTTTTTTTTTTTTGAGCAGTTCATATCC TCCACAGCTGATCTCAGTCCCAGGGGCCCATTGGCTGGGCAAGTGGGGCAGGAGGTGGGCAGGACTGGGG CAGGCTAGGGAAAGGTCATTTATGGCTGATTAAATCTTTCTCTCCTGTCTCAATCTCTTGATTACCTTTC CTCTTGCTTCCCCTACTTCATTTTTGGTGGGGAGTGGGGAGGGAAGAAGTCCCTACTTTTTATTTATATA TATTTAAATTTGTATTATCTTAAGAGTTATTGTTTTTTCCCCTTTATTTCTCCCACCTGTTCTTTCTCTC TTCTTCTTTCTTTCCTCTCCTTCTCCTCTCCTCTCCTCCCCTCTCCTTTTTCTTTTCTTTTCTTTTTCCC TTTCCTTTCCTTTCCTTTTCTCTTCTCTTTTCTCTCTCTCTTTCTTTCTGTACCTCTCTTTCCTTTTTCT TTTTTTTTCTTTTTTGAGACAGAGTTTCACTCTCTCGCCTAGGCTGGAGTGCAGCAGCATGATCTTGACT TACTGCAATCTCTGCCTGCCGAGTTCAAGCAATTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGATTACAG GCATGCACTATCACGCCTGGCTAATTTTTGTATTTTTGGTAGGGACGAGGTTTCACCATGTTGTCCAGGC TGGTCTCGAACTTCTGGCCTCAAGTTCCGCCTGTCTTGGCCTCCAAAAGCATGAGCCACTGCGCCTAGCC TTTTCTTTTTTTGAGACAAGGTCTCACTCTGTCACCCAGGCTGGAGTGAGTGCAGTGGTGTGATCATGGC TCACTGCAGCCTCAACCTCCTGGGCTCAAGCAATCCCCCCACCTCCACCTCCTAAGTAGCTGGGACCACA GGCACGTGCTACTACGCCTGGCTAATTTTTAATTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTC ACCCAAGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCACTTCCCAGGTTCAAGTGATTCT CCTGCCTCAGCCTCCCAAATAGCTGGGACTACTGGCGTGCGCCACCATACCCAGTTAATTTTTGTATTTT TAGTAGAGATGGGGTTTCACCATGTTGACCAGGCTGGTCTTGAACTCCTGATCTAAGGTGATCTGCCCGC CTCGGCCTCCCAAAGTGCTGGGATTACAGGCATAAGCCACTGTGCCTGGCTGCGCCTGGCTAATTTTTAA ATCTTTGTAGAGATGGGGTTTTGCCATGTTTTCCAGGCTGGTCTTGAACTCCTGGACTCAAGCGATCTTC CTGCCTCAGCCTCCCAAAGTGCAGGATGACAAGCGTGAGCCACCTTGCCTGGCCATATTATTAAATTATC ATGAGTTTAAGTTTAAGTAGCCACAAGTGGGCTGGGTGCGGTGGCTCATGCCTGTAATCCCAGCATTTTG AGAGGCCAAGGTGGGCGGGTTGCCTGAGGCCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCC ATCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTAATGGCGTGTGCCTGTAGTCCCAGCTACTTGGGA GGCTGAGGCAGAAGAATCGCTTGAACCTGGGAGGCGGAGATTGCAGTGAGCCGAGATCGCACCACTATAC CCCAGCCTAGGTGACAGAGCAGCCCTCTGTCTCAAAATAAGATAGCCACAAGTGGTTGGTGGCTGCCACA TTAGATGGTGCAGGGTTTTTGTTTTGTTTTGTTTTTTGTTTTTTCGAGGTGGAGTTTTGCTCTCATTGCC TAGGCTGGAGTGCAATGGCATGATCTTGGCTCACCACAACCTCCTCTTCCTGGGTTCAAGCGATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCACCACCATGCCTGGCTAATTTTGTATTTTTAGT AGAGACAGGGTTTCTCCATGTTGATCAGGCTGGTCTTGAACTCCCGACCTCAGGCGACCCACCCACCTCG GCCTCCCAGAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCTAAGATGATGCAGTTTTATCCAGG TGGAGATGAAGAAATAGTCAGGGAAAGGTTGAGAGGCTGCATATTGTAGACAGATTGGATTACTGGGTTC ACTGGGGAAGATTGGATTAGAAGGAGGAGTGGGGCTGCTTTACTTGTCCCCGACTTCTTGCCCCTGCTCT GCCCACTCCTTCATTGAATACCCTGCTGCCCTGCAGATGTGTTTGCCTGATTTTCACCTCCCTTCCTGTC TCTGTTATCATAGCAGACGTTTTAGTGCTCAGGGAAAGGAGGAGGAAGGAAACTCAGATTGTCAAGGAAT TGTGAGTCAGTTTCTCAGCCACTACCCCAGGCCTGGGCTTGGCTAAGTCATTTCACCTCTCTGACCCTAG CTAGTGGGGTGAATAGAGTCCCTACCCTGTTGGAAGTCAGGAAGCCCCTGGAGCTCGCTCTGTGCTAATT ATCGGTGACTATTTCTGTGACCCAGCTCTTCAGGGGCAGCCTGTCTGGGGGTTCCAGTGCCCTGTGCAGT ATCTCCAAGTGGTAGGTACTCAGTGTATGTATTAGTCCGTTTTCAGGCTGCTAATAAAAACACACCCAAG ACTGGGTAATTTATAAAGAAAAAGAGGCTTAATGGACTCACAGTTCCACATGGCTGGGGAAGCCTCACAA ACATGGCGGAAGGCAAATGAGGAGCAAAGTCACATCTTACATGGTGGCAGGCAGACAGAGTGCTTGCAGG GGAACTCCCCTTTATAAAACCATCAGATCTCGTGAGACTTATTCAGTATAATGAGAACAGCACGTGAAAG ATCCACCCCCATAATTCAATTACCTCCCACTGGCTCCTTCCCACAACATGTGGGAATTATGGGAGCTATA ATTCAAGATGAGATTTGAGTGGGGACAGAGACAAACCATGTCAGTGTGTATTGTGGGATGAATGGAGATG GTCATTACAGTCTTCTAAGTGTATGGGTCCATCTCTTACTTGCTAGTGTGTTAAGAAACCTGGCCTCCTT TTTCACATCTTGAGGCACTGAATGGTTTACAAATCCAACTCTAATTTTTTATTATATTTAATACACCAAT AGTGCAAGGCCTTTATTGGTAGTACTCTCCTATTACAGATGGAGAGACTGAGGCTCAGAGAGGTGAGGTC TGAACTTGGAGCTCTGGACTCCAAAACCCAGTTTCTTTTCATGGTACCAGGCTGCCAGGAGGAGAAAGGA TGGAGCTTAGATTCAAGTCTTGCAACATTCTTCTTAGTCCAGTATTGGCTTATTTTGTTTTATATTTTTT TGAGACGGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCGTGATTTCTGCTCACTGCAACCTCTG CCTCCTGGGTTAAGCGATTGTCCTGCCTCCCCCTCTCGAGTAGCTGGGACTACAGGTGTGTGCCACCGTG TCCGGCTAATTTTTATATTTTTAATAGAGACAGGGTTTTGCCATGTTGGCCAGGCTGGTCTCGAACTCCT GGCCTCAACTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGGTTACAGGCGTGAGCCACCATGTGTGG CCGGGCAGGTGATTTTTCTTGTCTTTCGCCTCTTTCCACTTCAGTCCCCCTGGCCATCTTTCCCTTCCTT GAATGTGCCTCCTCCCACCTGGTGGCCTTTGTAGGTATGAGGTCCTTCAGATGATGGCTGACATGACACT TCCTCAGAGAAGCGTTCCAGACCCCAAACACCAGGTCTCTGTCTGTGAAACAGGGACAGTGATACCTGCC TAATCTGCACGCCTTTCCCTTCTCACGAGATATTCTGGGAAGGGGGACTCAACTCTTTGCTCTGTTTGAG GGCAGAGTGCCTTTGAGCTCAGGAGAGAGTGGGTTTGGGTGGCCTTAGCTACCCTAGATACGGAGGACTT GGAGTTAACTGGCACCATCCACAAAGCCTTGCATGCACTGGACCTGAACAAGTTGCTTAGCCCTTGAGGC GGCGCCTCAGCTACCACCTGTCTTTGATGGAGTTATGATAACAGTGCCTGCCCCGTCTGGATGCCTTATG GGTTCAGTGAGCACATAGGTGTAAATAAAGTGCTTTGAGTGGCACCTCAGCATGTAGTTATTCTCTGATT GACCTATAGCAGCCATGCCAGTCTTCAGGGTCCCAGGGCGCCAGGCTTTCTTCTCTTGCCTTGGAGCCTT GGTTTTTCCCTAGGACTGAAGTGTTCTGACCCCTTGGCTGAACTCCCCCTTCTTTAGGAAGCTTTCCCTG GTGTGCCATCTGATGCTGGTGCTTCCTGGAGGGGTACTATCTGATCCTAGCTGGTGAGGCATTCCTGCCA GAGCTGCGGCAGGTGCTTTCCCCGCCTCTCCACCAGCCTGTGAGGTGGATGCCATCCCCACGAGGGCACG CAGGTTCACAGAGACTGGCTCCTGTCCAAGGCCGCGTGGCTGGAAAGAGACAGAACCAGATTCAAACACC AGCAGTTTAACCCTAGAGACCCTCATCCTACCTCCTATGTGGGTAACCACTATACATCCTGCCTCCTCTG AAATCTCCCGTTTTTTTTTATTTTAAAATTTTATGTGAGTATTTACTTATTTATTTGCTGCTGTTGTTAT TGTTTTGAGACAGAGTCTTGCTCTGTTTTCACCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTGC AACCTCTGCCTCCTCGGCTCAAGCGATTCTCGTGCCTCAGTCTCCCGAGTAGCTGGGACTACAGACATGC ACCACCATGCCTGGCTAATTTTTGTGTCTTTAGTAGAGATGGGGTTTCGCCATATTGGCCAGGCTGGTCT TGAACTCCTGGCTTCGAGTGAACTGCCTGCCCTGGCCTCCCAAAGTATTGAGATTATAAGCATAAGCCAC TGTGCCCGGCCAAAATTTTATTTATTTATTTATTTTTTTGAGATGTAGTCTTGCTCTGTCACCCAGGCTG GAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCTGCCTCCCAGGTTGACGCCATTCTCCTGCCTCAG CCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGA TAGGGTTTCACCTTATTAGCCAGGATGGTCTCGATCTCCCGACCTCATGATCCGCCCGCCTCGGTCTCCC AAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCAGCCTAATTTTATTTATTAATTTATTTGAGATGG AGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTGCAACCTCCACCTCCCAG GTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTATAGGTGCGTGCCACCACGCCTGGCT AATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATCGTGATCAGCCTGACAGGCTGGTCATGAACTCC TGACCTTAAGTGATTCACCTGCCTCAGCCTCCCAAATCTGCTGGGATTACAGGCATGAGCCACCGCACCC AGCCATATTATTTCTGTATTTTCATTTGGCTTACCTGTCAACTTGACACTTTTTTGTTTTTTTAGGCTAG TCAGGTGAAGCAATGTGAGTAAGATCACCTGTCTTGATTATAACTTGTGTGTTCAGTGTTTGTCATTCAT CCCTCCCTGTCTCTAGCCTTCAGTTCAGGGCATGATTTGGAGCAAATGTTCAGTATCTGTTTAACAAGAA CAATCATGAGAAATACTTACTCACTACTTGTGTTTATGAAACATTATGTGCCAGGCACTGGGCTGAGCAA TCCACACAGGTCAACTCGGTTAATCCTCATGACAACCCCTGAGATAAGTACTTATACCACCCTCGGTGTA CACAGGAGGAAACTGAGGCTCAGGGAGTTTTTCTTTAAAAATTTTTTCTTTTTTTTTTCCTTGAGACAGG TCTTACTTTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTTGGCTCACTGCAGCCTCTTGGGCTCCAGC GATCCTCCCACCTCAGCCCCTCAAGTAGTTGGGGAGTACAGGTGTGCACCACCATGCCCAGCTAATTTTT TGTAGGGATGGGGTCTTGCCATGTTATCCAGGCTGGTCTTGAACTCCTGGGCTCAAGCGATCCTCCCTCC TTGGCCTCCCAAAGTGCTGGTATTACAAGTGTGAACCACCACACCTGGCCTTAAATTTTATTTATATATT TATTTTTGTAGAGACGAGGTCTCACTATGTTTCCCAGGCTGGCCTCGAACTCCTGGACTCAAGTGATCCT CTTGCCTCAGCCTCCAGAGTAGCTAGAATTACAGGCGTCTGCCACTGCACTTGGCTCAGGGAGTTTAAGT CACATAATCAGGCAGCGGTCTGCTCAGTTAGAGTCCATGCGCTTAGCCATGGTGCCTTCAAGTGACTCCA CCAGGGTCACCCCAGTACTTCCTGGGCAGACCAGACCATCCAGAGCGGGCAGGTTGTGCTTTCCTGCATG GTGGGAGAGGACGTGGCATGAAGCTTTGTGTAAATCTGTGCAGCCTCTGCCATTGTAAATCACTGGCCAC CGGGACAGACTCCCCCACCCCCTTCCAAAAACTAGAGGAACAGATGGGTGGAGTCGCATCCTTCCTCTGC AGGCATTTGGCCACCCACTCCCATTATGGAGCATTTCCTCAGGACCAGGCACAGCGTGGAGCCCTTTGCA TAGCTCACTGAATTGGGGCAGCAACCCTGGGGCTGGGGACTACCATTATCTCCACCAGCCCAGCAAAGAG GGGAGGAGGGTACAGCCGAGACCCAGCTGCAGTATGTGGAGCACACTGGGGTGCCGTGAAGATAGCTGTC CAGCCTCTAGAGGCTGACAGTCCTGCCCTGACACAGTGGTTTGTTCTCAGACTCTGGCCTCCCCTCTTAG TGCCCGTCTGAAGACTTCAGCCTTCGGTCCTCTTCCATCAGCATGCCGTCTCCCCTGTGCCTCAGTCTCC CTCTCTGGAGTATCTGCTGGGGCCACAGTTTGGTTTTATTGTTCTTTGAGACAGGGTATCACTTTGTTGC CCAGGCTGGAGTGCAATGGTGCAGTCATGGCTCACTGCAGCCTTGACCTCCTGGGCTCAAGCCATCCTCT CACCTCAGCCTCCCGCAACTCCAGTATCTGGACTACATGTAAATGCCACCATTCCCAGCTAATTTTTTTT TTTTTTTTTAGATAGAGTCTCACTCTTGTCACCCAGGCTGGAGTGCAATGGTGCCATCTTGGCTCACTGC AACATCCGCCTCCCAGGTTCAAGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACCT ACCATCATGCACGGCTGTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTTGGCCAGGCTGGTCT TGAACTCCTGACCTCAGGTGATCTGCCTGCCTCGGACTCCCAAAGTGCTGGGATTACAGGCGTGAGCCAC CACGCCCAGCCTTCCTGGCTAATTTAAAAATTTTTCAGAGACGAGGGTTTTGCCTAGGCTGGACTCACTA TGTTGCCTAGGCTGATCTCGAACCACTGGCCTTAAGTGATCCTCCCACCTCAGCCTCCCAAAGTACTGGG ATTACAGGCATGAGCCGCTGCACATCGCCACAGTTTGATTTTAGTATCCACTTTAAGGTGCAGTTAGTTC TTCCCAGCTCCTCTTTTCCCTATCTCATACAGTGTAGTCACTTCCCTTTCTCCCACTTCTCACCTTCCTA GATTTTGTTTTTCTCTCTCTTACCAAGTTTTGAGTATGTAATACGTCCCAGATCGGTGCTGAACCCCTGG TGTGAGTTAACTTAGCAACTTTTCACGTGGTGTTCTGCAGCCTTCTTACAGATAAGGAAATTCAGAGAGG TGAAGTGTTTTTGCAGAGAGCCACACAATGAGCTAAGAAATTAGAACCCAGGGCAGTTGAACTCCAGAGC CAGGGAACTTAACAGCCCATTCATGCATTCACTCAGGAATTCCCTCTTGAGTGCCTGCTGTGAAGGCAAC CTGGACGCTGTCTCTGCCTTCCTGGGATTGTGGTGTGTGTGGGAGACAGACACGAAACAAAGCAATCTTC TAGGTCAGTGTCTGGCTATGCTGGGTACTCAGAAGGGGGAAGCACTGTGCTGCAAGAGGCCGGCTGTTTC CTCCTCACAAGGGGAGGCCTGCAGTGACATTGCCAGGCCTGAATCTGCCCTGCCATTGGGAGTGTAATTT CCTCACGACTACAAATGCAAATAAATACACACACTGAACATGCTACCCCGCTAGAACTGTGGACAGCTTG TTCACTGCAGTTAAAGGAAGACGGAGGGACACATTTGAGCACGCATGTGTGAGATCCAGCTTGTGGCAAA CCCTGCCATTCTTTAACATCTGTGGGAAGTGAAGCCACCATTACTGACCTCGGAGGAATCCCGGGAGTAG TGGGAAGAAAAGTTGCAGATGTTTGAAAATCAGGCTGCAGGGGCAGTTGGGGTGAGGAGCATGGATGTCT AGGAGCCTGAATCTCAGCGTTGGAAGCCCAGTTCTGATGTAATTTTTTTTTTTTTTTTTTTTTTTGAGAC AGGGTCTCACTTTGTCCCCCAGGCTGGAGTGCAGTGGCACAGTCTCAGCTCACTACAGCCTCATCCTTCC AGGTTCAAGCAGTCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGCATGTGTCACCATGCCTTT CTAATGTTTGTATTTTTTTGTGGAGACAGGGTTTCTCACTGTTGCCCAGGCTGGTCTCAAACTCCTGAGC TCATGTGATCCTCCTGCCTTGGCCTTCCAAAGTGCTAGGATTACAGGCGTAAGCCACTGCCCAGCATCCC CACCTTTTTTTTTTTTTTTTTAAATTTGTGGTTTGGTGCAGGTTATTTTACCTCCCCAGGCCTCGGTTTC CTCATCTACTCAAGGGCAATGGCAGATAATCAACCTCACAAATTCCCCGAGGAGTTAGTAGGCTTGTGCC TGCCAGGCTCAGCTGGCTTACAGCAGGTGCTTCATAAGGGGGAGCTATTGCAACGCCTCGGCTGGTTCTA GGCTGCCTAGCTCCAGAGCTAAGAGTCCCAGTGGGTTCATATCCCTTTGAGCATTTATAGGCTTCTCACA GGTCTCCTGGGCTTTCTCAGCCATTCCTCATCTGACCTGAGGAGGTGTGATGTCCTTGCAGGACTCCTCC AGCCCCTCTGAGCTTTTTTTTTTGTTTGAGACAGCATGTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGT GTGATCATGGCTTACTGCAGCCTCCACCTCCTGGGGTCAAGCGATTCTCCCACCTCAGCCTTCCAAGTAG CTGGGACTATAGGTGTATGTTACCATGCTTGAGTAATTTTTAAAATTTTTTGTAGAGATGTGATCTCAGG CTGGTCTTGAACTCCTGGGCTCACCTGGGCTCAAGTAATCCTTGAGCCCAAAGTGTTGGGATTACAGATA TGAGCCACCTTGCCAGGCCCTGAGCTCCTTCTGTCTTCCATGAAGGACACACTATTCCTTGCCTTTTGTC TTTTTTTGTGTGTGTGGCAGGGTCTCTGTTGCCCAGGCTGGGATGTGTTGGTGCAATCTGGGCTTATTGC AACCTCCGCTTCCCGGATTCAAGTGATTCTCCTGCCTCAGCCTCTTGAGTAGCTGGGATTACAGGTGTGC GCAACCACGCCCAGCTAATTTTTGTATTTTTGGTAGACATGGGGTTTCACCATGTTGGCCAGGCTGGTCT CAGCCTCCCGAAGTGTTGGGATTACAGGCATAAGCCACTGTGCCTGGCCACTTTTTGTCTTTTGCATGTT CTATACACCTTGCCGAGAATGTGCTTTCCCTGCCTCCTGGTTATCCCTCAGGTTTCAGCTCTAACATCAC TTCCCCAGGGAAGCCTTACCCTCGCTTTCTTCTGCTATAGGATAATATGAACCACCATCATTGTTACTTG TTTAGTGTCTGCCCTCCCTGCTAGGCAGCAAGGACAGATATCTTGCCTGTCTTAGGTCCCCAGAACCCAG CACAGGGCTTGGAACATGTCAGGTGCTCAAATATTTGTTGAATGAGTCAGTCTGGGCTCGCAGAGGGAGC TGGGACCAGAGTAGAGTGGACACTGAAGCGTATGTAGCAGTTTGCCAGGCGATAGGGAAAGAGACCTTCT TGTAAAGCAAGCAGAGATGAGAGGGAGAAATGAGAATTGCTAAGATTGTTTTGAGCATTTGTTAGGTGGC TTACAGATGCTTTGCTGAACATTTTATTCATGTGATCTTGTTTAAGCCTCTCATTTCCATGAGGGGTTCT CCATTTTTATAGACAAGGAAGGGGACACGTGGAGAGGGGAAGTTACTTTGCCATATCACCCTCTAAGGGA TTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTGTCACCAGGCTAGAGTGCTATGGCGCAATCT CGGCTCACTGCAACCCCCACCTCCCGGGTTCAAGTGATTCTCTTGCCTCAGCCTCCTGAGTAGCTGGGAC TACAGGCATGTGCCACCACATCCGGCTAATTTTTCTATTTTTAGTGGGTACAGGGTTTCGCCATGTTGGC CACATTGATCTCGAACTCCTGACCTCAAGTGAGATTCGCCTGCCTCTGCCTCCTAAAGGCAGTAAGGGAA TTGAACCTAGGCAGTCTGACTCTTAAGAGCTCAAAGACTTAAGCTCTGTCCTGAGTAGCTTCGCTGGTGT ATGGTATAGGGATCAGAAGAGAGCTGGTCTGTATGCCTAGAGGGCATCCTGCAGTGGGCATGTGTGTCTG TGGTCACAGTGGGAGAGAGAGAGGAGGGGGCATCTGTGGCCAGAATGGGGAGGCCTCGAATGCCAGGATG AAGAGTTTGGGCCTATGGTAATGAGAATAGTAATAGCTACCAGTTATTGACTTGCCAGCCACTTGATTGA GTCATTTAACCTCACAACAGTCCTATGGGATAGGTGTTAACTGTTTTCATCCCAGTTTTTCAGATGGGGA AACTGAGACACAGAAGTTGTAGTCAGTTATCCAAAGTGTCGCAGTGAGAAAGTGCTGGAGTTGGGGCTCA GACCCTGTGAGTCAGGCCCCAGAGTTCACTGGGGCCACATGCTCAACCACCATGCCGCCTGCCTGCCGCC GGGGCTGAGCCAGCGGAAACCTGGGTGCTGCTTCTGATGCAGGTGGTCTCCTCTGCTCTCTTCCCCAGCA CCCCCCCAGGCAGCAGCAGCAGTTTTCATCTCTGGATGACAAGCCCCAGTTCCCAGGGGCCTCGGCGGAG TTTATAGATAAGTTGGAATTCATCCAGCCCAACGTCATCTCTGGAATCCCCATCTACCGCGTCATGGACC GGCAAGGCCAGATCATCAACCCCAGCGAGGACCCCCACGTGAGAGGCGGCCTCCCCCACTTCCCGTGCCC CCCACGCCCAGGCCCCTTGCCTGTCTCCTCTCTGGTCCCAACTGCCCCACGTCTATCTGTGCCTCCACCC GCAGCTGCCGAAGGAGAAGGTGCTGAAGCTCTACAAGAGCATGACACTGCTTAACACCATGGACCGCATC CTCTATGAGTCTCAGCGGCAGGTGCGTGGGGACAGGACTAGGGGCGGGGGGCTGGAATTACCTGAGGTCC CCTACCTGTGTTTGGGCCAAAGGAATGGCTCCCAAGGAGGACAGATTCTTTTTTGGGGGGGTTCCATAGA GTTCTGAGGGTTCTCTTGGGACTCTGGAGGAGAAGTGTGAGAGCAGTCCTGCCTTAGGGCAGAAGGATGG ACCTGATCACTAAAAAACACCTACTGTGTGCCTGGCTGGGGGCTCGCCTGTGTGGGGAGAGGGCAGGGAG AAGGCCTGACAGCCCTTCCTCTTGGAAATGCACAGTCCTGAGAAACAGGGTGGGTCCCCAGTGCTTCCTG GAGTGCTCCAGGGGACCGCCCTAGGCCCATGTGAAATGGGCTGTGATCCCCTGATAAATCCTAGTATCAG GGACAAGGATCCAGTCAAGCCAGTGTCAACAAAGAGGGAAGTTATTGACTCCAATGACCATACATCCAGA GGGTCCTGTTTTGGGGCACAGCTAGATCCAGGGGGTCTTCCAGGCAGGAAGTAGAGGGAAGGCGGAAGGC CAGACATGGCACATCCCAGCTATCCCACACCCCCACCTTTATAGAGCTTTCTGGGTAGTCCCACCTAGTG ACATCTGCATACATTTCCTGGGCCACTCCTAGCTGCAGGGGAGACTGAGAAATGTATTAATAATACTTTA GTCCCGGCAGTTGCTGCCTGCGGGAGATTGAGACCTCTGTTAACAGAGGAGGGGAATAGTATACTGGGAA GGCAACCAGGAGCCTCTGCCAGTAGCCCCGAGTCCTGATCCTCAGGGGGCTGGTTGCAGGCTCTTACCCA CGCTAACCTGGACAGTCCTGCCAGGCCCTCAGTACTCAGCACCGCCCACTCACTTGGCACTGGAATGTGC ATTAACTTTTAATTGGCTCCCCACTTAGAAGAAAGCACACATTCATCAGTTTCCCCCACAGCAACGGGAA AGCCAGGCCTGGGAACACATGGAGGAGGGCACCGCCGAGCCGCGAGGAGCTCTGGCCCCGGGGTGTCCCT CAGGGTGCTGGCCAGGCTGCCTTTGTTCCGCTTTACACATGGCCCTGTGTGATCTCATGTCCATCCGTAT GCCAGGGCTGCCCAGAGCCCCAGCCAGACTGCTTGTCAGAGCCCTGCTTGGCTTCTCGCCCTGGATGTCC CACAGCAAACTAATCCTGTCTGAACTTGACCTCGACATCTTCCTCCCAGGCGTGCTCCTTTGCCTCACCT AGTCCGTTTCTCAGTGAAGAGCACCACCATCCACCTGCTTGCCCACACCAGAAACCTCATCTCATCCCTG TCTCCTCCCTCCCCCTTGCTATCCCTTTCTCCCCTCTCATTCCCTCTGTCTGTAGATATTTCTTTTTTTT TTTTTTTTTTACTTTTGAGATGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGG CTCACCGCCTCCCTGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCG CCACCACACCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGTCTGGTCTCG AACTCCCTACCTCAGGTGATCTGCCTGCCTTGGCCTCCCAAAATGGTAGGATTATAGGTGTGAGCCACTG CACCCAGCTGTAGCTACTTCTTTTCTTTTATGTTATTTTTATTTATTTATTTAGAGACGGAGTCCACCTC TGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGA TTCTCCTGCCTTAGCCCCCCAAGTAGCTGGGATTACAGGCGCCCACCACCACACTCGGCTAATTTTTGTA TTTTTAGTAGAGATGGGGTTTCACCACATTGGCCAGGCTAGTCTGGAACTCCTGACCTCAAGTGATCCGC CTGCCTTGGCCTCCCAAAGTACCGGGATTACAGGTGTGAGCCACCGTGCCTAGCCTGTCTGTAGATACAT CTTTAGGAAGTGCTCAGCTGCTCAGCAGCACACTCTGAGACCCAGCCCCATCCTTTCTCTGCTTCACTGT TGTTGGTGAGTTGACCTTCGTGCTCTGCTTGTGGCCTCGTGTTCACAGCATGGCTGCTGCATGTCCAAGC TTCATGGCTGTCTGCAAGGCAGGAAGAAGTAGGGAGTGGGTAGGGCTGGCACCAGCAGCAGTGGTCTCTT CTATCCAGAAAGCAAAAGCAGACTTCCACCAAAATATCTGGCTAAAACTGTGTCCCATGGCCACCTCTGG CTGCAAGGGAGGCCAGGGACCTGAGTGCGTGTCTTTTTGAGGCTCAGGTTAGGGGATTTGGGAGAAGGGA ACTGGGCACTGGTGTGGCCAGCTGACAGGGTCTGCTGCCCCCTAGCACAGCCGACTCAGCTTCCTCAGAC ACATCCACCTGCTCCTCTCCCGCCTCCCTCTGCTACCAAGCTGGGCCTCTGCCCCCTCTCTCCTGGCTTG CTGCAATCAGCCTTGATGACTCCATCCATTTACCTCACTGCAGCCTGAGAGCAATTCTAAAACACAGGTC TGACCACATTGCTCCCTTGAGAAGACTGTCGGCAGGTTACCACTATTCTCAGAGTAAAATCAATGTATCG TTCCCTTTGTTATCTGGGTGCCATCTCCTCTCCCTCCTCATCTTTCCCCACCCCTACCACTGTATGTCCC AGCCCTTCTGGCCTCATGGTCTATCATTCCCTCTGCCTGGAACCCTCCACCCACCCCATCTTTGCGCACT GGTCCTCACCGATGCCCTTCCGTGGTGGAACAGGTGCTTCCTTTGGGCTTCTATCACAGCAACTCGATCC CTCTGGCAGTTCTAAGCAGTCTGGCAGCGTCTTCTTAAAGGCAGGAACCCCAGCATGGCCTGGCCCAGGA CTGGCCTTCAGGAGGACTGTGAATTCATGGAGGTGTTGGAAGCTGGGCAGGATTTGGATGGCTCTCTGTC ATTGCCCAGCATAACCAATTGTGGGACCCCGGTCCCCTCTACACCCCCAGGGCCGGATCTCCTTCTACAT GACCAACTATGGTGAGGAGGGCACGCACGTGGGGAGTGCCGCCGCCCTGGACAACACGGACCTGGTGTTT GGCCAGTACCGGGAGGCAGGTACGTCTGTCCGTGGTTTGGCCCTGTGGTCCCCATTGAAGTGTACACTTT AGTTTTTCTGAGTGTTCTTCCAGGAGCAGCATAGTGCCAGGAAGGTCTAAGGAGCTGGAAGAAGAGCTTT CCAAGCAAGAAAGAGACAAGCCAGGGTTAGGACTCTGGAGGGGGCAGTCTTCCCACTCTGAAGGCCAGAA AGTGTAGTGGCTCAGGGTCTGTGCTCTTAACCCTTTGTTACCAGTTGTCAGGTTTTGGGCAAGTCACTTC CCTTCTCTGAGCCTCAGTTTTCTAATCTCCAGAAGAGGGATTATGACGGTACCTGCATCCAAGGGTCGCT GGGAGGATGCAGTGAAGTCAACGTTCGCTGTGGGTGTGGCCTGTGCAGGAGACCCTGTCTGCCTGGTGCA GTGATCCCCTGGCCCCTCCTCAGGTGCTGTATCCTTCGGGGAGCAGGAGCAGGTGGAAGAACCTTGACAG ACCTGAGTGCGGTGCAAGATTAGAGGGGCCCGGCAAGCCCAGATGAGTGAAAGGAAGGAAGGGTCAAAGA CCAGGAATGAAGAAAATCATTGAGCAGGAATGAGTGCCTGGGAGCGAAGGAGTGAGCCCAGGGAGCAGTG AGTGGGGTCTTCCAGGGAGCTTGTTGGTGTGGGGCCCTGCATGGGGACTACCCTCAGAGTGTCAGCGAGC ACTGATAGGGCCAGGAAGGCATATCTTAACCCTTTGTCTTAGATGCTTGGGGCAAGTTGCTTAACTGCCC TGTGCCTCTGTTTCCTCATTCGTAAGGGGGATGGTAGCCCTTCCCAAGACAGCTGTTGAGGGCAGTCTTG GGGCAGTTGGCAAAGTGCCCTCAGCACAGAGTAAGCGCTCAGGGCCAGGGGTTGGTGTCATGATCGGGGA CTCGCCCTGGGACAGCCCTTCAGCAGGGCCAGACCACGTGGCTGTCCAGAGCCCCCATGGACCAGCATGG CTTGCAGCCTGCTCCTGGACTGTCTACTGCTCACAGCTGGACCAGGCCCTTGGCCCCACATGCTCTAGGA GGGCAAACGCCCTGTGGTGTTTGTCTAAGGTCTAGTGTCATCCGTGCGGAAAAAGATTTCCAGACACCAG GCAGCAAGCTGGGCCCCCGCCAGCTGTGCTGAGCACTGCACCTGTTTTTGCTGAAGGGTTCTCTTGTGAG GGCACCAGGCAGGACCGAGCAAGCCTCATGGGAATCATGGGAGCCGCTGAGCTCTCCACATGGGAGAGCT GGCCGCCTCTGCAAGAATGACTGTCCAGCACTGAGGGTCAGCAGAAGTGTCTGGGCAGCTGCAAATGGGA CTCATGCAGAGGCAGCATGGTGCAGGGTAAGGAGTTGAGTCACATCCACTCTAGACTTCACTTGGCAGGC CACTCACCTTGGTGACGCTGTCTGTCGTCTGTGAAGTGAGAAGAGTGGTGTTCATCATGATAGGTAGTGC CTCCCTGGGCTCTTGACACCAGAGTGCTGTTCTTTTTTTCTTCTCCTTTTTTTTTTTTGAGATGGAATCT CGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCACCTCCTGGGTTCA CGCCATTCTCCTGCTTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCATGCCTGGCTAATTT TTTGTATTTTTAGTAGAGGCGGGTTTCACCATGTTAGCCAGGATGGTCTTGATCTCCTGACCTTGCGATC CGCCCTCCTCCACCTCCTAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGGCCTTTTTTTTTTTT TTTGAGGTGGAGTCTCACTCTGTCGCCCAGGCTGGAGTACGGTGGCGCAGTCTTGGCTCATTGCAACTTC TGCCTTCCAGGTTCAGGTGATTCTCCTGCCTCAGACTCCGGAGTAGCTGGAATTAAAGGCATGCACCACC ATGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCACGTTGGTCAGGCTGGTTTCAAACT CCTGACCTCAAGTGATTCGTTTGCCTTGGCCTCCCAAAGTGCTGGGGATTACAGGCATGAGCCACCGCGC CGGGCCAGCCAAGGTGCTGTTATATGTGCTCTTTAGCCTCGGAGACTGTCATTTCCCCTCACTGCACTGC AGAGCGAGGGCACACCGGGTGAGGTTAGGGCAGGCCCCAGTGGTGTTGCCTCATTGAGGCACCTCCCCCA TCCATGTGAGGCAGGAGAGGCAAGCATTACCATCAACTCTAAAAGCCAGGTAAGAACCTGAGTCAACAAA GGTGAGGTCATGGGCCCAGGCCACATTCTCCTAAGGAGTGGAGCCGAGTCTTTTTATGGCAGTCTGACCC AGAGACAGCTCTCGCTGTTTCCCACCCTTGGCTGTCTTCCCAGGGCTATATGTGGAGTATCAGTGGTGGC ACTGGCAGGGAGTGGCGCCCGGTGAAAAGGAGTGTTAAGAGGAAGCACGTGCCAGGTGTGGTGGCTCACG CCTGTAATCCCAGCACTTCGGGAGGCTGAGGCGGGAGGATTGCTTGAGCCCAGGAGTTTGATACCAGCCT GGGCAACATGGCGAGACCCCCATCTCTAAAAAATTAAAAAATTAGCCAGGCGTGGTGGTGCACACCTGTA GTCCCAGCTACTCAGGAAGCTGAGTGGGAGGATTGCTTGAGCCCAGAGGTTCAAGACTGCAGTGAGCTAT GATTCCACCACCGAACTCCAGTTTGGGTGACAGAGTAAGATCCTGTCTCTGAGACCAACAAGAAAAGAGG TAGCATGTGTCAAGCAAGAGCAGCAGTTCCCACTGGACCTGGAGTTTCCTGGTGCAAATCAGCCTGTGAG TCTGTATTTTCTTTTTTCTTCAAGACGGGGTCTTACTCTGTCACCCAGGTTGAAGTGCAGTGGCATGATC TCGGCTCACTGCAACCTCTGCCTCTTAGGATCAAGTGATCCTCCCACCTCAGCCCCCTGAATAGCTGGGA CCACAGGTGCACGCCACCACACCTGGCTAATTTTTTTTTTGATTTTTGGTAGAGACGGGGTTTCGCTGTG TTGCCCAGGCTGGTCTCAAACTCCTGAGCTCAAGCAGTCCACCTGCCTCACCCTTCCAAAGTGCTGGGAT TACAGGCACGAGCCACTGAGCCTGACAAGTTTGTACTTTTAGCACGTTCCCCTGCCCCTGCCCAGTCCTT CTCACATGGGTGGACCTAGTACCACATTCTGAGAAAGCCTGATTCCAAGGTCCTGTATCAGTCCCTTGGA CCTTCTTTGACCCTCTACAAGACCTTTCTTTCCCTCCTTAACCAGAGCAACTCCTGTTTCTATCTGTTAC ATATGCAGCACAGCCACATCTTGTGTGGATTTGTATTATGTCCATTCAAAAGCATGTGTCAGAAAATACC AGTAAACCTGTATTAAAGTTGGATGTTGAAGTAGTGCTAACCACCCTCAACTCTAACTAAAATATCAACA AGTGGGCTGGGCGTGGTGGCTCACACCTGTAATTGCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCT GAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTCCTGAAAATGCAAAAATTA GCTGGATGTGGTGGCACATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACC CAGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCGCCATTGCATTCTGGGCAACAAGAGCAAAACTCCGTC TCAAAAAAAAAAAAAGAAAGAAAATTAGGTAGATCTAGTGGTGCACACCTGGAATCCCAGCTATCTGGGA GGCTGAGGCATAAGAATTGCTTGAACCTGGAAGGTGGAGGTTGCAGTGAGCTCAGATTGCGCCACTGCAC TCCAGCCTGGGTGGCCAAGCCAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGGTAACTGCTGT GTGTAATGTGATCTCCATTAAATTTGTATCTAAAGAGCGGGTTCTGCGGTAAAGAAAGGATTTGGAAAGC ACTGTACTAGAGAGCTCCCTCTGAATAATGTTCCCGGTCTGAGTGCTTGCAGCATTGATCCACAGCGCTG CCCCTAAAGTGTTGGTGTGAAGGTTGTCCCACTCTTCAGGCGGGGCAAAGAGCTTGTCTGAGGGCAATCA CAAACCCCCTTCTGTCTTCTAACTTCGGAGGAAGGGCCCCCTTAACCTGGAGCGGTTCCCTTTGATGGGG AGGTGGGTGTTCACCAGAGGTTTTGTTTGAAGAAAAGGTTTTACTGCCATACATGGGTTAGAGTACTTCT GTAGTCCAGAAGTTGTAAATTAGTGGTCTATGCTGTTATTTGGTTCATAATGATGATTTTTTTTTTTTTT CGAGACAGGGTCTTGCTTTGTAGCCCAGATTGGAGTGCAGTGGCACGATCTCAGCTGCCTGCAGCCTTGA ACTTCTGGGCTGAAGCAATCCTCTGCCTCAGCCTCCCAAGTAGCTGGAACCACAGGCACACATCACCATG CCTGGCTAATGTTTTGATTTTTTTTTTTTTTTGTAGAAGCGAGGCCTCACCATGTTGCTCAGGCTGGTCT CCAACTCCTGGGCTCAAGCGATCCTCCAACGTCAGCCTCTCAAAGTGCTGGGATTACAGGCATGAACCAC CATGCCTGGCCATAGTAATGATTTATGGTTAGAATATTTCTTAAAGGTAATTGAATTAGTTGAAAGCACT TAAATACCAGACAATATCTCACTAAGAGAAAGAAAGAAAAAGGCTAGATTTCTGCTTTCTTTTGAAAAAT CAGATTGGCCTTGCTGGGCAGAGTCAGTCAGTCTGAACATCAGTCTTCCTCTTAAAACAAGCCTGAGCTT TCCTGTCTGCCTGCCAGCATGCTGCAGGTCACCCACAGGGCTGAACTGTCCCCCTGTACTGCCCACTCGG CTAACCATTGCCTCCTCCCCTCCTAGGTGTGCTGATGTATCGGGACTACCCCCTGGAACTATTCATGGCC CAGTGCTATGGCAACATCAGTGACTTGGGCAAGGGGCGCCAGATGCCTGTCCACTACGGCTGCAAGGAAC GCCACTTCGTCACTATCTCCTCTCCACTGGCCACGCAGATCCCTCAGGGTGAGGATGCATGCCCTGTACC TTGCACATGTGCAGACCAATGTCACACCCCTGTCCAGGCCTCAGCTCTTTTGCCTGCCTTCTGGGTGGAA TTCTGGGTTGGTGACACCACTAGAGCCCTGGTCTGTGCTCCAGACTTCTTCTTCTTATTTTTTTCTTTTT TGAGACGGAGTCTTGCACTGTTGCCCAGGCTAGAGTGCAGTGGTGCTATCGCAGCTCACTGCAGCCTCCT TCTCCCAGCTTCAAGCAATTCTCCTGCCTCAGCCTCCCGATTAGCTGAGACTACAGGTGTGCACCACCAC GCCCAGCTAATTTTTGTATTTTTAATAGAGACAGGGTTTCACCGTGTTGGCCAGGCTGGTCTCAAACTCC CGGCCTCAGGTGATCCACCCGCCTCAGCCTCTCAAAGTGCTGGGATTACAGGCGTTTAAGCCATTGTGCC CAGCCCACTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGTCTGAGACGGGGTTTCACTCTCGTCAG CCAGGTTGGAGTGCAATGGTGCAATCTCGGCTCACTGTAACCTCCACCTCCCAGGCTCAAGTGATTCTCC TGCCTTAGCCTCCTGAGTAGCTGGGATTATGGGCATATGCCATTGTGCTTGGCTAAATTTTTGTATTTTT TGTAGAGATAAGGTTTCACCATTTTGGCCAGGCTGGTCTTGAACCTGAGTTCAAGTGATCTGCCCACCTT GGCCTCTCAAAGTGCTGGGATTACAGATGTGAGCCACTGCACCTGGCCTGTGTTCCAGACTTTGAATGCA CCTCTTGTCTGGGACCCTTCAGAAGAGGGCTCTGTTGCTGTCCCCACCCCATTCAGGGGCCTGAAGCCTG TGTGACCACACTCTGGATTTCCCAACCACATGCCTACTGCATTTGTCTGCTCACAAACATAGCCAACGTG TGCACCAGGTTCCACTGTGCCAATGCTTCACGTTCATCATCTAATAAGGACCCTCATTGTGGCCATGGGG ACAGAGGTTATTATTTGCTCTTGTTCCTGTTTTCAAGAGCAGGATGCCCGTGTTTTGTGTGTGTGTGAGA GACAGCAAGTGAATGGGAAAAAAAAAAGTGCAGGAGCCTGGCCAACATGGCAAAGCCCTGTCCCTACTAA ACATACAAAAATTAGCTTGGCATGGTGGTGCACACCTGTAATCCTAGCTACTCAGGAGGCTGAAGCAGGA GGATTGCTTGAACCTGGGAGGCAGAGTTTGCAGTGAGCTGAGATCGTGCCATTGCACTCTAGCCAAAGTG AGATCCTGTCTCAAAAAAAAAAAAAAGGAAATTGAAGTCAAAGAGGGAAGTCACTCGCTAACGGTCATGT GGCACAGAGGGAGAGGAGCAGGGACTCAAGTCATTGACTGTGTACCTCCAGAGCCTGGGTTCTTGGCCCT GACCTTTGTCTGCCTCAGTCCTCAGAGTCAAGTAAGCTTCCCCAAAGCTTACCGTAGGTGCCCTGAAGTC CCTTCCCTTATAAGAGCTTTTTTGGGAAGCAAACCCACTGGGTGCCAGGCCTGCACCCTCATAGTGTGGA GAACAAGGAATCGGAGCCCCTTCCTGTCCTCCGGGGCCTGTAGCCTGATCTAGGGTTGGTCTGGGCCCTG GCTTCTTTGCCCTAGGGCAGCTGAGATGCATGAGTTTGTGTCTCTCCAGGCCTCAGCACTGTGCCCAGCA CAGCAGGAGGCTCCACACCCCTTAGCTCATAGTGTTCTTTTGTTGAGGAACAAGAAGCAGTTTGAGCCTC TTAGGTGGGAGGTGGGCAGGGAAGCTTTCTCAGAGGAGGGGGCATTTAGGGGGCATTTGAGCTAAAGGTA ATAGGGTTTCCACAAGGCTGGGGCGTGGCCCTAACCTTCCCTCTGGGTCCCTGCTAAGTCACTTCAAATA CACGAAGTTCCTGCCATGTGCCGGTGCCACTCCAAGTGCAGGGAACAAAAGCAACGCAAACCTCAGCCCT CCTGGTGCTGCCATTGTGGTGGGGGAGACGGACAGTAACAGAGATGGAGAGGGAACTCCTGGAGTATATG AGGGTGGGGGTCCTGTAGGGAGCAGCCAAGCCAGCCGGGTGTGGTGCACTGTAGGGGTGGCTGGGGTCCG TCACTGGAGTGACACTGAAGTATGGACCAGAGGATGTGAGGGGGGAGCTGTGTGGTGTCTTGAGGCAGGT GTGAGCCTGGCGTGTTTGAGGAGCTGGGAGGAGCCCAGAGGGGCAGGTGTGGAGTGAGCAGGTGTGGAGT GAGCGGGTGTAGGGTGAGCAGGTGTGGGGTGGTTGGAGGTAAAGTCCAGGAGGTGGTGGGTGGGGGTGCA GATGGTGCAGGTTGGGTGGGGCCTCAAGGCCTTTGCCTGTTGCAGGGATGTCGACTTTTACTCAAAGTGG GACAGGAGCCGTGGGTGGGGAGGAGTCTGCTCTTCCTTGGCCTGGCTCACCTCTTCATGGAATCCGCGGG CTGCCCTGTGGATAAGGGATTGGGCAGTGTGTGAAGGGCTAGTAAGGAGGCTGCTCAGTAACTTGGGCTT GACCAGGGTGGTGCAGAGGAGGAGGTAAGAGGGGTTAGGTTCTGAAGGTGGAGTAGATGTGGAGAATGGC GGGAAGTTTGGCTTGGAGATGATACTGGACTCTTCAGCCTGAGCAGTTGGAAGGGTGGAGTTGCTTTCAG CTGAGCAAGAGGAGACCTGGGTGGGCAGATGCTGGGGGGCATCAGGAGCTGAGGTGTTTCCTTTCCCCTT GAAGCCTGGTGACTGCTGGCCTGAGCCACGCTTGAGCCGTGGGTCATGTGAGTGTGAATGAGTGTGAGTG CATGTGAGTCTCCGCCCCTGCTCACCACCCTCTCATCCCCTGCAGCGGTGGGGGCGGCGTACGCAGCCAA GCGGGCCAATGCCAACAGGGTCGTCATCTGTTACTTCGGCGAGGGGGCAGCCAGTGAGGGGGACGCCCAT GCCGGCTTCAACTTCGCTGCCACACTTGAGTGCCCCATCATCTTCTTCTGCCGGAACAATGGCTACGCCA TCTCCACGCCCACCTCTGAGCAGTATCGCGGCGATGGCATTGGTATGGGCTCTGCTGGCTGCTCCCCACC CCGCTGGGATCATCTCCTTCCCTCCCCAATCCTGCCACCTTCCTGCCACCCCTACCCTCCTTCCTGGTTC TCGTCCTGTGTCCTGTGGCGTCTGGCACTTGGTCAGCCACAGGAGTTGAGGTCCTGAGCACTCAGCCTTG CTCTCTGTCCTCTCCCTGCTCGTCCCCTTGGCCTCGTGCATGTTCCTTATCTCAGCCCTGGCCTGACCTG CCTTCTCTGTGTCCCCACAGCAGCACGAGGCCCCGGGTATGGCATCATGTCAATCCGCGTGGATGGTAAT GATGTGTTTGCCGTATACAACGCCACAAAGGAGGCCCGACGGCGGGCTGTGGCAGAGAACCAGCCCTTCC TCATCGAGGCCATGACCTACAGGTGCCTGCCGCTCCCCCCGTCAGCACCCCCACAGCACTGACAGCCACC GTAGCATCTTCCTCATATCGATCACTGTCTCCAAAACATGGCCTTATCACCTGATGTTGCATCTCCCCCT TGCCTTTATTCCGTTTCCACTCCTCCTTCCCTAGTTCATCCCCCATCCTCCCTCCTGACCCCCACTCCAG GGAGCCCACACTGACCTGGGGCCCCTTGCCCCTGTGCAGGATCGGGCACCACAGCACCAGTGACGACAGT TCAGCGTACCGCTCGGTGGATGAGGTCAATTACTGGGATAAACAGGACCACCCCATCTCCCGGCTGCGGC ACTATCTGCTGAGCCAAGGCTGGTGGGATGAGGAGCAGGAGAAGGCCTGGAGGAAGCAGTCCCGCAGGAA GGTGAGGGTGCCCCGCCCGGGAGGGTGTGCTGGGGGCTGCTGCGGCCTGCAGAGCTTGGGAAGGATTTGT GGAACACCGAACTGGGAGGCTCAGGGATAACCCCAGTGATGTCTCAGATGTGGCCTGTGGAGCCAGGCTG CTGGGGCCATGTGTGTCCTGGCTCTGTGTCCTTGGCATGTTGCCCTCCACTTCCTTGTCTTTGAAAGGGG ATGCTGGTGGTGCCCATTTCAGAAACTGGTTTGAGACTGGGCATGGTGGCTCACACCTGTAATCCCAGCA CTTTGGGAGGCCGAGGTGGCAGATCACTTGAGGTCAGGAGCTTGAGAACAGCCTGGCCAAACATGGTCAA GCCCTGTCTCTACTAAAAATACAAAAATTAGGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTT TGGGAGGCCAAGGCGGACAGATCACCTGAGGTCGGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACC TCGTCTCTAATAAAAATACAAAAATTAGCCGGGCATGGTGCCGGGTGCCTGTAATCCCAGCTACTTGGGA GGCCGAGGCAGGAGAATTGCTTGAACCTGGGAGGTAGAGGTTGCAGTGAGCTGAGATCGTACCATTGCAC TCCAGCCTGGGCAACGAGAGCAAGACTCCATCTCAAAAAAAAAAATTAGCCAGGCGTGGTGGTGCGTGCC TGTAGTCCCAGCTACTCAGGAAGGTGAGGCAGAAGAATCGCTTGAACCCGGGAGGTGGAACTTGCAGTGA TTGGAGATGGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTATCTCTTAAAAAAAAAAAAAAGC TGGTTTGAGGATTAGGTGGCAAACCGTGGTGGAGTGTACATGCCCTGCCCAGAGTCAGTGTGCCACCCTC CCTGGCCCGGTCATTAGGACCCAGGGCCCGTGCAGCCCAGTGGTGAGGGCAGCACCCGGCATAGGGCAGC ACCGTGTGTCCTGTCCCTGCCCTTCTCTGTGCCTCAGTTTCCTCATTGCTTAGCTGTCTACCTCTTAGGG CTGCTGAAAGCCTTAAATGATTCCACACACTTGGATAGCACCTGATCCCTGCTGGGATTTGAGGGTTTTC ATTACACTTCTGCTAGGATAATCATTTCCATTGTCGAGGTGGGAACACAAAGGCTTGGAGTGGTTAATTC CTTGCCAAGGCCCCGCAGGAGGAAGCAGGGTCCTGCATGGGAGGCCGGCTAGCCTGCCCACTGCCCCATG TCCCCACAGGTGATGGAGGCCTTTGAGCAGGCCGAGCGGAAGCCCAAACCCAACCCCAACCTACTCTTCT CAGACGTGTATCAGGAGATGCCCGCCCAGCTCCGCAAGCAGCAGGAGTCTCTGGCCCGCCACCTGCAGAC CTACGGGGAGCACTACCCACTGGATCACTTCGATAAGTGAGACCTGCTCAGCCCACCCCCACCCATCCTC AGCTACCCCGAGAGGTAGCCCCACTCTAAGGGGAGCAGGGGGACCTGACAGCACACCACTGTCTTCCCCA GTCAGCTCCCTCTAAAATACTCAGCGGCCAGGGCGGCTGCCACTCTTCACCCCTGCTCCTCCCGGCTGTT ACATTGTCAGGGGACAGCATCTGCAGCAGTTGCTGAGGCTCCGTCAGCCCCCTCTTCACCTGTTGTTACA GTGCCTTCTCCCAGGGGCTGGGTGAGGGCACATTCAGGACTAGAAGCCCCTCTGGGCATGGGGTGGACAT GGCAGGTCAGCCTGTGGAACTTGCGCAGGTGCGAGTGGCCAGCAGAGGTCACGAATAAACTGCATCTCTG CGCCTGGCTCTCTACCACCTCTGGTCTTTGTTTCCTGGAGTTTGGGGGTGATTTGAGGCCACCCCCAGCT TCTCCACCTTAGATAAATAAGGTCAAGGCTCTTGAGATACCTACTTCCCCCGGAAGCTTGCGCAAGCTGG AAGGTTAACTTCAGCAGACAGGATGGGGGTGGGGGGGTCCTCCAGAGATGGTCTCCTGCTCTCTCACAGA ATGGGAGAAGCCTGCTGTCCAGCAGAGTGATGGGGAGCCCAGTGGAGCTAGCCCTGCCCAGCAGGGGTGC AGGGGAGCGTCCAGGATGAAGGTCAGGGTGTGGCCAAGCCCTGCTCCCCACCACTCCAGGGCCCCACAGA TGCAAAAACAACCCCAGGCCTCAGAGTGGGGAGTGCATGTTTTTCAAAAACAAAAAGTAGGCAAAAACAG TCCACCACCCCATCTTTCCTGCCCAGGCCCCTGGCTGGGGGAGGCCAAGGAGTGGCTTAAGTTGTCCAGC TTCTGGGCCCTCCTCCCTCCCATCAAGACCTGGAAGGAGGGGCTGAGCCAGGGGCCGGCCCCAGAGGCCC AGGCCAGGTCAGCACCTCCGCCCTCCCCAATGAGAGTCAGCACTGGAGCCTTGGGTCTTGCAGTTGTTTC CAGAGCCGAATGCTGGCCTGGGGGCCCAGGGGCCGTACCAGCAGCAGGTTGCGGAAAGCACAGTGGTCCG CAGTGCGGTCTGCTGGCCAGGCTGTGAGGAAGCCTGGGTGGGCCTGGGGCACCAGGCCCAGGGCTCGGAT GCAAAGGCCAGTGTAGACGTCCTCAAAGGGGAAGGGTGCCACACGGGCTGCCGCCCGCAGCAGCCAGGGT GCCAGGCGCCCGGCAATGACGTAGCCACCCCCGCTTGCATAGGCTGGGTAGCCACCTTCGAAGAAGGACT CGGGCACATAGAAGGGTCCTCCTGGCTTCCGGAGAGGCATGGCCTGGGTAAAGACCTCACCCAGGTAGAG GCTTCGGGCCGAGGCAGGTGGCAGGGCCCGCAGGTGAGCCAGCAGGGCAGGGGTGTGTACAAAGGCATCG TCCTGAGCTCGCAAGACAAAACTCACGGTGGGGCAGTGGCGGCCCAGCCAGGCCAGCAGCAGCAGGTCTT TGAGCGTCTGGTTGAATGGGACGTCGAGGAAGTCCCAGAGCAGCAGGTCACTGTAGCGACGGCTCTCCCA GGCCACTAGTGAGTCTAGGTCAGGCCCCGCCTCACCCACCGGAGACCCTAGCAGGAAGAGCAGCCGGATC CCTGGAGCTGGACTGCCCCACGTCTCTCTCACGGCCTGTCGTTCTGCAAAGCGCCCTGGTTCTGACTTGA CGGCCAACAGCAGGTAGGGGACATCAGTATCTGAGCAGCTGGAGACTTGGCTGCCACCACCTCCAGGCAG CCACTGTGGGAAGCTCCGGCAGGCTGCTGACAGCAAGAAGCGGCGGAGGTCCTTGGGGTAGGAGGCGAAG TCAGGGATCTCGGTGGCGGCGGCGGCCCCCCAAGCCTGGCAGCCCCCCGTTTCAGTGCTGTCCCCACTGG GCAGGGACCCCAGCCGCCACTGCTGCTGGTTCCAGTAAGCAAAGGGCAGCGGGATAGTCTGGCCCAGGCG GGTGGAGAGGTTGGCAGGTAGGGTGGGCTCAGGGTTGGCTGGCGTGGGGCTTGGCGGGGTGCCCCGAGGG CTGGGGTAGGCCTTGCTGAGCCGGGACTCGGATGTCCACTCGATGTACACTTTGAGGCCCAGGAGTGTGA GCAGTGCTGACAGGCAGAGAAGGCACTTGGGGCAGCGCATGACCCGGCCCAGGGAAGGGGCGGCCGCGGG AGCTACAAGGGAGCCACAGGGGAGCCACGGAGGCCATTGGGGTGTGGGGATGGGCCTCCAGAGAGGGCCC AGCCAGGCCCCAGGCAGACAGCTTCACAATCTCCCATAGTCCCCGCCAACCCCCATAACAGATTCTCTCG GTCCCAGATCCTAAACAGCTCCCCTGACCCAGGGACCTCGTTGGTCCTTATTCCTAG
mRNA transcript
>gi|258645170|ref|NM_000709.3| Homo sapiens branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA CTACGTGAGTGCCGGACCGCTGAGTGGTTGTTAGCCAAGATGGCGGTAGCGATCGCTGCAGCGAGGGTCT GGCGGCTAAACCGTGGTTTGAGCCAGGCTGCCCTCCTGCTGCTGCGGCAGCCTGGGGCTCGGGGACTGGC TAGATCTCACCCCCCCAGGCAGCAGCAGCAGTTTTCATCTCTGGATGACAAGCCCCAGTTCCCAGGGGCC TCGGCGGAGTTTATAGATAAGTTGGAATTCATCCAGCCCAACGTCATCTCTGGAATCCCCATCTACCGCG TCATGGACCGGCAAGGCCAGATCATCAACCCCAGCGAGGACCCCCACCTGCCGAAGGAGAAGGTGCTGAA GCTCTACAAGAGCATGACACTGCTTAACACCATGGACCGCATCCTCTATGAGTCTCAGCGGCAGGGCCGG ATCTCCTTCTACATGACCAACTATGGTGAGGAGGGCACGCACGTGGGGAGTGCCGCCGCCCTGGACAACA CGGACCTGGTGTTTGGCCAGTACCGGGAGGCAGGTGTGCTGATGTATCGGGACTACCCCCTGGAACTATT CATGGCCCAGTGCTATGGCAACATCAGTGACTTGGGCAAGGGGCGCCAGATGCCTGTCCACTACGGCTGC AAGGAACGCCACTTCGTCACTATCTCCTCTCCACTGGCCACGCAGATCCCTCAGGCGGTGGGGGCGGCGT ACGCAGCCAAGCGGGCCAATGCCAACAGGGTCGTCATCTGTTACTTCGGCGAGGGGGCAGCCAGTGAGGG GGACGCCCATGCCGGCTTCAACTTCGCTGCCACACTTGAGTGCCCCATCATCTTCTTCTGCCGGAACAAT GGCTACGCCATCTCCACGCCCACCTCTGAGCAGTATCGCGGCGATGGCATTGCAGCACGAGGCCCCGGGT ATGGCATCATGTCAATCCGCGTGGATGGTAATGATGTGTTTGCCGTATACAACGCCACAAAGGAGGCCCG ACGGCGGGCTGTGGCAGAGAACCAGCCCTTCCTCATCGAGGCCATGACCTACAGGATCGGGCACCACAGC ACCAGTGACGACAGTTCAGCGTACCGCTCGGTGGATGAGGTCAATTACTGGGATAAACAGGACCACCCCA TCTCCCGGCTGCGGCACTATCTGCTGAGCCAAGGCTGGTGGGATGAGGAGCAGGAGAAGGCCTGGAGGAA GCAGTCCCGCAGGAAGGTGATGGAGGCCTTTGAGCAGGCCGAGCGGAAGCCCAAACCCAACCCCAACCTA CTCTTCTCAGACGTGTATCAGGAGATGCCCGCCCAGCTCCGCAAGCAGCAGGAGTCTCTGGCCCGCCACC TGCAGACCTACGGGGAGCACTACCCACTGGATCACTTCGATAAGTGAGACCTGCTCAGCCCACCCCCACC CATCCTCAGCTACCCCGAGAGGTAGCCCCACTCTAAGGGGAGCAGGGGGACCTGACAGCACACCACTGTC TTCCCCAGTCAGCTCCCTCTAAAATACTCAGCGGCCAGGGCGGCTGCCACTCTTCACCCCTGCTCCTCCC GGCTGTTACATTGTCAGGGGACAGCATCTGCAGCAGTTGCTGAGGCTCCGTCAGCCCCCTCTTCACCTGT TGTTACAGTGCCTTCTCCCAGGGGCTGGGTGAGGGCACATTCAGGACTAGAAGCCCCTCTGGGCATGGGG TGGACATGGCAGGTCAGCCTGTGGAACTTGCGCAGGTGCGAGTGGCCAGCAGAGGTCACGAATAAACTGC ATCTCTGCGCCTGGCTCTCTACCAAAAAAAAAAAAAAAAAA
Protein
>gi|11386135|ref|NP_000700.1| 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform 1 precursor [Homo sapiens] MAVAIAAARVWRLNRGLSQAALLLLRQPGARGLARSHPPRQQQQFSSLDDKPQFPGASAEFIDKLEFIQP NVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGT HVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLA TQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYR GDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDE VNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQL RKQQESLARHLQTYGEHYPLDHFDK
Neutral mutations
Disease causing mutations
References
branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA) branched chain keto acid dehydrogenase E1, beta polypeptide (BCKDHB) dihydrolipoamide branched chain transacylase E2 (DBT) dihydrolipoamide dehydrogenase (DLD)