Difference between revisions of "HSSP curve"

From Protein Prediction 2 Winter Semester 2014
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[[File:Hssp curve.png | 300px | left | Different thresholds for HSSP-curve]]
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[[File:Hssp curve.png | 200px | left | Different thresholds for HSSP-curve]]
[[File:Threshholds.png | 300px | center | Different thresholds for HSSP-curve]]
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[[File:Threshholds.png | 200px | center | Different thresholds for HSSP-curve]]
   
   
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== Core Functionalities ==
 
== Core Functionalities ==
   
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= Progress =
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<div style=" text-align:left; width: 60% ; overflor:auto; height:10em border:2px">
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{| class="wikitable"
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|-
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! scope="col" width="70%" | Task !! scope="col" width="30%" | Implemented
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|-
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| Core Functionality || No
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|-
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| Drag nodes || No
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|-
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| Display additional info on mouse-over || No
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|-
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| Edit graph and export changes || No
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|-
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| PBseq format compatibility || No
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|-
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| Connect (.ct) format compatibility || No
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|}
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</div>
   
   

Revision as of 12:31, 20 November 2014

Introduction to HSSP curve?

HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment of all available homologues and a sequence profile characteristic of the family. The list of homologues is the result of a database search in SwissProt using a position-weighted dynamic programming method for sequence profile alignment (MaxHom). The database is updated frequently. The listed homologues are very likely to have the same 3-D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of aligned sequence families, but also a database of implied secondary and tertiary structures covering 29% of all SwissProt-stored sequences.


Different thresholds for HSSP-curve
Different thresholds for HSSP-curve


Existing visualisations

Core Functionalities

Progress

Task Implemented
Core Functionality No
Drag nodes No
Display additional info on mouse-over No
Edit graph and export changes No
PBseq format compatibility No
Connect (.ct) format compatibility No


References

http://en.wikipedia.org/wiki/Homology-derived_Secondary_Structure_of_Proteins

http://www.ncbi.nlm.nih.gov/pubmed/?term=UniqueProt%3A+creating+representative+protein+sequence+sets

http://en.wikipedia.org/wiki/Protein_superfamily

http://nar.oxfordjournals.org/content/24/1/201.full.pdf