Difference between revisions of "Homology-based structure prediction (PKU)"
From Bioinformatikpedia
(→Modelbconstruction) |
|||
| Line 1: | Line 1: | ||
| + | ==Short Task Description== |
||
| − | Now that we found information about the [[Sequence-based predictions (PKU)|function and secondary structure]] of our protein we will determine the 3D structure as well as how much influence one, or several, SNPs has/have on this structure. Out of the variety of methods to be used for this topic, we chose homology modeling as a first approach to our goal. |
||
| + | After the sequence based predictions of [[Sequence-based predictions (PKU)|function and secondary structure]] for our protein we will determine the 3D structure of the wild type protein and pbserve the influence one or several SNPs have on this structure. Of the variety of methods to be used for tertiary structure prediction, we choose homology modeling as a first approach to our goal. Read the complete task description [[Task_homologyModelling|here]. |
||
| + | ==Model Construction== |
||
| − | ==Modelconstruction== |
||
| − | Here we will show the steps we took building the models we then use and evaluate. In order to |
+ | Here we will show the steps we took building the models we then use and evaluate. In order to start the sheer model-building we first have to construct some datasets, which will be the founding of our models. |
| − | === |
+ | ===Datasets=== |
==Modelevaluation== |
==Modelevaluation== |
||
Revision as of 18:12, 22 May 2012
Short Task Description
After the sequence based predictions of function and secondary structure for our protein we will determine the 3D structure of the wild type protein and pbserve the influence one or several SNPs have on this structure. Of the variety of methods to be used for tertiary structure prediction, we choose homology modeling as a first approach to our goal. Read the complete task description [[Task_homologyModelling|here].
Model Construction
Here we will show the steps we took building the models we then use and evaluate. In order to start the sheer model-building we first have to construct some datasets, which will be the founding of our models.
